Kayama Hisako

カヤマヒサコ | Kayama Hisako

Affiliation and department：

Research field (1)： Immunology

Research keywords (2)：自然免疫 , 粘膜免疫

Research theme for competitive and other funds (8)：

2021 - 2024 腸管細胞の獲得免疫における動態評価
2021 - 2024 T細胞におけるDAMPs-GPCRs経路活性化を介した腸管炎症制御機構の解明
2019 - 2023 間葉系ストローマ細胞と免疫細胞の相互作用による腸管恒常性維持機構に関する研究開発
2017 - 2021 Evaluation of immune cells and cancer malignancy in colorectal cancer stroma
2017 - 2020 膜型ATP分解酵素E-NTPD8による腸管腫瘍制御機構の解明

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Papers (84)：

Yu Miyamoto, Junichi Kikuta, Takahiro Matsui, Tetsuo Hasegawa, Kentaro Fujii, Daisuke Okuzaki, Yu-chen Liu, Takuya Yoshioka, Shigeto Seno, Daisuke Motooka, et al. Periportal macrophages protect against commensal-driven liver inflammation. Nature. 2024. 629. 8013. 901-909
Li Liu, Takayoshi Ito, Bo Li, Haruka Tani, Daisuke Okuzaki, Daisuke Motooka, Hazuki Miyazaki, Takayuki Ogino, Shota Nakamura, Kiyoshi Takeda, et al. The UDP-glucose/P2Y14 receptor axis promotes eosinophil-dependent large intestinal inflammation. International immunology. 2023
松下慎, 藤田和利, 林拓自, 香山尚子, 元岡大祐, 長谷拓明, 山本顕生, 植村俊彦, 山道岳, 冨山栄輔, et al. 高脂肪食によるディスバイオシスが前立腺癌に及ぼす影響の解明. 泌尿器外科. 2023. 36. 8. 895-896
Thanyakorn Chalalai, Naganori Kamiyama, Benjawan Saechue, Nozomi Sachi, Sotaro Ozaka, Shimpei Ariki, Astri Dewayani, Yasuhiro Soga, Yomei Kagoshima, Supanuch Ekronarongchai, et al. TRAF6 signaling in dendritic cells plays protective role against infectious colitis by limiting C. rodentium infection through the induction of Th1 and Th17 responses. Biochemical and biophysical research communications. 2023. 669. 103-112
Takuro Nii, Yuichi Maeda, Daisuke Motooka, Mariko Naito, Yuki Matsumoto, Takao Ogawa, Eri Oguro-Igashira, Toshihiro Kishikawa, Makoto Yamashita, Satoshi Koizumi, et al. Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis. Annals of the rheumatic diseases. 2023. 82. 5. 621-629

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MISC (19)：

原田武志, 原田昭和, 香山尚子, 佐藤朗, 菊池章. Identification of the fibroblast subsets expressing Wnt5a in AOM/DSS model of colitis-associated colorectal cancer. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
松下慎, 藤田和利, 藤田和利, 林拓自, 香山尚子, 元岡大祐, 長谷拓明, 神宮司健太郎, 山道岳, 弓場覚, et al. 高脂肪食摂取前立腺癌マウスモデルを用いた腸内細菌による代謝産物を介した癌増殖メカニズムの解明. 日本アンドロロジー学会総会記事. 2021. 40th
Yuki Sekido, Junichi Nishimura, Kazuhiro Nakano, Takeaki Osu, Cheryl-Emiliane T Chow, Hiroshi Matsuno, Takayuki Ogino, Shiki Fujino, Norikatsu Miyoshi, Hidekazu Takahashi, et al. Some Gammaproteobacteria are enriched within CD14+ macrophages from intestinal lamina propria of Crohn's disease patients versus mucus. Scientific reports. 2020. 10. 1. 2988-2988
The roles of macrophages in the gut homeostasis. 2016. 259. 5. 441-445
H. Kayama, M. Kohyama, H. Arase, K. Takeda. Dietary iron and transcription factor Spi-C regulate gut homeostasis through maintenance of CX(3)CR1(high) CD11b(+) CD11c(+) cells. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 470-470

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Patents (3)：

腸内細菌数低減剤
炎症性腸疾患を検査する方法
炎症性腸疾患治療用組成物

Education (1)：

2007 - 2009 大阪大学大学院医学系研究科

Work history (1)：

- 現在 Osaka University

Awards (2)：

2020/12 - 第15回日本免疫学会研究研究奨励賞
2020/12 - 令和2年度大阪大学賞若手研究員部門

Association Membership(s) (1)：

THE JAPANESE SOCIETY FOR IMMUNOLOGY

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