Rchr
J-GLOBAL ID：201901015442617786
Update date: Aug. 26, 2024
Okuyama Yuko
オクヤマ ユウコ | Okuyama Yuko
Affiliation and department：
Research field (1)：
Immunology
Research theme for competitive and other funds (4)：
- 2020 - 2023 TNF受容体型補助刺激分子による自然リンパ球の制御機構
- 2017 - 2020 GITR signaling regulates ILC2 function
- 2015 - 2018 Regulation of inflammatory cytokine signaling by TRAF5
- 2015 - 2017 IQGAP1 regulates OX40 costimulatory signaling in CD4+ T cells
Papers (25)：
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Eigo Kawahara, Mitsuki Azuma, Hiroyuki Nagashima, Koki Omori, Sho Akiyama, Yuka Fujimori, Mayu Oishi, Nagito Shibui, Kosuke Kawaguchi, Masashi Morita, et al. TNF Receptor-Associated Factor 5 Limits IL-27 Receptor Signaling in CD4+ T Lymphocytes. Journal of immunology (Baltimore, Md. : 1950). 2022. 208. 3. 642-650
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Tetsuya Niihori, Reo Tanoshima, Yoji Sasahara, Atsushi Sato, Masahiro Irie, Yuka Saito-Nanjo, Ryo Funayama, Matsuyuki Shirota, Taiki Abe, Yuko Okuyama, et al. Phenotypic heterogeneity in individuals with MECOM variants in 2 families. Blood advances. 2022. 6. 18. 5257-5261
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Ayaka Sato, Mitsuki Azuma, Hodaka Nagai, Wakana Imai, Kosuke Kawaguchi, Masashi Morita, Yuko Okuyama, Naoto Ishii, Takanori So. OX40 Ligand-Mannose-Binding Lectin Fusion Protein Induces Potent OX40 Cosignaling in CD4+ T Cells. Biological & pharmaceutical bulletin. 2022. 45. 12. 1798-1804
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Ryosuke Tashiro, Kuniyasu Niizuma, Jun Kasamatsu, Yuko Okuyama, Sherif Rashad, Atsuo Kikuchi, Miki Fujimura, Shigeo Kure, Naoto Ishii, Teiji Tominaga. Dysregulation of Rnf 213 gene contributes to T cell response via antigen uptake, processing, and presentation. Journal of cellular physiology. 2021. 236. 11. 7554-7564
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Tsuyoshi Sakurai, Yuko Okuyama, Shuhei Kobayashi, Hai The Phung, Atsuko Asao, Takeshi Kawabe, Lishomwa C Ndhlovu, Carlo Riccardi, Hironori Kudo, Motoshi Wada, et al. GITR controls intestinal inflammation by suppressing IL-15-dependent NK cell activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 11. 14820-14831
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MISC (11)：
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河原永悟, 東充輝, 秋山晟, 藤森由夏, 大石真結, 渋井凪人, 川口甲介, 守田雅志, 奥山祐子, 石井直人, et al. Traf5-deficiency promotes T-helper cell type 1 development mediated by IL-27. 日本薬学会年会要旨集(Web). 2022. 142nd
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河原永悟, 藤森由夏, 大石真結, 川口甲介, 守田雅志, 奥山祐子, 石井直人, 宗孝紀. Elucidation of regulatory mechanisms of IL-27 receptor signaling mediated by TRAF5 in CD4+ T cells. 日本薬学会年会要旨集(Web). 2021. 141st
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藤森由夏, 河原永悟, 川口甲介, 守田雅志, 帯田孝之, 奥山祐子, 水口峰之, 石井直人, 宗孝紀. サイトカイン受容体gp130とTRAFタンパク質の相互作用様式の解明. 日本薬学会北陸支部例会/日本病院薬剤師会北陸ブロック学術大会プログラム集&要旨集(Web). 2019. 131st-30th
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河原永悟, 藤森由夏, 大石真結, 川口甲介, 守田雅志, 奥山祐子, 石井直人, 宗孝紀. CD4陽性T細胞のIL-27受容体シグナルにおけるTRAF5の抑制性機能の解明. 日本薬学会北陸支部例会/日本病院薬剤師会北陸ブロック学術大会プログラム集&要旨集(Web). 2019. 131st-30th
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H. Nagashima, Y. Okuyama, T. Hayashi, A. Asao, T. Kawabe, S. Yamaki, H. Nakano, M. Croft, N. Ishii, T. So. CD4(+) T cell-intrinsic TRAF5 negatively regulates Th17 cell-dependent experimental autoimmune encephalomyelitis. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 869-869
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Professional career (1)：
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