Rchr
J-GLOBAL ID：201901013256543966
Update date: Jul. 17, 2024
Hayashi Gosuke
ハヤシ ゴウスケ | Hayashi Gosuke
Affiliation and department：
Job title：
Associate professor
Research field (2)：
Biochemistry
, Molecular biochemistry
Research keywords (3)：
Epigenetics
, Peptide chemistry
, Chemical protein synthesis
Research theme for competitive and other funds (9)：
- 2023 - 2028 Development of single-molecule peptide sequencing method
- 2021 - 2023 Ubiquitin Chemo-technology by Chemical Protein Synthesis and Molecular Evolution
- 2019 - 2023 有機化学を基盤としたエピゲノム修飾ヌク レオソーム再構成技術の確立
- 2020 - 2022 生体分子夾雑系で機能するD体人工抗体の開発
- 2020 - 2021 Sタンパク質結合人工抗体を用いたコロナウィルス濃縮および抗原検査法の開発
- 2019 - 2021 Efficient Chemical Synthesis of Polyubiquitin and Ubiquitinated Proteins
- 2018 - 2021 DNAを足場としたペプチド断片の同時連結反応によるタンパク質の効率的化学合成
- 2015 - 2018 分解反応の遷移状態構造に立脚した新型核酸医薬を志向した核酸酵素の創製
- 2013 - 2015 ヒストンコード研究の基盤となる多様な修飾を有するヌクレオソーム構築法の開発と応用
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Papers (44)：
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Koki Nakatsu, Akimitsu Okamoto, Gosuke Hayashi, Hiroshi Murakami. Repetitive Thiazolidine Deprotection Using a Thioester-Compatible Aldehyde Scavenger for One-Pot Multiple Peptide Ligation. Angewandte Chemie (International ed. in English). 2022. 61. 39. e202206240
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Naoki Kamo, Gosuke Hayashi, Akimitsu Okamoto. Silyl-protected propargyl glycine for multiple labeling of peptides by chemoselective silyl-deprotection. Tetrahedron Letters. 2021. 73
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Motoyuki Ogata, Gosuke Hayashi, Anri Ichiu, Akimitsu Okamoto. L-DNA-tagged fluorescence: In situ hybridization for highly sensitive imaging of RNAs in single cells. Organic and Biomolecular Chemistry. 2020. 18. 40. 8084-8088
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Nakatsu Koki, Yanase Masafumi, Hayashi Gosuke, Okamoto Akimitsu. Fmoc-Compatible and C-terminal-Sequence-Independent Peptide Alkyl Thioester Formation Using Cysteinylprolyl Imide. ORGANIC LETTERS. 2020. 22. 12. 4670-4674
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Nakatsu K, Hayashi G, Okamoto A. Toolbox for chemically synthesized histone proteins. Current opinion in chemical biology. 2020. 58. 10-19
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Education (3)：
- 2006 - 2009 Osaka University Graduate School, Division of Natural Science Department of Chemistry
- 2004 - 2006 Kyoto University Graduate School, Division of Engineering Department of Synthetic Chemistry and Biological Chemistry
- 2000 - 2004 Kyoto University Faculty of Engineering Undergraduate School of Industrial Chemistry
Professional career (1)：
Work history (7)：
- 2019/03/01 - 現在 Nagoya University Graduate School of Engineering, Department of Bimolecular Engineering Associate Professor
- 2019/03/01 - 現在 Nagoya University Graduate School of Engineering Biomolecular Engineering 1 Associate professor
- 2013/02/01 - 2019/02/28 The University of Tokyo Graduate School of Engineering, Department of Chemistry and Biotechnology Assistant Professor
- 2012/06/01 - 2013/01/31 The University of Tokyo Research Center for Advanced Science and Technology Assistant Professor
- 2011/02/16 - 2012/05/31 Boston University Department of Biomedical Engineering Postdoctral Fellow (JSPS Reserch Fellowship for Young Scientists PD and Overseas Research Fellowships)
- 2009/04/01 - 2011/02/15 The University of Tokyo Research Center for Advanced Science and Technology Postdoctral Fellow (JSPS Research Fellowship for Young Scientists PD)
- 2006/04/01 - 2009/03/31 Osaka University Graduate School of Science, Department of Chemistry JSPS Research Fellowship of Young Scientists DC1
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Awards (7)：
- 2020/03 - 日本化学会 若い世代の特別講演賞
- 2019/11 - 日本ペプチド学会 日本ペプチド学会 奨励賞
- 2018/03 - 日本エピジェネティクス研究会 日本エピジェネティクス研究会 奨励賞
- 2017/09 - 日本化学会 生体機能関連化学部会、バイオテクノロジー部会 バイオ関連化学シンポジウム 講演賞
- 2017/03 - 日本化学会 日本化学会優秀講演賞(学術)
- 2010/12 - PACIFICHEM2010 Outstanding Young Researcher Poster Presentation Award
- 2005/09 - 日本核酸化学会 Poster Award in 4th International Symposium on Nucleic Acids Chemistry
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Association Membership(s) (5)：
日本エピジェネティクス研究会
, 日本ケミカルバイオロジー学会
, 日本分子生物学会
, 日本生化学会
, 日本化学会
