Rchr
J-GLOBAL ID：201901013533033970   Update date: Feb. 01, 2024

Hongu Tsunaki

ホングウ ツナキ | Hongu Tsunaki
Affiliation and department：
Cancer Research Institute, Kanazawa University

About Cancer Research Institute, Kanazawa University


Job title： Assistant professor
Research field  (1)： Tumor biology
Research keywords  (6)： Cancer stem cells ,  Vasculature ,  Metastatic niches ,  Tumor Microenvironment ,  Metastasis ,  Cancer
Research theme for competitive and other funds  (10)：
  • 2023 - 2026 乳癌幹細胞のプレシジョン医療を実現する1細胞ゲノム/蛋白質統合解析
  • 2022 - 2024 Functional analysis of perivascular metastatic niche factors in lung
  • 2023 - 乳癌幹細胞性を規定する遺伝子変異の同定
  • 2023 - 1細胞ゲノム/蛋白質統合解析による「乳がん幹細胞プレシジョン医療」の創出
  • 2023 - 乳癌幹細胞のプレシジョン医療を実現する1細胞ゲノム/ 蛋白質統合解析
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Papers (35)：
  • Yuming Wang, Tsunaki Hongu, Tatsunori Nishimura, Yasuto Takeuchi, Hiroshi Takano, Takiko Daikoku, Ryoji Yao, Noriko Gotoh. Mitochondrial one-carbon metabolic enzyme MTHFD2 facilitates mammary gland development during pregnancy. Biochemical and biophysical research communications. 2023. 674. 183-189
  • Tsunaki Hongu, Maren Pein, Jacob Insua-Rodríguez, Ewgenija Gutjahr, Greta Mattavelli, Jasmin Meier, Kristin Decker, Arnaud Descot, Matthias Bozza, Richard Harbottle, et al. Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs. Nature cancer. 2022. 3. 4. 486-504
  • SangJoon Lee, Akari Ishitsuka, Takahiro Kuroki, Yu-Hsien Lin, Akira Shibuya, Tsunaki Hongu, Yuji Funakoshi, Yasunori Kanaho, Kyosuke Nagata, Atsushi Kawaguchi. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes. JCI insight. 2021. 6. 16
  • Jouda Gamara, Lynn Davis, Andrew Z Leong, Nathalie Pagé, Emmanuelle Rollet-Labelle, Chenqi Zhao, Tsunaki Hongu, Yuji Funakoshi, Yasunori Kanaho, Fawzi Aoudji, et al. Arf6 regulates energy metabolism in neutrophils. Free radical biology & medicine. 2021. 172. 550-561
  • Tsunaki Hongu, Thordur Oskarsson. Addicted to Acidic Microenvironment. Developmental Cell. 2020. 55. 4. 381-382
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MISC (23)：
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Patents (3)：
Books (5)：
  • 低分子量Gタンパク質Arf6の個体における多彩な生理機能(生化学)
    2016
  • 新たな抗がん剤創薬標的としての低分子量G蛋白質Arf6(ファルマシア)
    2015
  • モデル動物の作製と利用-脂質代謝異常と関連疾患
    2015
  • ホスホリパーゼDの多彩な生理機能と癌における役割(医学のあゆみ)
    2014
  • Phospholipases in Health and Disease
    Springer 2014
Education (1)：
  • 2006 - 2011 University of Tsukuba
Professional career (1)：
  • 博士(医学) (筑波大学)
Work history (6)：
  • 2022/03 - 現在 Cancer Research Institute, Kanazawa University
  • 2018/04 - 2022/02 German Cancer Research Center ポストドクトラルフェロー
  • 2015/10 - 2018/03 German Cancer Research Center 客員研究員
  • 2014/09 - 2018/03 University of Tsukuba
  • 2012/04 - 2014/08 University of Tsukuba
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Awards (4)：
  • 2023 - 日本がん転移学会 優秀ポスター賞
  • 2019 - JSPS Leading Initiative for Excellent Young Researchers
  • 2018/04 - 上原記念生命科学財団 リサーチフェローシップ
  • 2008 - 文部科学省特定領域班会議 優秀ポスター賞
Association Membership(s) (5)：
日本薬学会 ,  THE JAPANESE CANCER ASSOCIATION ,  日本がん転移学会 ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  JAPAN SOCIETY FOR CELL BIOLOGY
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