Shuichi Aoki

アオキシュウイチ | Shuichi Aoki

Affiliation and department：

Research field (3)： Digestive surgery , Molecular biology , Tumor biology

Research keywords (11)： cancer stroma , cancer associated fibroblast , adjuvant therapy , neoadjuvant therapy , surgery , immunotherapy , Gallbladder cancer , bile duct cancer , hepatocellular carcinoma , cholangiocaricinoma , pancreatic cancer

Research theme for competitive and other funds (7)：

2022 - 2025 膵癌術前治療耐性克服を目指したcollagen XVIIを標的とする新規治療開発
2021 - 2024 Bile cell-free DNAを用いゲノム多様性を標的にした胆道癌新規治療
2021 - 2024 胆管癌における休眠がん細胞のメカニズムの解明
2021 - 2024 A novel therapeutic strategy for pancreatic and biliary tract cancer by targeting the intestinal microbiota for anti-tumor immune activation
2020 - 2023 細胞外マトリックス阻害による腫瘍免疫活性化を目指した新規膵癌治療戦略

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Papers (116)：

Masahiro Iseki, Masamichi Mizuma, Mitsuhiro Shimura, Takashi Kokumai, Hideaki Sato, Akiko Kusaka, Shuichi Aoki, Koetsu Inoue, Shun Nakayama, Daisuke Douchi, et al. Preoperative chemotherapy with Gemcitabine for pancreatic cancer causes zinc deficiency. Pancreas. 2024
Yuko Omori, Shuichi Aoki, Yusuke Ono, Takashi Kokumai, Shingo Yoshimachi, Hideaki Sato, Akiko Kusaka, Masahiro Iseki, Daisuke Douchi, Takayuki Miura, et al. Clonal analysis of metachronous double biliary tract cancers. The Journal of pathology. 2024. 263. 1. 113-127
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Zelong Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, et al. Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy. Cancer immunology research. 2024. 12. 4. 400-412
Yushi Inomata, Takeo Naito, Takashi Hiratsuka, Yusuke Shimoyama, Rintaro Moroi, Hisashi Shiga, Yoichi Kakuta, Kimiko Kayada, Yuki Ohara, Naoki Asano, et al. Rupture of ectopic varices of the ascending colon occurring after pancreatic cancer surgery: A case report and literature review. DEN open. 2024. 4. 1. e255
水間正道, 國米崇, 柏木良介, 日下彬子, 青木修一, 伊関雅裕, 井上亨悦, 堂地大輔, 中山瞬, 三浦孝之, et al. 膵退形成癌に対する術前治療. 日本消化器外科学会雑誌. 2023. 56. Suppl.2. 379-379

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MISC (177)：

海野裕一郎, 青木修一, 村上圭吾, 安藤未佳, 柏木良介, 井上亨悦, 伊関雅裕, 三浦孝之, 石田晶玄, 大塚英郎, et al. 肝内胆管癌におけるHGF/METシグナルの亢進は免疫抑制的な微小環境を創出する. 日本外科学会定期学術集会抄録集. 2023. 123回. DP-7
水間正道, 國米崇, 柏木良介, 日下彬子, 青木修一, 伊関雅裕, 井上亨悦, 堂地大輔, 中山瞬, 三浦孝之, et al. 膵退形成癌に対する術前治療. 日本消化器外科学会雑誌(Web). 2023. 56. Supplement2
堂地大輔, 國米崇, 佐藤英昭, 日下彬子, 青木修一, 伊関雅裕, 三浦孝之, 前田晋平, 石田晶玄, 大塚英郎, et al. Response Evaluation of the Neoadjuvant Therapy for Pancreatic Cancer. 胆と膵. 2023. 44. 8
森川孝則, 石田晶玄, 伊関雅裕, 宮崎健人, 日下彬子, 井上亨悦, 青木修一, 中山瞬, 堂地大輔, 三浦孝之, et al. 外科系周術期栄養のアップデート膵臓外科における周術期栄養評価の重要性. New Diet Therapy. 2022. 38. 2. 100-100
平野直大, 伊関雅裕, 水間正道, 野口彩, 青木修一, 井上亨悦, 中山瞬, 三浦孝之, 石田晶玄, 大塚英郎, et al. 切除可能境界膵体部癌に対して術前治療により病理学的完全奏効が得られた1例. 日本消化器病学会東北支部例会プログラム・抄録集. 2022. 213回. 71-71

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Lectures and oral presentations (6)：

Blockade of PlGF inhibits ICC progression by targeting tumor-stroma interactions
(Annual Conference of Cholangiocarcinoma Foundation 2019)
Aberrant activation of placental growth factor/Neuropilin 1 pathway in intrahepatic cholangiocarcinoma: Therapeutic potential
(IASGO World Congress 2017)
Serum Carbohydrate Antigen 19-9 Values after Neoadjuvant Therapy Predict Survival of Patients with Pancreatic Adenocarcinoma: A Multicenter Case-Control Study of 269 Patients
(DDW 2015)
Clinicopathological features of distal cholangiocarcinoma: comparison between extra- and intrapancreatic bile duct
(Asian-Pacific Hepato-Pancreato-Biliary Association 2015)
The surgical anatomy of hilar hepatic artery in left-sided hepatectomy and caudate lobectomy for hilar cholangiocarcinoma
(International Surgical Week 2013)

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Professional career (2)：

M.D. (Tohoku University School of Medicine)
Ph.D. (Tohoku University Graduate School of Medicine)

Work history (5)：

2019/04 - 現在 Tohoku University Graduate School of Medicine Department of Surgery
2016/04 - 2019/03 Massachusetts General Hospital, Harvard Medical School Edwin L. Steele Laboratory for Tumor Biology Research Fellow
2012/04 - 2016/03 Tohoku University Graduate School of Medicine Department of Surgery
2010/04 - 2012/03 Shizuoka Cancer Center Division of Hepato-biliary-Pancreatic Surgery Chief resident
2006/04 - 2010/03 Hiraka General Hospital General Surgeon

Awards (4)：

2019 - Annual Conference of Cholangiocarcinoma Foundation A invited talk
2019 - Asian-Pacific Hepato-Pancreato-Biliary Association A travel grant
2019 - NIH-Japan-JSPS joint symposium A travel grant
2015 - DDW A poster award

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