Nagao Asuteka

ナガオアステカ | Nagao Asuteka

Research field (1)： Molecular biology

Research theme for competitive and other funds (6)：

2021 - 2023 Development of a method to determine RNA-protein complex by cryo-EM
2020 - 2023 investigation of a novel translational regulatory mechanism based on tRNA usage
2018 - 2020 exploring the significance of initiation methionine by creation of non-methionine translation initiation E. coli
2014 - 2019 Analysis of novel functions of nascent-chain in quality controls of mRNA and protein
2013 - 2015 Quality control of protein synthesis by peptidyl-tRNA drop off in the early elongation stage

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Papers (17)：

Naho Akiyama, Kensuke Ishiguro, Takeshi Yokoyama, Kenjyo Miyauchi, Asuteka Nagao, Mikako Shirouzu, Tsutomu Suzuki. Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nature Structural & Molecular Biology. 2024
Saori Ueda, Mikako Yagi, Ena Tomoda, Shinya Matsumoto, Yasushi Ueyanagi, Yura Do, Daiki Setoyama, Yuichi Matsushima, Asuteka Nagao, Tsutomu Suzuki, et al. Mitochondrial haplotype mutation alleviates respiratory defect of MELAS by restoring taurine modification in tRNA with 3243A > G mutation. Nucleic acids research. 2023. 51. 14. 7480-7495
Taisei Wakigawa, Mari Mito, Haruna Yamashiro, Kotaro Tomuro, Haruna Tani, Kazuhito Tomizawa, Takeshi Chujo, Asuteka Nagao, Takeo Suzuki, Fan-Yan Wei, et al. Complexity and dynamics ofin organellotranslation landscape assessed by high-resolution mitochondrial ribosome profiling. 2023
Asuteka Nagao, Yui Nakanishi, Yutaro Yamaguchi, Yoshifumi Mishina, Minami Karoji, Takafumi Toya, Tomoya Fujita, Shintaro Iwasaki, Kenjyo Miyauchi, Yuriko Sakaguchi, et al. Quality control of protein synthesis in the early elongation stage. Nature communications. 2023. 14. 1. 2704-2704
Ena Tomoda, Asuteka Nagao, Yuki Shirai, Kana Asano, Takeo Suzuki, Brendan J Battersby, Tsutomu Suzuki. Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases. Nucleic Acids Research. 2023

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MISC (3)：

長尾翌手可, 中西由衣, 山口悠太郎, 藤田智也, 藤田智也, 岩崎信太郎, 宮内健常, 坂口裕理子, 鈴木勉. 翻訳伸長脱落ペプチジルtRNAの網羅的解析と新規翻訳精度維持機構の探索. 日本生化学会大会(Web). 2019. 92nd
長尾翌手可, 小原光弘, 宮内健常, 横堀伸一, 山岸明彦, 渡辺公綱, 鈴木勉. 棘皮動物ミトコンドリアにおける変則遺伝暗号の確立に寄与する新規修飾塩基の発見とその機能解析. 日本RNA学会年会要旨集. 2017. 19th
井田智章, 居原秀, 魏范研, 富澤一仁, 長尾翌手可, 鈴木勉, 熊谷嘉人, 澤智裕, 笠松真吾, 本橋ほづみ, et al. タンパク質ポリサルファ化の分子メカニズムの解明. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [3T21p-03(3P0211)]

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