Research keywords (1):
晶構造解析、細胞小器官、ペルオキシソーム、キネトコア、化学架橋質量分析 biochemistry, structural biology, protein complex, membrane protein, X-ray crystallography, organelle, peroxisome, kinetochore, cross-linking mass spectrometry
Research theme for competitive and other funds (3):
2022 - 2025 ペルオキシンリサイクル複合体の構造と制御機構の解明
2020 - 2023 Structural basis for alternating access mechanism of ABC multi-drug pump in lipid membrane
2020 - 2022 Biochemical study of the AAA-ATPase complex in peroxisome protein import
Papers (17):
Yoshiki Inoue, Tomohiro Yamaguchi, Tetsuo Otsuka, Yuto Utsunomiya, Dongqing Pan, Haruo Ogawa, Hiroaki Kato. Structure-based alteration of tryptophan residues of the multidrug transporter CmABCB1 to assess substrate binding using fluorescence spectroscopy. Protein Science. 2022. 31. 6
Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensuke Tono, Eriko Nango, So Iwata, et al. Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX. IUCrJ. 2022. 9. 1. 134-145
Johannes van den Boom, Anja F. Kueck, Bojana Kravic, Helen Müschenborn, Maike Giesing, Dongqing Pan, Farnusch Kaschani, Markus Kaiser, Andrea Musacchio, Hemmo Meyer. Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly. Nature Structural & Molecular Biology. 2021
Kai Walstein, Arsen Petrovic, Dongqing Pan, Birte Hagemeier, Dorothee Vogt, Ingrid R. Vetter, Andrea Musacchio. Assembly principles and stoichiometry of a complete human kinetochore module. Science Advances. 2021. 7. 27. eabg1037-eabg1037
María Ascensión Villar-Fernández, Richard Cardoso da Silva, Magdalena Firlej, Dongqing Pan, Elisabeth Weir, Annika Sarembe, Vivek B Raina, Tanja Bange, John R Weir, Gerben Vader. Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly. Life Science Alliance. 2020. 3. 11. e201900630-e201900630
PAN Dongqing, 筒井隼一, 宮田知子, 牧野文信, 牧野文信, 難波啓一, 小川治夫, 加藤博章, 加藤博章. Cryo-EM single particle analysis of Candida albicans Cdr1p multi-drug ABC transporter. 日本薬学会年会要旨集(Web). 2022. 142nd
水沼諒, PAN Dongqing, 小川治夫, 加藤博章, 加藤博章. The role of multidrug transporter CmABCB1 residues in drug transport based on crystal structure. 日本薬学会年会要旨集(Web). 2022. 142nd