Ii Hiromi

Affiliation and department：
Homepage URL (1)： http://labo.kyoto-phu.ac.jp/oncology/

Research field (1)： Tumor biology

Research keywords (2)： cancer cell metabolism , cancer research

Research theme for competitive and other funds (5)：

Papers (42)：

Yumiko Saito, Keiko Taniguchi, Hiromi Ii, Mano Horinaka, Susumu Kageyama, Susumu Nakata, Osamu Ukimura, Toshiyuki Sakai. Identification of c-Met as a novel target of γ-glutamylcyclotransferase. Scientific reports. 2023. 13. 1. 11922-11922
Yukie Nohara, Keiko Taniguchi, Hiromi Ii, Shun Masuda, Hiroko Kawakami, Masakatsu Matsumoto, Yasunao Hattori, Susumu Kageyama, Toshiyuki Sakai, Susumu Nakata, et al. Development of an activity-based chemiluminogenic probe for γ-glutamylcyclotransferase. Organic & biomolecular chemistry. 2023
Kaito Ohta, Hiromi Ii, Chiami Moyama, Shota Ando, Hisanori Nambu, Susumu Nakata, Naoto Kojima. Thiophene Carboxamide Analogs with Long Alkyl Chains Comprising Ethylene Glycol Units Inhibit Glioblastoma Cell Proliferation by Activating AMPK. Journal of Medicinal Chemistry. 2023
齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行. c-Met発現低下を介したγ-glutamylcyclotrasnferase(GGCT)阻害による前立腺がん細胞増殖抑制の新規分子機構の解明(Identification of c-Met as a novel target of gamma-glutamylcyclotrasnferase in a prostate cancer cell line). 日本泌尿器科学会総会. 2023. 110回. AOP09-07
Chiami Moyama, Mitsugu Fujita, Hitoshi Okamoto, Hiromi Ii, Susumu Nakata. Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells. Cancer genomics & proteomics. 2023. 20. 2. 195-202

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MISC (86)：

大田海斗, 飯居宏美, 茂山千愛美, 安藤翔太, 岩崎宏樹, 南部寿則, 中田晋, 小島直人. N-トリエチレングリコール含有アルキル-3-カルボキサミドの合成と膠芽腫に対する抗腫瘍効果. 日本薬学会九州山口支部大会講演要旨集(CD-ROM). 2023. 40th
飯居宏美, 近藤真帆, 伊藤公成, 中田晋. Suppression of Wnt pathway is involved in anticancer activity of GGCT knockdown in colorectal cancer cells. 日本癌学会学術総会抄録集(Web). 2023. 82nd
山本夏菜, 山向千晶, 松下眞子, 橋本彩花, 野瀬梢, 茂山千愛美, 藤田貢, 飯居宏美, 中田晋. The regulation of GGCT and hedgehog ligands expression in a glioblastoma stem cell model induced by sh-TP53, EGFRvIII and NRasG12V. 日本薬学会年会要旨集(Web). 2023. 143rd
野瀬梢, 森昌也, 茂山千愛美, 飯居宏美, 藤田貢, 中田晋. γ-glutamylcyclotransferase knockdown inhibits proliferation of glioblastoma stem cells. 日本癌学会学術総会抄録集(Web). 2023. 82nd
大田海斗, 藤井真人, 茂山千愛美, 飯居宏美, 中田晋, 岩崎宏樹, 山下正行, 南部寿則, 小島直人. Synthesis and Antitumor Activity of Novel Analog of Acetogenin Thiophene Analog with Triethylene Glycol in place of THF Moiety. 日本薬学会年会要旨集(Web). 2023. 143rd

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Patents (2)：

Lectures and oral presentations (5)：

γグルタミルシクロトランスフェラーゼ阻害剤pro-GAはMCF7担癌マウスにおいて抗腫瘍効果を示す
(日本薬学会年会要旨集 2022)
γ-グルタミルシクロトランスフェラーゼを標的とした新規抗がん剤開発
(第77回日本癌学会学術総会 2018)
A novel prodrug of γ-glutamylcyclotransferase inhibitor has anti-proliferative activity in vitro and anti-cancer activity in vivo
(20th international conference on medicinal chemistry & rational drugs 2018)
Development of a new anti-cancer drug that targets the novel cancer-related protein C7orf24
(The 3rd International Symposium of Training Plan for Oncology Professionals 2015)
C7orf24阻害による新規細胞死機構の検討
(第64回日本薬学会近畿支部総会・大会 2014)

Education (3)：

Professional career (1)：

Work history (2)：

2010/07 - 現在 Kyoto Pharmaceutical University Department of Clinical Oncology Assistant professor
2008/10 - 2010/03 University of Washington Department of Chemistry and Biochemistry Postdoctoral fellow

Awards (2)：

2015/02 - The 3rd International Symposium of Training Plan for Oncology Professionals Best Presentation Award Development of a new anti-cancer drug that targets the novel cancer-related protein C7orf24.
2007/10 - XVI International Symposium on Drug Affecting Lipid Metabolism Young Investigator Award Cytosolic phospholipase A2α promotes atherosclerotic lesions in mice

Association Membership(s) (2)：

THE JAPANESE CANCER ASSOCIATION , THE PHARMACEUTICAL SOCIETY OF JAPAN

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