Shimura Tadanobu

シムラタダノブ | Shimura Tadanobu

Affiliation and department：

Research field (1)： Digestive surgery

Research theme for competitive and other funds (4)：

2024 - 2027 Development and validation of a versatile panel targeting colorectal cancer-specific circulating methylated DNA through comprehensive analysis.
2023 - 2026 癌合併クローン病の早期診断を可能とする体液を用いたバイオマーカーの開発
2023 - 2026 The identification and validation of non-invasive DNA methylation biomarker for detection of peritoneal metastasis in gastric cancer patients
2015 - 2017 集学的治療を目的とした、胃癌腹膜播種同定エピゲノムパネルの確立

Papers (82)：

Shinji Yamashita, Yoshinaga Okugawa, Takahito Kitajima, Hideharu Ieki, Mai Shimamura, Ruiya Ma, Koki Higashi, Naru Mizuno, Yuki Sato, Takashi Ichikawa, et al. Association between prognostic immune nutritional index and disease-free survival in adults with esophageal cancer following surgery: A retrospective cohort study. JPEN. Journal of parenteral and enteral nutrition. 2025
Tadanobu Shimura, Chengzeng Yin, Ruiya Ma, Aiying Zhang, Yuka Nagai, Aoi Shiratori, Hana Ozaki, Shinji Yamashita, Koki Higashi, Yuki Sato, et al. The prognostic importance of the negative regulators of ferroptosis, GPX4 and HSPB1, in patients with colorectal cancer. Oncology letters. 2025. 29. 3. 144-144
Yuhki Koike, Koki Higashi, Yuki Sato, Shinji Yamashita, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshinaga Okugawa, Yuji Toiyama. When is the optimal diagnostic biopsy timing of acetylcholinesterase staining in Hirschsprung disease?. BMC pediatrics. 2025. 25. 1. 126-126
Koki Higashi, Yuhki Koike, Yuki Sato, Ma Ruiya, Shinji Yamashita, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, et al. Clinical evaluation of platelet-to-albumin ratio as a predictor of surgical site infection in pediatric patients with ulcerative colitis. Surgery today. 2025
Yuhki Koike, Koki Higashi, Yuki Sato, Shinji Yamashita, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshinaga Okugawa, Yoshiki Okita, et al. Preventive effect of Clostridium butyricum MIYAIRI against pouchitis in children with ulcerative colitis. Surgery today. 2024

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MISC (216)：

今岡裕基, 家城英治, 山下真司, 市川崇, 浦谷亮, 志村匡信, 北嶋貴仁, 川村幹雄, 安田裕美, 奥川喜永, et al. 下部直腸癌に対してTotal Neoadjuvant Therapyと局所切除により臓器温存が得られた1例. 癌と化学療法. 2023. 50. 13. 1866-1868
大北喜基, 川村幹雄, 志村匡信, 今岡裕基, 北嶋貴仁, 小池勇樹, 奥川喜永, 問山裕二. 【進化する炎症性腸疾患の外科治療】Crohn病外科治療総論. 消化器外科. 2023. 46. 11. 1169-1177
井出正造, 問山裕二, 奥川喜永, 楠蔵人, 大村悠介, 山本晃, 北嶋貴仁, 志村匡信, 藤川裕之, 安田裕美, et al. 大腸癌患者におけるPlatelet×C-reactive protein multiplier value(P-CRP)の臨床的意義. 日本外科学会定期学術集会抄録集. 2020. 120回. DP-3
藤川裕之, 問山裕二, 廣純一郎, 大村悠介, 楠蔵人, 山本晃, 市川崇, 井出正造, 志村匡信, 近藤哲, et al. 大腸癌根治手術後における血清Albumin Globulin Ratio(AGR)と予後との関連. 日本外科学会定期学術集会抄録集. 2020. 120回. DP-7
志村匡信, 問山裕二, 奥川喜永, 安田裕美, 藤川裕之, 横江毅, 廣純一郎, 大井正貴, 泉大輔, 馬場秀夫, et al. 胃癌腹膜播種同定に関連するmicroRNA signatureの臨床的意義. 日本外科学会定期学術集会抄録集. 2020. 120回. DP-2

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Professional career (1)：

医学博士

Awards (6)：

2024/11 - Award of excellent presentation Prognostic impact of HSPB1 protein expression in sub-grouped Stage2/3 colorectal cancer patients
2023/06 - Mie University Graduate School of Medicine Award of excellent article published in 2022 in Mie University Graduate School of Medicine
2022/10 - Young Investigator's Award Novel findings for m6A methylation regulators as prognostic biomarkers and FTO as a potential therapeutic target in gastric cancer
2021/07 - EKIDEN for LIFE実行委員会(三重大学内) 生命の駅伝がん研究奨励賞
2020/12 - 三医会・公益財団法人三重医学研究振興会三重医学若手研究者賞進行直腸癌に対する集学的治療の効果を判定し、臓器温存療法を含めたテイラーメイド治療の発展につながるmolecular markerの開発ならびに検証

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