Masafumi Shimojo

シモジョウマサフミ | Masafumi Shimojo

Affiliation and department：

Research field (5)： Nervous system function , Neuropathology , Neuroscience - general , Cell biology , Molecular biology

Research theme for competitive and other funds (8)：

2024 - 2028 生体脳イメージングを基軸とした回路炎症病態の可視化と制御
2022 - 2026 認知症病態における多感覚情報の統合メカニズム破綻
2021 - 2024 神経回路イメージングによる脳機能理解と病態メカニズム制御
2021 - 2023 炎症病態により誘導される回路再編メカニズムと遺伝学的制御
2018 - 2021 Development of imaging-based early diagnosis biomarkers of neurodegenerative disorders

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Papers (23)：

Rin Yanai, Tomoki T Mitani, Etsuo A Susaki, Takeharu Minamihisamatsu, Masafumi Shimojo, Yuri Saito, Hiroshi Mizuma, Nobuhiro Nitta, Daita Kaneda, Yoshio Hashizume, et al. A novel tauopathy model mimicking molecular and spatial aspects of human tau pathology. Brain Communications. 2024. 6. 5
Yumi Matsushita, Kaede Yoshida, Miyuki Yoshiya, Takahiro Shimizu, Satoshi Tsukamoto, Yuichi Takeuchi, Makoto Higuchi, Masafumi Shimojo. TRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in mammalian brain. 2024
Takehiro Kudo, Hiroyuki Takuwa, Manami Takahashi, Takuya Urushihata, Masafumi Shimojo, Kazuaki Sampei, Mitsugu Yamanaka, Yutaka Tomita, Naruhiko Sahara, Tetsuya Suhara, et al. Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model. iScience. 2023. 26. 4. 106342-106342
Taeko Kimura, Maiko Ono, Chie Seki, Kazuaki Sampei, Masafumi Shimojo, Kazunori Kawamura, Ming-Rong Zhang, Naruhiko Sahara, Yuhei Takado, Makoto Higuchi. A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model. European Journal of Nuclear Medicine and Molecular Imaging. 2022. 49. 13. 4298-4311
Maiko Ono, Masaaki Komatsu, Bin Ji, Yuhei Takado, Masafumi Shimojo, Takeharu Minamihisamatsu, Eiji Warabi, Toru Yanagawa, Gen Matsumoto, Ichio Aoki, et al. Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy. Aging cell. 2022. e13615

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MISC (26)：

下條雅文. 超音波脳神経治療の基礎・前臨床分野の最前線マウス大脳神経細胞の超音波応答メカニズム. 日本脳神経超音波学会総会・日本栓子検出と治療学会プログラム・抄録集. 2024. 43回・27回. 106-106
横井洸希, 松下有美, 下條雅文, 樋口真人, 今城哉裕, 森田剛. 細胞への最適照射条件検討に資する周波数可変in vitro超音波照射システムの提案. 精密工学会大会学術講演会講演論文集(CD-ROM). 2024. 2024
山崎友照, 藤永雅之, 大久保崇之, 下條雅文, 小野麻衣子, 永井裕司, 小川政直, 念垣信樹, 南本敬史, 樋口真人, et al. 新規レポーター遺伝子イメージング剤[18F]FE-TMP-d4の小動物を用いた有効性評価. 核医学. 2023. 60. Suppl. S221-S221
矢内凛, 南久松丈晴, 下條雅文, 洲崎悦生, 三谷智樹, 上田泰己, 張明栄, 佐原成彦, 樋口真人. 透明化とPETを用いた新規タウオパチーモデルマウスの全脳3Dイメージング. Dementia Japan. 2023. 37. 4. 682-682
矢内凜, 南久松丈晴, 下條雅文, 樋口真人, 佐原成彦. 新規Rosa26-Knockinタウオパチーマウスを用いたミクログリア動態の探索. 老年精神医学雑誌. 2022. 33. 増刊II. 255-255

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Lectures and oral presentations (23)：

マウス大脳神経細胞の超音波応答メカニズム
(日本脳神経超音波学会 2024)
Recent Advances in ultrasound technologies for biomedical research
(日本生理学会 2024)
マウス大脳神経細胞の超音波応答メカニズム
(2024)
Ultrasound neuromodulation induces network excitation of cortical neurons through the activation of mechanosensitive channels” Invited Symposium
(The Korea Society for Therapeutic Ultrasound 2023)
PET imaging of animal models for neurological disorders
(2023)

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Work history (7)：

2022/07 - 現在 National Institutes for Quantum and Radiological Science and Technology
2022/04 - National Institutes for Quantum and Radiological Science and Technology Department of Functional Brain Imaging Principal Researcher
2021/04 - National Institutes for Quantum and Radiological Science and Technology Department of Functional Brain Imaging Senior Researcher
2016/04 - National Institutes for Quantum and Radiological Science and Technology Dept. of Functional Brain Imaging Research Researcher
2014/10 - National institute of Radiological Sciences Researcher

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Association Membership(s) (5)：

北米神経科学会 , 日本生理学会 , 日本分子生物学会 , 日本神経化学会 , THE JAPAN NEUROSCIENCE SOCIETY

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