Rchr
J-GLOBAL ID:201901015182245219   Update date: Oct. 19, 2024

Tarutani Airi

Tarutani Airi
Affiliation and department:
Job title: Researcher
Research field  (3): Neuropathology ,  Experimental pathology ,  Pathobiochemistry
Research keywords  (6): 神経変性疾患 ,  構造多型 ,  アミロイド ,  プリオン様伝播 ,  タウ ,  αシヌクレイン
Research theme for competitive and other funds  (4):
  • 2020 - 2022 異常タンパク質のプリオン様性質を決定する非タンパク質性コファクターの探索
  • 2018 - 2020 大脳皮質基底核変性症の細胞、動物モデルの研究
  • 2014 - 2019 Molecular bases of pathogenic proteins and mechanisms of the propagation
  • 2018 - 2019 異常型αシヌクレインの多様な高次構造は疾患特異的な病態を引き起こすか?
Papers (26):
  • Akira Arakawa, Shigeo Murayama, Satoru Morimoto, Tomoyasu Matsubara, Renpei Sengoku, Masashi Kameyama, Aya M Tokumaru, Airi Tarutani, Masato Hasegawa, Atsushi Iwata, et al. A case of argyrophilic grain disease with an initial clinical diagnosis of Parkinson's disease. Journal of neurology. 2024
  • Anthony Aggidis, George Devitt, Yongrui Zhang, Shreyasi Chatterjee, David Townsend, Nigel J Fullwood, Eva Ruiz Ortega, Airi Tarutani, Masato Hasegawa, Amber Cooper, et al. A novel peptide-based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024
  • Airi Tarutani, Masato Hasegawa. Ultrastructures of α-Synuclein Filaments in Synucleinopathy Brains and Experimental Models. Journal of movement disorders. 2024. 17. 1. 15-29
  • Reito Nakamura, Ikumi Tomizawa, Atsushi Iwai, Tetsuo Ikeda, Kota Hirayama, Yung Wen Chiu, Takanobu Suzuki, Airi Tarutani, Tatsuo Mano, Atsushi Iwata, et al. Photo-oxygenation of histidine residue inhibits α-synuclein aggregation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 12. e23311
  • Airi Tarutani, Fuyuki Kametani, Marina Tahira, Yuko Saito, Mari Yoshida, Andrew C Robinson, David M A Mann, Shigeo Murayama, Taisuke Tomita, Masato Hasegawa. Distinct tau folds initiate templated seeding and alter the post-translational modification profile. Brain. 2023
more...
MISC (17):
  • 樽谷愛理, 長谷川成人. Structural and biochemical classification of tauopathies. 医学のあゆみ. 2023. 287. 13
  • 樽谷愛理, 長谷川成人. 変性疾患 1 クライオ電子顕微鏡によるタウタンパクの構造解析診断での有用性. Annual Review 神経. 2023. 2023
  • 樽谷愛理, 長谷川成人. Biochemical and structural classification of human tauopathies. Bio Clinica. 2023. 38. 3
  • 平山皓太, 鵜川佑太, LIU Yanchen, 樽谷愛理, 富田泰輔. トレハロースによるαシヌクレイン凝集への寄与の検討. Dementia Japan. 2022. 36. 4
  • 樽谷愛理, 樽谷愛理, FERNANDEZ-BUSNADIEGO Ruben. Understanding the pathogenesis of neurodegenerative diseases by cryo-electron tomography. 医学のあゆみ. 2022. 283. 13
more...
Lectures and oral presentations  (11):
  • Molecular understanding of pathogenic proteins in neurodegenerative diseases using cryogenic electron microscopy
    (2023)
  • Classification of tauopathies based on tau filament structure
    (The 64th Annual Meeting of the Japanese Society of Neurology 2023)
  • Prion-like propagation of α-synuclein in neurodegenerative diseases
    (Yonsei University 2023)
  • Biochemical classification of alpha-synuclein strains in PD, MSA and DLB.
    (The 11th Yonsei Parkinson Center Symposium 2023)
  • Structural polymorphisms of tau filaments contribute to the diversity of tauopathies
    (The 63th Annual Meeting of the Japanese Society of Neuropathology 2022)
more...
Professional career (1):
  • 博士(理学) (首都大学東京大学院)
Awards (4):
  • 2023/04 - 公益社団法人日本生化学会 早石修記念海外留学助成
  • 2022/04 - 公益財団法人細胞科学研究財団 令和四年度育成助成
  • 2022/04 - 公益財団法人山田科学振興財団 海外研究援助(個人B)
  • 2021/04 - 公益財団法人上原記念生命科学財団 海外留学助成リサーチフェローシップ 神経変性疾患の病態進行に関するプリオン様伝播の研究
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