Oda Akihisa

オダアキヒサ | Oda Akihisa

Research field (1)： Immunology

Research keywords (4)： Immune response , Extramedullary hematopoiesis , Spleen microenvironment , Hemophilia

Research theme for competitive and other funds (7)：

2021 - 2024 血友病Aインヒビター産生応答を制御する脾臓免疫ニッチの同定
2020 - 2024 血管内皮細胞からARDSの病態を解明する-ヒストン修飾酵素SETDB2の意義-
2020 - 2024 Development of Universal Cell Therapy for Hemophilia A
2018 - 2021 Disruption of splenic extramedullary hematopoiesis leads to myeloproliferative disorders
2015 - 2017 The role of the mesenchymal cells expressing Tlx1 in the adult spleen

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Papers (14)：

Shota Sonobe, Masahiro Kitabatake, Atsushi Hara, Makiko Konda, Noriko Ouji-Sageshima, Chiyoko Terada-Ikeda, Ryutaro Furukawa, Natsuko Imakita, Akihisa Oda, Maiko Takeda, et al. THE CRITICAL ROLE OF THE HISTONE MODIFICATION ENZYME SETDB2 IN THE PATHOGENESIS OF ACUTE RESPIRATORY DISTRESS SYNDROME. Shock (Augusta, Ga.). 2023. 60. 1. 137-145
Shoichiro Saito, Masahiro Kitabatake, Noriko Ouji-Sageshima, Tatsuro Ogawa, Akihisa Oda, Tomoko Nishimura, Tatsuki Nishioka, Satoki Fushimi, Atsushi Hara, Shigeyuki Shichino, et al. Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development. American journal of respiratory cell and molecular biology. 2023. 69. 3. 328-339
小田朗永, 古川晶子, 北畠正大, 王寺典子, 堀内薫, 笹井香那, 下西成人, 中島由翔, 荻原建一, 武山雅博, et al. In vitro培養系による抗FVIII応答の誘導. 日本血栓止血学会誌. 2023. 34. 2. 239-239
Akihisa Oda, Shoko Furukawa, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Kaoru Horiuchi, Yuto Nakajima, Kenichi Ogiwara, Ryo Goitsuka, Midori Shima, et al. The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor. Thrombosis research. 2023
Yuto Nakajima, Masahiro Takeyama, Akihisa Oda, Naruto Shimonishi, Keiji Nogami. Factor VIII mutated with Lys1813Ala within the factor IXa-binding region enhances intrinsic coagulation potential. Blood Advances. 2022

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MISC (1)：

小田朗永, 中島由翔, 下西成人, 北畠正大, 伊藤利洋, 野上恵嗣. 血友病Aインヒビター産生細胞の脾臓における動態. 日本血栓止血学会誌. 2021. 32. 2. 226-226

Books (3)：

脾臓髄外造血と生体造血ニッチの変遷
科学評論社血液内科第78巻第6号 2019
成体脾臓における髄外造血ニッチとその構成要素
医歯薬出版株式会社医学のあゆみ第26巻 2018
好塩基球におけるIL-4産生誘導シグナル伝達機構とTh2分化
科学評論社臨床免疫・アレルギー科 54:546-553 2010

Lectures and oral presentations (1)：

The cell components of perifollicular hematopoietic niche in the spleen.
(The 7th International Workshop of Kyoto T Cell Conference 2017)

Education (1)：

2004 - 2007 東京理科大学大学院後期博士課程生命科学研究科分子生物学研究部門

Professional career (1)：

博士(理学) (東京理科大学)

Work history (4)：

2018/04 - 2019/03 Tokyo University of Science Research Institute for Biological Sciences, Division of Development and Ageing
2013/04 - 2018/04 Tokyo University of Science Research Institute for Biological Sciences, Division of Development and Ageing
2011/04 - 2013/03 Shinshu University School of Medicine
2009/04 - 2011/03 信州大学医学研究科移植免疫感染症講座奨励研究員

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