Rchr
J-GLOBAL ID：201901015496425696   Update date: Aug. 20, 2022

Baba Osamu

ババ オサム | Baba Osamu
Affiliation and department：
Kyoto University

About Kyoto University


Research field  (1)： Cardiology
Research keywords  (4)： ケモカイン受容体 ,  マクロファージ ,  PET ,  動脈硬化
Research theme for competitive and other funds  (5)：
  • 2022 - 2025 Elucidation of the function of CXCR7 on atherosclerosis and its clinical application by PET imaging
  • 2020 - 2022 CCR2特異的新規PETトレーサーを用いた動脈硬化の病態解明およびその臨床応用
  • 2021 - 2022 Elucidating the pathology of atherosclerosis by CXCR7 specific PET tracer
  • 2020 - 2021 CCR2特異的PETトレーサーを用いた動脈硬化の病態解明およびその臨床応用
  • 2015 - 2017 マイクロRNA-33の骨髄機能および慢性炎症における役割の検討
Papers (63)：
  • Tomohiro Yamasaki, Takahiro Horie, Satoshi Koyama, Tetsushi Nakao, Osamu Baba, Masahiro Kimura, Naoya Sowa, Kazuhisa Sakamoto, Kazuhiro Yamazaki, Satoshi Obika, et al. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways. Scientific Reports. 2022. 12. 1
  • Koh Ono, Satoshi Shizuta, Erika Yamamoto, Naritatsu Saito, Neiko Ozasa, Takao Kato, Eri Kato, Takahiro Horie, Junichi Tazaki, Hiroki Shiomi, et al. Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society - Change Practice!. Circulation journal : official journal of the Japanese Circulation Society. 2021. 85. 3. 323-329
  • Takahiro Horie, Tetsushi Nakao, Yui Miyasaka, Tomohiro Nishino, Shigenobu Matsumura, Fumiko Nakazeki, Yuya Ide, Masahiro Kimura, Shuhei Tsuji, Randolph Ruiz Rodriguez, et al. microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity. Nature communications. 2021. 12. 1. 843-843
  • Osamu Baba, Li-Hao Huang, Andrew Elvington, Martyna Szpakowska, Deborah Sultan, Gyu Seong Heo, Xiaohui Zhang, Hannah Luehmann, Lisa Detering, Andy Chevigne, et al. CXCR4-Binding Positron Emission Tomography Tracers Link Monocyte Recruitment and Endothelial Injury in Murine Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology. 2021. 41. 2. 822-836
  • Koh Ono, Takahiro Horie, Osamu Baba, Masahiro Kimura, Shuhei Tsuji, Randolph Ruiz Rodriguez, Sawa Miyagawa, Takeshi Kimura. Functional non-coding RNAs in vascular diseases. The FEBS journal. 2020
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MISC (23)：
  • Masataka Nishiga, Takahiro Horie, Yasuhide Kuwabara, Osamu Baba, Tetsushi Nakao, Tomohiro Nishino, Daihiko Hakuno, Yasuhiro Nakashima, Kazuya Nagao, Koji Hasegawa, et al. MicroRNA-33 Maintains Cellular Cholesterol Content in Fibroblasts and Fibrotic Response in Heart. CIRCULATION. 2016. 134
  • Yasuhide Kuwabara, Takahiro Horie, Osamu Baba, Masataka Nishiga, Tetsushi Nakao, Tomohiro Nishino, Fumiko Nakazeki, Satoshi Koyama, Takeshi Kimura, Koh Ono. Overexpression of the lincRNA Regulated by Pressure-Overload Leads to Cardiomyocyte Hypertrophy. JOURNAL OF CARDIAC FAILURE. 2016. 22. 9. S206-S206
  • Satoshi Koyama, Takashi Kuragaichi, Yukihito Sato, Yasuhide Kuwabara, Takahiro Horie, Osamu Baba, Takeshi Kimura, Koh Ono. Changes and Physiological Meanings of Serum microRNA during Therapeutic Course of Acute Heart Failure. JOURNAL OF CARDIAC FAILURE. 2016. 22. 9. S178-S179
  • Yasuhide Kuwabara, Takahiro Horie, Shin Watanabe, Osamu Baba, Takeshi Kimura, Koh Ono. Long Intergenic Noncoding RNA and Myogenin Circuitry Promotes Myoblast Differentiation. Keystone Symposia, Noncoding RNAs in Health and Disease. 2016
  • 堀江貴裕, 西野共達, 馬場理, 桑原康秀, 木村剛, 尾野亘. マイクロRNA-33を介した新たな脂質代謝制御機構の解明. 血管. 2016. 39. 1. 30
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Lectures and oral presentations  (6)：
  • The CCR2 targeting peptide-based PET tracer, 64Cu-DOTA-ECL1i can non-invasively visualize monocytes and inflammatory macrophages in atherosclerotic plaque
    (Cardiovascular And Metabolic Week 2021(CVMW2021) 2021)
  • The CCR2 targeting peptide-based PET tracer, 64Cu-DOTA-ECL1i can non-invasively visualize monocytes and inflammatory macrophages in atherosclerotic plaque
    (The 19th International Symposium on Atherosclerosis(ISA2021) 2021)
  • The CCR2 targeting peptide-based PET tracer, 64Cu-DOTA-ECL1i can non-invasively visualize monocytes and inflammatory macrophages in atherosclerotic plaque
    (2020)
  • CXCR4 on Atherosclerotic Plaque Endothelium Predicts the Magnitude of Monocyte Recruitment and is Readily Targeted by PET Tracers
    (2020)
  • (2) CXCR4 on aortic endothelium can be a novel marker of atherosclerosis activity detected by 64Cu-DOTA-vMIP-II PET tracer
    (2019)
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Education (2)：
  • 2010 - 2014 Kyoto University Graduate School of Medicine Graduate School of Medicine
  • 1997 - 2003 Kyoto University Faculty of Medicine Department of Medical Science
Work history (7)：
  • 2019/09 - 現在 Kyoto University Hospital
  • 2016/07 - 2019/08 Washington University School of Medicine in St. Louis Department of Pathology and Immunology Postdoctoral Associate
  • 2015/04 - 2016/06 Kyoto University Hospital
  • 2014/04 - 2015/03 Kyoto University Faculty of Medicine
  • 2006/04 - 2010/03 市立岸和田市民病院 循環器内科 医師
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Awards (2)：
  • 2015 - 公益財団法人万有生命科学振興国際交流財団 海外留学助成
  • 2014 - 日本心臓財団・アステラス・ファイザー「動脈硬化Update」研究助成 奨励研究 マイクロRNA-33の骨髄機能および慢性炎症における役割の検討
Association Membership(s) (2)：
日本循環器学会 ,  日本内科学会
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