Rchr
J-GLOBAL ID：201901017634970261
Update date: May. 15, 2024
Lim Kee Siang
Lim Kee Siang
Affiliation and department：
Job title：
Specially Appointed Assistant Professor
Research field (6)：
Molecular biology
, Virology
, Biochemistry
, Nanobioscience
, Tumor biology
, Cell biology
Research keywords (6)：
Viral proteins
, Nanoimaging
, Cancer Biology
, Oncoimmunology
, High Speed Atomic Force Microscopy
, Nuclear Pore Complex
Research theme for competitive and other funds (2)：
- 2020 - 2024 Real-time observation of native conformations and molecular behaviors of viral fusion proteins using high-speed atomic force microscopy (HS-AFM)
- 2019 - 2020 Direct visualization of avian influenza H5N1 Hemagglutinin precursor and its conformational change by high-speed atomic force microscopy
Papers (28)：
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Keesiang Lim, Masaharu Hazawa, Richard W. Wong. Crafty mimicry grants nuclear pore entry to HIV. Cell Host & Microbe. 2024. 32. 4. 441-442
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Yujia Qiu, Elma Sakinatus Sajidah, Sota Kondo, Shinnosuke Narimatsu, Muhammad Isman Sandira, Yoshiki Higashiguchi, Goro Nishide, Azuma Taoka, Masaharu Hazawa, Yuka Inaba, et al. An Efficient Method for Isolating and Purifying Nuclei from Mice Brain for Single-Molecule Imaging Using High-Speed Atomic Force Microscopy. Cells. 2024. 13. 3. 279-279
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Masaharu Hazawa, Dini Kurnia Ikliptikawati, Yuki Iwashima, De-Chen Lin, Yuan Jiang, Yujia Qiu, Kei Makiyama, Koki Matsumoto, Akiko Kobayashi, Goro Nishide, et al. Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells. Cell Chemical Biology. 2023
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Zuzana Dunajova, Batirtze Prats Mateu, Philipp Radler, Keesiang Lim, Dörte Brandis, Philipp Velicky, Johann Georg Danzl, Richard W. Wong, Jens Elgeti, Edouard Hannezo, et al. Chiral and nematic phases of flexible active filaments. Nature Physics. 2023
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Goro Nishide, Keesiang Lim, Maiki Tamura, Akiko Kobayashi, Qingci Zhao, Masaharu Hazawa, Toshio Ando, Noritaka Nishida, Richard W. Wong. Nanoscopic Elucidation of Spontaneous Self-Assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Open Reading Frame 6 (ORF6) Protein. The Journal of Physical Chemistry Letters. 2023. 8385-8396
ｍore...
MISC (2)：
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LIM Keesiang, 西出梧朗, 中山隆宏, 華山力成, 華山力成, 安藤敏夫, WONG Richard W., WONG Richard W. SARS-CoV-2スパイクタンパク質の構造ダイナミクスとACE2受容体および小さな細胞外小胞との相互作用のミリ秒追跡。. 日本生化学会大会(Web). 2022. 95th
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Kee Siang Lim, Ley Fang Kua, Kosaku Mimura, Kensuke Shiraishi, Wee Joo Chng, Wei Peng Yong, Dario Campana, Koji Kono. Implication of highly cytotoxic natural killer cells for esophageal cancer treatment. CANCER RESEARCH. 2015. 75
Lectures and oral presentations (15)：
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Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM
(The 7th WPI NanoLSI Symposium 2023)
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Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.
(The 70th Annual Meeting of the Japanese Society for Virology 2023)
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Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM
(The 3rd Meeting of Cross-Scale Biology Conference 2023)
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Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.
(The 23rd annual meeting of the Protein Science Society of Japan 2023)
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Structural dynamics of SARS-CoV-2 spike (S) protein and its interaction with ACE2 receptor and small extracellular vesicles
(Cross-Scale Biology 1st Wakate meeting 2022)
ｍore...
Education (2)：
- 2012 - 2017 National University of Singapore (NUS) Cancer Science Institute Cancer Biology
- 2005 - 2009 National University of Malaysia (UKM) Biomedical Science with Honours
Work history (2)：
- 2017/05 - 2018/05 National University of Singapore Cancer Science Institute (CSI) Postdoctoral Researcher
- 2010/01 - 2012/06 National University of Singapore Department of Surgery Research Assistant
Awards (2)：
- 2021/07 - Kanazawa University Papers of the Month Visualization of physical interaction between histone and DNA using high-speed AFM
- 2020/11 - Kanazawa University Papers of the Month Mechanism of actions of influenza A virus HA in fusion between viral and host membranes revealed by high-speed AFM
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