Rchr
J-GLOBAL ID：201901013970177396   Update date: Mar. 18, 2024

Kawabata Shigeru

カワバタ シゲル | Kawabata Shigeru
Affiliation and department：
Osaka Medical and Pharmaceutical University Department of Pathology, Division of Comprehensive Medicine

About Osaka Medical and Pharmaceutical University Department of Pathology, Division of Comprehensive Medicine


Job title： Associate professor
Research field  (1)： Tumor biology
Research keywords  (7)： Pulmonary Disease and Neoplasms, ,  Surgical Pathology, ,  Cancer Biology (Tumorigenesis and Signal Transduction), ,  Translational Cancer Research, ,  Mouse models of Cancer, ,  Cancer Therapeutic Development and Anti-Cancer Drug Resistance, ,  Cancer Prevention Research
Research theme for competitive and other funds  (4)：
  • 2023 - 2026 小細胞肺がんでのmTOR・NOTCH1・YAP1の相互関係解析と抗がん剤耐性克服の検証
  • 2020 - 2024 小細胞肺癌でのがん免疫療法におけるmTOR阻害剤併用の有用性の検証(2020年4月-2024年3月)
  • 2019 - 2020 小細胞肺癌に対するmTOR阻害剤を用いた維持療法の臨床開発: 免疫チェックポイント機構に関連するバイオマーカー解析
  • 2010 - 2012 The Role of EGFR in Endolymphatic Sac Tumors (April 2010-March 2012)
Papers (67)：
  • Onishi Y, Kawabata S, Yasuda E, Ibuki N, Azuma H, Hirota Y, Ueda K, Neo M, Daimon M, Kurisu Y, et al. Bronchogenic cysts in rare sites (retroperitoneum, skin, spinal cord, or pericardial cavity): A case series and characterization of epithelial phenotypes. Biomed Rep. 2024. 20. 2. 21
  • Yamamoto K, Kawabata S, Kurisu Y, Inamoto T, Yamamoto K, Osuga K. A case of renomedullary interstitial cell tumor: Radiologic-pathologic correlation. Radiol Case Rep. 2023. 18. 12. 4574-4579
  • Chang YS, Gills JJ, Kawabata S, Onozawa M, Gatta GD, Ferrando AA, Aplan PD, Dennis PA. Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T-cell acute lymphoblastic leukemia. Int J Oncol. 2023. 63. 5
  • Ishikawa S, Ogihara T, Yamaoka S, Shinohara J, Kawabata S, Hirose Y, Nishioka D, Ashida A. A glucocorticoid-receptor agonist ameliorates bleomycin-induced alveolar simplification in newborn rats. Pediatr Res. 2023. 93. 6. 1551-1558
  • Kimura K, Kawabata S, Oku H, Ikari A, Tominaga T, Takai S, Sakane J, Tanaka M, Aoki C, Ota M, et al. Breast neuroendocrine tumor arising in the axilla of a man: a case report. J Med Case Rep. 2022. 16. 1. 467
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MISC (27)：
  • 三林 聡子, 川畑 茂, 南口 早智子, 海透 修子, 佐々木 瑞希, 長谷川 英男, 森吉 弘毅. 小腸ボルボソーマ感染の一例. 日本病理学会会誌. 2020. 109. 1. 434-434
  • 川畑 茂, 山田 洋介, 橋本 恭一, 羽賀 博典, 山田 泰広. Apc遺伝子変異による細胞種特異的な腫瘍形成. 日本病理学会会誌. 2017. 106. 1. 325-325
  • Atsushi Osoegawa, Joell J. Gills, Shigeru Kawabata, Kenji Sugio, Phillip A. Dennis. Rapamycin sensitizes cancer cells to growth inhibition by the PARP inhibitor olaparib. CANCER RESEARCH. 2014. 74. 19
  • 川畑 茂. 肺癌の動向と研究最前線. さくら通信. 2011. 42:. 2-9,
  • P. A. Dennis, G. Blumenthal, M. Ballas, E. Gardner, S. Kawabata, J. LoPiccolo, C. Helsabeck, H. Root, W. D. Figg, W. Bernstein. A phase I study of nelfinavir, an FDA approved HIV protease inhibitor, in adults with refractory solid tumors. JOURNAL OF CLINICAL ONCOLOGY. 2009. 27. 15. 2583,
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Books (1)：
  • 目でみるトレーニング (岡崎 仁昭 編)
    医学書院. 127-128, 289-290; 2008
Lectures and oral presentations  (7)：
  • The cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior
    (The 106th Annual Meeting of the Japanese Society of Pathology 2017)
  • Rapamycin decreases expression of thymidylate synthase and enhances the response to pemetrexed in preclinical studies and a Phase I/II clinical study of subjects with non-small cell lung cancer
    (AACR Annual Meeting 2014, Minisymposium (San Diego, CA, USA); 2014)
  • Rapamycin prolongs overall survival and progression-free survival in a mouse model of lung cancer in never smokers resistant to erlotinib
    (AACR Annual Meeting 2011, Minisymposium (Orlando, FL, USA); 2011)
  • Tumor stage-specific role of mTOR in a mouse model of lung cancer in never smokers that is resistant to EGFR tyrosine kinase inhibitors
    (NCI Medical Oncology Branch Research Seminar, Seminar series (Bethesda, MD, USA); 2010)
  • Updated Lung Cancer Treatment
    (Omura Medical Association Respiratory Disease Lecture Series 2006)
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Education (3)：
  • 1998 - 2002 Doctor of Philosophy, Nagasaki University Graduate School
  • 1990 - 1996 Doctor of Medicine, Nagasaki University School of Medicine
  • 1984 - 1987 Fukuoka Prefectural Fukuoka High School
Professional career (1)：
  • M.D., Ph.D. (Nagasaki University)
Work history (12)：
  • 2024/03 - 現在 Associate professor, Department of Pathology, Division of Comprehensive Medicine, Faculty of Medicine, Osaka Medical and Pharmaceutical University
  • 2021/04 - 2024/02 Assistant professor, Department of Pathology, Division of Comprehensive Medicine, Faculty of Medicine, Osaka Medical and Pharmaceutical University
  • 2019 - 2021/03 Osaka Medical College Faculty of Medicine Department of Pathology, Division of Comprehensive Medicine Assistant professor
  • 2017 - 2019 National Hospital Organization Kyoto Medical Center Department of Diagnostic Pathology Pathologist
  • 2015 - 2017 Kyoto University Hospital Department of Diagnostic Pathology Resident
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Awards (6)：
  • 2014/07 - Johns Hopkins University (USA) JH Libraries Open Access Promotion Fund
  • 2014/04 - American Association for Cancer Research (AACR) Millennium Scholar-in-Training Award
  • 2013/12 - Johns Hopkins University (USA) The Ruth D. Vogel Professional Development Award
  • 2011/02 - National Institutes of Health (USA) The Visiting Fellow Award, NIH Visiting Program, Department of Health & Human Services Research in lung cell biology and Signal Transduction Research
  • 2009/02 - National Institutes of Health (USA) The Visiting Fellow Award, NIH Visiting Program, Department of Health & Human Services Research in lung cell biology and Signal Transduction Research
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Association Membership(s) (7)：
Board Certification (0028), Molecular Pathology, Japanese Society of Pathology ,  Board Certification (3648), Clinical Cytology, Japanese Society of Clinical Cytology ,  Board Certification (3488), Pathology, Japanese Society of Pathology ,  Certification (9406), Autopsy, the Japanese Ministry of Health, Labour and Welfare ,  Board Certification (7729), Internal Medicine, Japanese Society of Internal Medicine ,  Associate Member (No. 65152), The American Association for Cancer Research ,  Japan Medical Licensing Exam, Medical License (382619), the Japanese Ministry of Health, Labour and Welfare
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