Yu Kitago

キタゴウユウ | Yu Kitago

Affiliation and department：
Homepage URL (1)： https://petskolab.bwh.harvard.edu/

Research field (2)： Structural biochemistry , Molecular biology

Research keywords (5)： Cell Biology , Alzheimer's Disease , X-ray crystallography , Structural Biology , Protein Science

Research theme for competitive and other funds (3)：

2017 - 2018 Protein binder screening for SorLA, a risk factor of Alzheimer's diesease, to identify novel targets for drug dicovery(Fostering Joint International Research)
2014 - 2017 Structural elucidation of a risk factor for Alzheimer's Disease, sorLA extracellular region
2012 - 2017 Structural basis for the cell-cell communication at the neuro-immune interface

Papers (23)：

Anne Mette G Jensen, Yu Kitago, Elnaz Fazeli, Christian B Vægter, Scott A Small, Gregory A Petsko, Olav M Andersen. Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association with retromer. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 4. e2212180120
Masamichi Nagae, Yasuhiko Kizuka, Emiko Mihara, Yu Kitago, Shinya Hanashima, Yukishige Ito, Junichi Takagi, Naoyuki Taniguchi, Yoshiki Yamaguchi. Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V. Nature communications. 2018. 9. 1. 3380-3380
Sanae Tabata, Yu Kitago, Yuki Fujii, Emiko Mihara, Keiko Tamura-Kawakami, Naoko Norioka, Katsu Takahashi, Mika K. Kaneko, Yukinari Kato, Junichi Takagi. An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system. Protein Expression and Purification. 2018. 147. 94-99
Takao Arimori, Yu Kitago, Masataka Umitsu, Yuki Fujii, Ryoko Asaki, Keiko Tamura-Kawakami, Junichi Takagi. Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability. STRUCTURE. 2017. 25. 10. 1611-+
Mamoru Takizawa, Takao Arimori, Yukimasa Taniguchi, Yu Kitago, Erika Yamashita, Junichi Takagi, Kiyotoshi Sekiguchi. Mechanistic basis for the recognition of laminin-511 by alpha 6 beta 1 integrin. SCIENCE ADVANCES. 2017. 3. 9. e1701497

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MISC (39)：

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Patents (1)：

Education (3)：

2005 - 2008 Hokkaido University Department of Biological Science, Graduate School of Science
2003 - 2005 Hokkaido University Department of Biological Science, Graduate School of Science
1999 - 2003 Hokkaido University Faculty of Science

Professional career (1)：

Work history (7)：

2021/06 - 現在 Harvard Medical School and Brigham & Women's Hospital Ann Romney Center for Neurologic Diseases Postdoctoral Research Fellow
2012/04 - 2021/06 Osaka University Laboratory of Protein Synthesis and Expression, Institute for Protein Research Assistant Professor
2017/12 - 2018/11 Weill Cornell Medicine Feil Family Brain and Mind Research Institute Visiting Fellow
2012/02 - 2012/03 大阪大学蛋白質研究所附属プロテオミクス総合研究センター,プロテオーム物質創製研究系
2011/04 - 2012/01 Osaka University Laboratory of Protein Synthesis and Expression, Institute for Protein Research Postdoctroal Fellow

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Association Membership(s) (2)：

THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN , PROTEIN SCIENCE SOCIETY OF JAPAN

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