Rchr
J-GLOBAL ID:201901013217050901   Update date: Jun. 13, 2024

Masafumi Shimojo

シモジョウ マサフミ | Masafumi Shimojo
Affiliation and department:
Research field  (5): Nervous system function ,  Neuropathology ,  Neuroscience - general ,  Cell biology ,  Molecular biology
Research theme for competitive and other funds  (8):
  • 2024 - 2028 生体脳イメージングを基軸とした回路炎症病態の可視化と制御
  • 2022 - 2026 認知症病態における多感覚情報の統合メカニズム破綻
  • 2021 - 2024 神経回路イメージングによる脳機能理解と病態メカニズム制御
  • 2021 - 2023 炎症病態により誘導される回路再編メカニズムと遺伝学的制御
  • 2018 - 2021 Development of imaging-based early diagnosis biomarkers of neurodegenerative disorders
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Papers (23):
  • Yumi Matsushita, Kaede Yoshida, Miyuki Yoshiya, Takahiro Shimizu, Satoshi Tsukamoto, Yuichi Takeuchi, Makoto Higuchi, Masafumi Shimojo. TRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in mammalian brain. 2024
  • Takehiro Kudo, Hiroyuki Takuwa, Manami Takahashi, Takuya Urushihata, Masafumi Shimojo, Kazuaki Sampei, Mitsugu Yamanaka, Yutaka Tomita, Naruhiko Sahara, Tetsuya Suhara, et al. Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model. iScience. 2023. 26. 4. 106342-106342
  • Taeko Kimura, Maiko Ono, Chie Seki, Kazuaki Sampei, Masafumi Shimojo, Kazunori Kawamura, Ming-Rong Zhang, Naruhiko Sahara, Yuhei Takado, Makoto Higuchi. A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model. European Journal of Nuclear Medicine and Molecular Imaging. 2022. 49. 13. 4298-4311
  • Maiko Ono, Masaaki Komatsu, Bin Ji, Yuhei Takado, Masafumi Shimojo, Takeharu Minamihisamatsu, Eiji Warabi, Toru Yanagawa, Gen Matsumoto, Ichio Aoki, et al. Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy. Aging cell. 2022. e13615
  • Masafumi Shimojo, Maiko Ono, Hiroyuki Takuwa, Koki Mimura, Yuji Nagai, Masayuki Fujinaga, Tatsuya Kikuchi, Maki Okada, Chie Seki, Masaki Tokunaga, et al. A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains. The EMBO journal. 2021. 40. 22. e107757
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MISC (5):
  • 山崎友照, 藤永雅之, 大久保崇之, 大久保崇之, 下條雅文, 小野麻衣子, 永井裕司, 小川政直, 念垣信樹, 小川政直, et al. 新規レポーター遺伝子イメージング剤[18F]FE-TMP-d4の小動物を用いた有効性評価. 核医学(Web). 2023. 60. Supplement
  • 矢内凛, 南久松丈晴, 下條雅文, 洲崎悦生, 三谷智樹, 上田泰己, 張明栄, 佐原成彦, 樋口真人. 透明化とPETを用いた新規タウオパチーモデルマウスの全脳3Dイメージング. Dementia Japan. 2023. 37. 4
  • 下條雅文, 南久松丈晴, 高橋真奈美, 田桑弘之, 松下有美, 矢内凛, 湊原圭一郎, 小野麻衣子, 高堂裕平, 張明栄, et al. rTg4510認知症モデル動物脳における炎症性アストロサイト病態の画像解析. 日本神経化学会大会抄録集(Web). 2022. 65th
  • 大久保崇之, 大久保崇之, 下條雅文, 小野麻衣子, 藤永雅之, 小川政直, 小川政直, 念垣信樹, 念垣信樹, 永井裕司, et al. ecDHFRイメージング用の遺伝子レポータートPETトレーサー[18F]FHP-TMPの開発. 核医学(Web). 2022. 59. Supplement
  • 小野麻衣子, 高橋真奈美, 下沢明希, 藤永雅之, 森若菜, 永井裕司, 三村喬生, 熊田勝志, 下條雅文, 高堂裕平, et al. α-synuclein病変の蓄積・伝播を生体脳で可視化する分子プローブの開発. Dementia Japan. 2021. 35. 4
Work history (7):
  • 2022/07 - 現在 National Institutes for Quantum and Radiological Science and Technology
  • 2022/04 - National Institutes for Quantum and Radiological Science and Technology Department of Functional Brain Imaging Principal Researcher
  • 2021/04 - National Institutes for Quantum and Radiological Science and Technology Department of Functional Brain Imaging Senior Researcher
  • 2016/04 - National Institutes for Quantum and Radiological Science and Technology Dept. of Functional Brain Imaging Research Researcher
  • 2014/10 - National institute of Radiological Sciences Researcher
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Association Membership(s) (5):
北米神経科学会 ,  日本生理学会 ,  日本分子生物学会 ,  日本神経化学会 ,  THE JAPAN NEUROSCIENCE SOCIETY
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