Takata Tsuyoshi

タカタツヨシ | Takata Tsuyoshi

Affiliation and department：
Job title：助教

Research field (3)： Molecular biology , Pharmacology , Medical biochemistry

Research theme for competitive and other funds (6)：

2023 - 2026 NADPHオキシダーゼとNO合成酵素による活性硫黄代謝と新しい生理機能の解明
2020 - 2022 パースルフィドによるタンパク質酸化損傷修復メカニズムの解明
2018 - 2020 Novel reactive persulfide-producing system in bacteria and its involvement in bacterial pathogenicity
2018 - 2020 Regulatory mechanism of Ca2+/calmodulin-dependent protein kinase IV by reactive oxygen species
2016 - 2017 Analysis of physiological significance of Ca2+/calmodulin-dependent protein kinase IV inactivation by reactive sulfur species

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Papers (29)：

Akira Nishimura, Sunghyeon Yoon, Tetsuro Matsunaga, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Jun Yoshitake, Yuka Unno, Uladzimir Barayeu, et al. Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality. Redox biology. 2024. 69. 103018-103018
Shoma Araki, Tsuyoshi Takata, Katsuhiko Ono, Tomohiro Sawa, Shingo Kasamatsu, Hideshi Ihara, Yoshito Kumagai, Takaaki Akaike, Yasuo Watanabe, Yukihiro Tsuchiya. Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism. International journal of molecular sciences. 2023. 24. 12
Qamarul Hafiz Zainol Abidin, Tomoaki Ida, Masanobu Morita, Tetsuro Matsunaga, Akira Nishimura, Minkyung Jung, Naim Hassan, Tsuyoshi Takata, Isao Ishii, Warren Kruger, et al. Synthesis of Sulfides and Persulfides Is Not Impeded by Disruption of Three Canonical Enzymes in Sulfur Metabolism. Antioxidants (Basel, Switzerland). 2023. 12. 4
井田智章, Jung Minkyung, 松永哲郎, 守田匡伸, 緒方星陵, 高田剛, 海野雄加, 本橋ほづみ, 赤池孝章. 細菌から動物まで種横断的に保存された超硫黄分子合成経路の発見. 日本細菌学雑誌. 2023. 78. 1. 75-75
ジョン・ミンギョン, 高田剛, 井田智章, 松永哲郎, 守田匡伸, 土屋幸弘, 渡邊泰男, 本橋ほづみ, 住本英樹, 赤池孝章. NADPHオキシダーゼおよび一酸化窒素合成酵素による超硫黄分子活性化と宿主防御機構. 日本細菌学雑誌. 2023. 78. 1. 75-75

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MISC (84)：

佐藤聡, 守田匡伸, JUNG Minkyung, 松永哲郎, 高田剛, 井田智章, 本橋ほづみ, 赤池孝章. Cross-species conservation and generation of knockout mice of sulfurtransferase, Rhodanese. 日本細菌学雑誌(Web). 2022. 77. 1
井田智章, JUNG Minkyung, 西村明, 松永哲郎, 守田匡伸, 高田剛, 本橋ほづみ, 赤池孝章. Supersulfide biosynthesis pathway mediated by aminoacyl-tRNA synthetase in E. coli. 日本細菌学雑誌(Web). 2022. 77. 1
海野雄加, 松永哲郎, 守田匡伸, JUNG Minkyung, 高田剛, 井田智章, 吉沢道人, 本橋ほづみ, 赤池孝章. Supersulfide metabolism regulated by rhodanese in bacteria and mitochondria. 日本細菌学雑誌(Web). 2022. 77. 1
高田剛, 井田智章, 松永哲郎, 守田匡伸, 土屋幸弘, 渡邊泰男, 本橋ほづみ, 吉沢道人, 住本英樹, 赤池孝章. Infection defense through supersulfides production by NADPH oxidase and nitric oxide synthase. 日本細菌学雑誌(Web). 2022. 77. 1
荒木笙馬, 高田剛, 土屋幸弘, 渡邊泰男. Supersulfide regulates calmodulin kinase in a redox cellular signaling-Regulation of phosphorylation signal-. 硫酸と工業. 2022. 75. 3. 29-37

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Professional career (1)：

博士(薬学) (昭和薬科大学)

Work history (4)：

2020/05 - 現在 Tohoku University Graduate School of Medicine Department of Environmental Medicine and Molecular Toxicology, Assistant Professor
2019/08 - 2020/04 Tohoku University Graduate School of Medicine Department of Environmental Medicine and Molecular Toxicology, Postdoctoral Fellow
2019/04 - 2019/07 Tohoku University Graduate School of Medicine Department of Environmental Medicine and Molecular Toxicology, Lecturer
2014/04 - 2019/03 Showa Pharmaceutical University Depertment of Pharmacology Project Assistant Professor

Association Membership(s) (6)：

日本酸化ストレス学会 , 日本細菌学会 , 日本生体防御学会 , NITRIC OXIDE SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY , THE JAPANESE BIOCHEMICAL SOCIETY

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