Satoshi Takagi

タカギサトシ | Satoshi Takagi

Affiliation and department：

Research field (2)： Tumor diagnostics and therapeutics , Tumor biology

Research keywords (5)： Osteosarcoma , Glioblastoma , Platelet , Cancer microenvironment , Cancer metastasis

Research theme for competitive and other funds (11)：

2024 - 2028 Podoplaninを標的としたヒトリンパ管腫(リンパ管奇形)に対する光免疫療法の開発
2023 - 2026 患者由来検体の性状解析に基づく骨肉腫特異的な脆弱性の基盤解析
2023 - 2025 Therapeutic strategies targeting LPA receptors in osteosarcoma and rare cancers
2021 - 2023 Therapeutic strategies targeting lipid mediator receptors in osteosarcoma proliferation and metastasis
2017 - 2022 Integrated analysis and regulation of cellular diversity for disease treatment

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Papers (39)：

Xinzhao Wei, Ken Uchibori, Nobuyuki Kondo, Takahiro Utsumi, Ai Takemoto, Sumie Koike, Satoshi Takagi, Noriko Yanagitani, Makoto Nishio, Ryohei Katayama. MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer. Cancer Letters. 2024
Kohei Otomo, Takaki Omura, Yuki Nozawa, Steven J Edwards, Yukihiko Sato, Yuri Saito, Shigehiro Yagishita, Hitoshi Uchida, Yuki Watakabe, Kiyotada Naitou, et al. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques. Nature communications. 2024. 15. 1. 4941-4941
Mizuki Haraguchi, Kazuma Kiyotani, Tomohiro Tate, Seiji Sakata, Ray Sagawa, Satoshi Takagi, Satoshi Nagayama, Kengo Takeuchi, Kazuhisa Takahashi, Ryohei Katayama. Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer. Cancer immunology, immunotherapy : CII. 2023. 72. 9. 2971-2989
Takuya Sakashita, Noriko Yanagitani, Sumie Koike, Siew-Kee Low, Satoshi Takagi, Satoko Baba, Kengo Takeuchi, Makoto Nishio, Naoya Fujita, Ryohei Katayama. Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK -rearranged non-small cell lung cancer. Cancer Science. 2022. 113. 11. 3888-3900
Ai Takemoto, Satoshi Takagi, Takao Ukaji, Nobuhiko Gyobu, Mamoru Kakino, Miho Takami, Asami Kobayashi, Marie Lebel, Tokuichi Kawaguchi, Minoru Sugawara, et al. Targeting Podoplanin for the Treatment of Osteosarcoma. Clinical Cancer Research. 2022. 28. 12. OF1-OF13

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MISC (7)：

高木聡, 藤田直也. 【がん微小環境に1細胞レベルで挑む技術革新で見えてきた腫瘍内の細胞と免疫応答の多様性、がん悪性化・治療抵抗性の鍵】(第1章)がん幹細胞を支えるがん微小環境の多様性血小板との相互作用が促進するがんの悪性化とその制御. 実験医学. 2021. 39. 12. 1869-1874
塚本祥吉, 高木聡, Park Jihye, Johnson Kelly E, 河野和, Moschetta Michele, Liu Chia-Jen, 三嶋雄二, 國分克寿, Manier Salomon, et al. 分子病態の解明血小板はIL-1βを介して多発性骨髄腫の病勢進行に寄与している. International Journal of Myeloma. 2018. 8. 2. 82-82
Tsukamoto Shokichi, Loevendori Marianne B., Park Jihye, Salem Karma Z., Manier Salomon, Reagan Michaela R., Zavidij Oksana, Rahmat Mahshid, Takagi Satoshi, Kawano Yawara, et al. 多発性骨髄腫の間質細胞においてmicroRNA-138の抑制は骨細胞分化を促進する(Inhibition of microRNA-138 promotes osteogenic differentiation in stromal cells in multiple myeloma). 臨床血液. 2017. 58. 9. 1460-1460
Yuji Mishima, Jiantao Shi, Michele Moschetta, Yujia Shen, Salomon Manier, Aldo M. Roccaro, Francois Mercier, Satoshi Takagi, Yawara Kawano, Shokichi Tsukamoto, et al. In Vivo Analysis of Clonal Evolution of Multiple Myeloma. BLOOD. 2016. 128. 22
Antonio Sacco, Yawara Kawano, Michele Moschetta, Jihye Park, Oksana Zavidij, Michaela Reagan, Yuji Mishima, Elizabeth A. Morgan, Satoshi Takagi, Salomon Manier, et al. Dual Conditional Loss of BLIMP-1 and p53 in B-Cells Drives B-Cell Lymphomagenesis. BLOOD. 2016. 128. 22

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Patents (3)：

Education (3)：

2006 - 2009 Saitama University Graduate School of Science and Engineering
2004 - 2006 Hosei University
2000 - 2004 Hosei University Faculty of Engineering Department of Materials Chemistry

Professional career (1)：

博士(理学) (埼玉大学大学院)

Work history (6)：

2018/04 - 現在 Japanese Foundation for Cancer Research Div. of Experimental Chemotherapy, Cancer Chemotherapy Center Staff Scientist
2016/02 - 2018/03 文部科学省研究振興局研究振興戦略官付文部科学省調査員
2014/05 - 2016/01 Harvard Medical School/Dana-Farber Cancer Institute Medical Oncology, Ghobrial Lab Research Fellow
2010/04 - 2014/04 財団法人癌研究会癌化学療法センター基礎研究部特任研究員
2009/04 - 2010/03 理化学研究所長田抗生物質研究室ポスドク

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Committee career (2)：

2023/06 - 2026/06 日本がん分子標的治療学会評議員
2023/01 - 2025/12 日本癌学会評議員

Awards (5)：

2024/06 - 第6回血管生物医学会若手研究会優秀賞
2023/08 - 内閣府健康・医療戦略推進事務局第6回日本医療研究開発大賞日本医療研究開発機構(AMED)理事長賞
2022/07 - 日本がん転移学会第26回研究奨励賞
2021/05 - 第25回日本がん分子標的治療学会優秀演題賞
2021/05 - 日本がん分子標的治療学会 2020年度研究奨励賞

Association Membership(s) (4)：

American Association for Cancer Research , 日本がん転移学会 , 日本がん分子標的治療学会 , 日本癌学会

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