Oka Akira

オカアキラ | Oka Akira

Affiliation and department：

Research field (1)： Genetics

Research theme for competitive and other funds (16)：

2019 - 2022 Functional analysis of RXRB genetically identified as a susceptibility gene for systemic sclerosis
2017 - 2020 Identification for susceptibility genes of mandibular pragmatism from the results of next-generation sequencing
2016 - 2019 Identification of eating disorder susceptibility variants by whole-exome sequencing
2016 - 2019 Elucidation of pathophysiology for development of new hypertension gene ATP2B1 and carotid atherosclerosis and development of treatment strategy
2016 - 2019 Identification of alopecia areata gene by GWAS (3rd stage)

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Papers (94)：

Akira Oka, Shinji Hadano, Mahoko Takahashi Ueda, So Nakagawa, Gen Komaki, Tetsuya Ando. Rare CRHR2 and GRM8 variants identified as candidate factors associated with eating disorders in Japanese patients by whole exome sequencing. Heliyon. 2024. 10. 8. e28643
Qiaofeng Zhao, Satoshi Koyama, Nagisa Yoshihara, Atsushi Takagi, Etsuko Komiyama, Akino Wada, Akira Oka, Shigaku Ikeda. The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test In cchcr1-Deficient Mice. Biomedicines. 2021. 9. 7. 840-840
Saya Nakakura, Kazuyoshi Hosomichi, Shinya Uchino, Akiko Murakami, Akira Oka, Ituro Inoue, Hirofumi Nakaoka. HLA-B*39:01:01 is a novel risk factor for antithyroid drug-induced agranulocytosis in Japanese population. The Pharmacogenomics Journal. 2021. 21. 1. 94-101
Akira Oka, Atsushi Takagi, Etsuko Komiyama, Nagisa Yoshihara, Shuhei Mano, Kazuyoshi Hosomichi, Shingo Suzuki, Yuko Haida, Nami Motosugi, Tomomi Hatanaka, et al. Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss. EBioMedicine. 2020. 57. 102810-102810
Takashi S. Kajii, Akira Oka, Fumio Saito, Jun Mitsui, Junichiro Iida. Whole-exome sequencing in a Japanese pedigree implicates a rare non-synonymous single-nucleotide variant in BEST3 as a candidate for mandibular prognathism. Bone. 2019. 122. 193-198

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MISC (7)：

鈴木進悟, 伊藤さやか, 重成敦子, 田中正史, 岡晃, 森島聡子, 森島泰雄, 椎名隆. HLAテロメア側ゲノム領域における新規急性GVHD感受性多型の探索. MHC: Major Histocompatibility Complex. 2021. 28. 2Suppl. 103-103
椎名隆, 鈴木進悟, 大貫優子, 岡晃. 【MHCバイオロジー】HLA関連疾患研究の最新情報. 臨床免疫・アレルギー科. 2020. 74. 5. 449-455
岡晃, 鈴木進吾, 大友麻子, 大塚正人, 高木敦, 込山悦子, 吉原渚, 猪子英俊, 池田志斈. マウスにおけるCRISPR/Cas9システムを用いたアレル特異的なゲノム編集による円形脱毛症の症候性スポット状脱毛の表現型の再現(Allele-specific genome editing using the CRISPR/Cas9 system phenocopies alopecia areata symptomatic patched hair loss in mice). MHC: Major Histocompatibility Complex. 2019. 26. 2Suppl. 105-105
IKEDA Shigaku, TAKAGI Atsushi, KOMIYAMA Etsuko, YOSHIHARA Nagisa, MABUCHI Tomotaka, OTOMO Asako, OHTSUKA Masato, OKA Akira. Microsatellite GWAS, risk haplotype sequencing and allele-specific genome editing reveal cchcr1 as a susceptibility gene for alopecia areata. 日本研究皮膚科学会年次学術大会・総会プログラム. 2019. 44th
Tomotaka Mabuchi, Akira Oka, Mariko Iizuka, Yoshinori Umezawa, Takashi Matsuyama, Yumiko Kubota, Juichiro Nakayama, Tadashi Terui, Maki Ozawa, Shinichiro Yasumoto, et al. Fine mapping of a psoriasis-susceptibility locus within the HLA class II region by using microsatellite markers in an association study of Japanese cases and controls. Tokai Journal of Experimental and Clinical Medicine. 2007. 32. 1. 6-13

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