Rchr
J-GLOBAL ID：201901015829235520
Update date: Jan. 30, 2024
Tsuji Mieko
ツジ ミエコ | Tsuji Mieko
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (2)：
- 2019 - 2023 Development of novel boron carrier utilizing amino acid transporters specific for glutamine addiction of cancer cells
- 2016 - 2019 Development of tumor-selective drug based on synthetic lethal strategy by overcoming oxidative stress tolerance of cancer
Papers (10)：
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Takumi Kariya, Hayato Hasegawa, Taro Udagawa, Yusaku Inada, Kyoko Nishiyama, Mieko Tsuji, Tasuku Hirayama, Tatsuo Suzutani, Naoki Kato, Shingo Nagano, et al. Elucidation of the stereocontrol mechanisms of the chemical and biosynthetic intramolecular Diels-Alder cycloaddition for the formation of bioactive decalins. RSC advances. 2023. 13. 40. 27828-27838
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Tsuyoshi Tahara, Shuhei Takatani, Mieko Tsuji, Nina Shibata, Nami Hosaka, Michiko Inoue, Masahiro Ohno, Daiki Ozaki, Aya Mawatari, Yasuyoshi Watanabe, et al. Characteristic Evaluation of a 11C-Labeled Leucine Analog, l-α-[5-11C]methylleucine, as a Tracer for Brain Tumor Imaging by Positron Emission Tomography. Molecular pharmaceutics. 2023. 20. 3. 1842-1849
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Mieko Tsuji, Haruno Taira, Taro Udagawa, Tatsuya Aoki, Tasuku Hirayama, Hideko Nagasawa. Synthesis and photochemical properties of caged peroxides for photocontrol of cellular oxidative stress. Chemical Communications. 2023
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Naho Minegaki, Tetsuo Koshizuka, Kouki Hatasa, Hiroki Kondo, Hiroki Kato, Miyu Tannaka, Keita Takahashi, Mieko Tsuji, Naoki Inoue. The C-Terminal Penta-Peptide Repeats of Major Royal Jelly Protein 3 Ameliorate the Progression of Inflammation in Vivo and in Vitro. Biological & pharmaceutical bulletin. 2022. 45. 5. 583-589
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Shuhei Takatani, Tsuyoshi Tahara, Mieko Tsuji, Daiki Ozaki, Nina Shibata, Yoshinobu Hashizume, Masaaki Suzuki, Hirotaka Onoe, Yasuyoshi Watanabe, Hisashi Doi. Synthesis of L-[5-11 C]Leucine and L-α-[5-11 C]Methylleucine via Pd0 -mediated 11 C-Methylation and Microfluidic Hydrogenation: Potentiality of Leucine PET Probes for Tumor Imaging. ChemMedChem. 2021
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MISC (4)：
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松下明香里, 辻美恵子, 真田悠生, 平山祐, 増永慎一郎, 永澤秀子. Development of new boron carriers for BNCT targeting amino acid transporters. KURNS-EKR (Web). 2021. 10
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Development of Peptide-conjugated Boron Carriers for Boron Neutron Capture Therapy. 2016. 67. 11. 845-852
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Mieko Tsuji, Satoshi Ueda, Tasuku Hirayama, Kensuke Okuda, Yoshiaki Sakaguchi, Aoi Isono, Hideko Nagasawa. FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes (vol 11, pg 3030, 2013). ORGANIC & BIOMOLECULAR CHEMISTRY. 2013. 11. 48. 8510-8510
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Tsuji M, Masunaga S, Okuda K, Hirayama T, Nagasawa H. Development of Direct Intra-Cellular Drug Delivery System Based on Lipidated Peptides, Pepducins. Progress Report 2012, The Research Reactor Institute, Kyoto University. 2013. 149
Education (2)：
- 2008 - 2013 Gifu Pharmaceutical university
- 2004 - 2008 Gifu Pharmaceutical university
Work history (4)：
- 2016/11 - 現在 Gifu Pharmaceutical University
- 2015/11 - 2016/10 乙卯研究所 研究員
- 2014/04 - 2015/10 理化学研究所イメージングセンター 標識化学チーム 特別研究員
- 2013/04 - 2014/04 理化学研究所イメージングセンター 標識化学チーム リサーチアソシエイト
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