Rchr
J-GLOBAL ID:201901014672989287   Update date: Aug. 26, 2024

Nagaoka So I.

ナガオカ ソウ | Nagaoka So I.
Affiliation and department:
Job title: 助教
Research field  (10): Fetal medicine/Pediatrics ,  Obstetrics and gynecology ,  Laboratory animal science ,  Animal production science ,  Evolutionary biology ,  Genetics ,  Molecular biology ,  Cell biology ,  Genomics ,  Developmental biology
Research keywords  (10): Regenerative medicine ,  Cell division ,  Histone modification ,  Epigenome reprogramming ,  Transcription factor ,  Cell cycle checkpoint ,  Genome structure ,  In vitro oogenesis ,  Meiosis ,  Sex determination
Research theme for competitive and other funds  (14):
  • 2023 - 2026 The next generation oocytology by in vitro gametogenesis technology
  • 2024 - 2025 Drug discovery for fertility expansion via in vitro oocyte derivation technology
  • 2024 - 2025 Drug discovery for fertility expansion via in vitro ovarian organoid
  • 2022 - 2024 The elucidation of oocyte development using in vitro oogenesis technology
  • 2022 - 2023 The elucidation of totipotency acquisition mechanisms by in vitro oogenesis technology
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Papers (19):
  • Eishi Aizawa, Evgeniy A Ozonov, Yumiko K Kawamura, Charles-Etienne Dumeau, So Nagaoka, Tomoya S Kitajima, Mitinori Saitou, Antoine HFM Peters, Anton Wutz. Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes. The EMBO Journal. 2023
  • Hiroki Ikeda, Shintaro Miyao, So Nagaoka, Tomoya Takashima, Sze-Ming Law, Takuya Yamamoto, Kazuki Kurimoto. High-quality single-cell transcriptomics from ovarian histological sections during folliculogenesis. Life science alliance. 2023. 6. 11
  • Eishi Aizawa, Evgeniy A. Ozonov, Yumiko K. Kawamura, Charles-Etienne Dumeau, So Nagaoka, Mitinori Saitou, Antoine H. F. M. Peters, Anton Wutz. Comprehensive comparison of female germ cell developmentin vitroandin vivoidentifies epigenetic gene regulation crucial for oocyte development and embryonic competence. 2023
  • Jacqueline Severino, Moritz Bauer, Tom Mattimoe, Niccolò Arecco, Luca Cozzuto, Patricia Lorden, Norio Hamada, Yoshiaki Nosaka, So I Nagaoka, Pauline Audergon, et al. Controlled X-chromosome dynamics defines meiotic potential of female mouse in vitro germ cells. The EMBO Journal. 2022. 41. 12. e109457
  • Jumpei Taguchi, Hirofumi Shibata, Mio Kabata, Masaki Kato, Kei Fukuda, Akito Tanaka, Sho Ohta, Tomoyo Ukai, Kanae Mitsunaga, Yosuke Yamada, et al. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nature communications. 2021. 12. 1. 5041-5041
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MISC (1):
  • So I. Nagaoka, Kazuki Kurimoto, Mitinori Saitou. ZGLP1 is a determinant for the oogenic fate in mice. Experimental Medicine. 2020. 38. 11. 1893-1896
Lectures and oral presentations  (12):
  • A signaling and transcriptional mechanism for oocyte induction in mice
    (IMEG mini symposium Developmental Biology of Reproduction - Epigenetic, Gene Regulation and Metabolism in Germ Cells - 2023)
  • The elucidation of meiotic regulatory mechanisms using in vitro oogenesis technology
    (2021)
  • Reconstitution of oogenic processes from pluripotent stem cells
    (The 43rd Annual Meeting of the Molecular Biology Society of Japan 2020)
  • A signaling and transcriptional mechanism for the specification of oocytes in mice
    (The 42nd Annual Meeting of the Molecular Biology Society of Japan 2019)
  • ZGLP1 is a determinant for the oogenic fate in mice
    (CiRA International symposium 2019 2019)
more...
Education (3):
  • 2007 - 2012 Washington State University College of Veterinary Medicine School of Molecular Biosciences
  • 2006 - 2007 University of Illinois Urbana-Champaign College of Veterinary Medicine Veterinary Biosciences
  • 2002 - 2005 Washington State University College of Agricultural, Human, and Natural Resource Sciences Department of Animal Sciences
Professional career (1):
  • Ph.D. in Genetics and Cell Biology (Washington State University)
Work history (5):
  • 2020/04 - 現在 Nara Medical University Department of Embryology Assistant Professor
  • 2019/04 - 2020/03 Kyoto University Institute for the Advanced Study of Human Biology (ASHBi) Saitou group Post-doctoral researcher
  • 2016/04 - 2019/03 Kyoto University Department of Anatomy and Cell Biology, Graduate School of Medicine Post-doctoral researcher
  • 2013/04 - 2016/03 Japan Society for the Promotion of Science Recipient laboratory, Kyoto University Graduate School of Medicine, Mitinori Saitou laboratory JSPS Postdoctoral Fellow
  • 2013/03 - 2013/03 Kyoto University Department of Anatomy and Cell Biology, Graduate School of Medicine Post-doctoral researcher
Association Membership(s) (1):
The Molecular Biology Society of Japan
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