Rchr
J-GLOBAL ID:201901016035073298   Update date: Nov. 06, 2024

Kunihiro Otsuka

オオツカ クニヒロ | Kunihiro Otsuka
Affiliation and department:
Job title: Assistant Professor
Other affiliations (3):
  • The University of Tokushima  Division of Interdisciplinary Researches for Medicine and Photonics   Assistant Professor
  • The University of Tokushima
  • The University of Tokushima
Homepage URL  (2): http://immunology.hosp.med.tokushima-u.ac.jp/immunology/system/top/https://ishimarun.wixsite.com/oralpathol
Research field  (4): Oral medicine (pathology) ,  Oral medicine ,  Immunology ,  Experimental pathology
Research keywords  (8): Sjögren's syndrome ,  autoimmune disease ,  Salivary gland ,  Immunopathology ,  Pathology ,  single cell RNA-seq ,  single cell spatial analysis ,  医光融合
Research theme for competitive and other funds  (10):
  • 2023 - 2027 Novel pathogenesis and therapeutic strategy of autoimmunity based on immune-tuning molecules
  • 2023 - 2026 CD153-CD30相互作用を介したシェーグレン症候群の新たな発症機序の解明
  • 2023 - 2025 Clinical application based on the molecular mechanism of autoantibody production in autoimmunity
  • 2019 - 2024 Analysis of Pathogenesis of Autoimmunity through Communication between Organs
  • 2020 - 2023 Investigation of the pathogenesis of Sjögren's syndrome based on single-cell RNA sequencing
Show all
Papers (49):
  • Hiroaki Tawara, Takaaki Tsunematsu, Shojiro Kitajima, Ruka Nagao, Shigefumi Matsuzawa, Kunihiro Otsuka, Aya Ushio, Naozumi Ishimaru. The noncanonical function of borealin, a component of chromosome passenger complex, promotes glycolysis via stabilization of survivin in squamous cell carcinoma cells. Biochemical and biophysical research communications. 2024. 706. 149741-149741
  • 常松 貴明, 吉川 治孝, 永尾 瑠佳, 松澤 鎮史, 大塚 邦紘, 牛尾 綾, 石丸 直澄. がん特殊化リボソームの同定と機能解析(Identification and characterization of cancer-specialized ribosomes). 日本病理学会会誌. 2024. 113. 1. 295-295
  • 俵 宏彰, 常松 貴明, 永尾 瑠佳, 松澤 鎮史, 大塚 邦紘, 牛尾 綾, 石丸 直澄. Borealin-Survivin複合体は頭頸部扁平上皮癌の分化を直接的に制御する(Borealin-Survivin complex directly regulates keratinocyte differentiation in HNSCC). 日本病理学会会誌. 2024. 113. 1. 296-296
  • 永尾 瑠佳, 山本 安希子, 牛尾 綾, 大塚 邦紘, 松澤 鎮史, 常松 貴明, 石丸 直澄. シェーグレン症候群の病態形成に対するT細胞の共抑制性受容体の役割の解析(Analysis of the role of co-inhibitory receptors on T cells to the pathogenesis of Sjogren's syndrome). 日本病理学会会誌. 2024. 113. 1. 297-297
  • 松澤 鎮史, 牛尾 綾, 永尾 瑠佳, 大塚 邦紘, 俵 宏彰, 常松 貴明, 石丸 直澄. 新生児期の胸腺におけるオートファジーとシェーグレン症候群の関係性(The relationship between autophagy in the neonatal thymus and Sjogren syndrome). 日本病理学会会誌. 2024. 113. 1. 333-333
more...
MISC (92):
  • 大塚 邦紘, 石丸 直澄. 特集 Sjögren症候群の最近の知見 総説2 Sjögren症候群の病理. 皮膚病診療. 2024. 46. 9. 788-793
  • Naozumi Ishimaru, Kunihiro Otsuka, Takaaki Tsunematsu, Yuhji Taquahashi, Jun Kanno. 149 Chronic Immunotoxicity of Multi-Walled Carbon Nanotubes on Macrophages via MMP-12. Annals of Work Exposures and Health. 2023. 67. Supplement_1. i74-i74
  • 俵宏彰, 常松貴明, 永尾瑠佳, 福田一稀, 佐藤真美, 大塚邦紘, 牛尾綾, 石丸直澄. 頭頸部扁平上皮癌における染色体パッセンジャー複合体構成因子Borealinの高発現がもたらす新たな役割. 口腔組織培養学会誌. 2023. 32. 1
  • 牛尾綾, LENNIKOV Mami, 大塚邦紘, 常松貴明, 石丸直澄, 高濱洋介. The layer protection of heterogeneous medullary thymic epithelial cells for autoimmune disease. 日本病理学会会誌. 2023. 112. 1
  • 大塚邦紘, 大塚邦紘, 大塚邦紘, 近藤博之, 九十九伸一, 九十九伸一, 新垣理恵子, 永尾瑠佳, 佐藤真美, 牛尾綾, et al. CD153-CD30 axis contributes to the autoimmune pathology in salivary glands of Sjogren’s syndrome. 日本病理学会会誌. 2023. 112. 1
more...
Lectures and oral presentations  (58):
  • Salivary gland fibroblasts drive autoimmune pathology via the interaction with CD4+ T cells in Sjögren’s syndrome
    (2024)
  • The Influence of Obesity and Aging on ADAM17 Expression in Salivary Glands and the Therapeutic Potential of Metformin
    (2024)
  • T 細胞と線維芽細胞の相互作用による自己免疫疾患の増悪機構
    (第131回 蔵本免疫懇話会 2024)
  • The interplay between CD4 T cells and fibroblasts in salivary glands drives autoimmune pathology in Sjögren’s syndrome
    (11th International Conference on Autoimmunity: Mechanisms and Novel Treatments)
  • 線維芽細胞を介した自己免疫病変の増悪機構
    (第32回日本シェーグレン症候群学会学術集会 2024)
more...
Education (2):
  • 2015 - 2019 Tokushima University Graduate School of Oral Sciences, Oral Molecular Pathology
  • 2008 - 2014 Tokushima University Faculty of Dentistry School of Dentistry
Professional career (1):
  • DDS, Ph.D. (Tokushima University)
Work history (4):
  • 2021/04 - 現在 徳島大学病院 助教
  • 2021/04 - 現在 徳島大学ポストLEDフォトニクス研究所 医光融合研究部門 助教 (併任)
  • 2019/04 - 2021/03 Institute of Post-LED Photonics, Tokushima University Department of Interdisciplinary Researches for Medicine and Photonics Designated Assistant Professor
  • 2014/04 - 2015/03 鉄蕉会 亀田総合病院 歯科研修医
Awards (7):
  • 2022/09 - 3学会合同学術大会 (第32回日本口腔内科学会 ・第33回日本臨床口腔病理学会 ・第35回日本口腔診断学会) 一般演題 大会長賞
  • 2020/09 - Encouragement award from Japanese Society for Sjögren’s syndrome
  • 2020/08 - 日本臨床口腔病理学会 学術奨励賞 (実験病理部門)
  • 2018/08 - 先端歯学国際研究ネットワーク・先端歯学スクール 最優秀賞
  • 2018/08 - 一般財団法人岩垂育英会奨学生
Show all
Association Membership(s) (6):
Japanese Association for Oral Biology ,  Shikoku Society of Dental Research ,  Japanese Society for Sjögren’s syndrome ,  the Japanese Society of Oral Pathology (JSOP) ,  Japanese Society for Immunology ,  The Japanese Society of Pathology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page