Oku Yoshitaka

Affiliation and department：
Job title： Special Invited Professor

Research field (1)： Physiology

Research theme for competitive and other funds (21)：

2021 - 2024 神経干渉波刺激装置を用いた食道癌術後不顕性誤嚥予防のための新規リハビリの開発
2021 - 2024 嚥下超音波検査法と深層学習を融合した誤嚥検出アルゴリズムの開発
2020 - 2023 Mechanisms of rhythm fluctuation in the respiratory center
2017 - 2020 Coordination between breathing and swallowing as a predictor of COPD exacerbation
2016 - 2019 Biosignal Analysis for Screening Dysphagia in daytime and nighttime based on Pattern recognition

2015 - 2018 Effects of respiratory control on task performance

2015 - 2018 Mathematical Understanding of lnformation Processing Mechanism in the Brain by lnteraction of Glial and Neuronal Networks

2014 - 2018 Elucidation of functional connectivity between neurons and astrocytes that generate self-excited synchronization phenomenon in the respiratory center

2013 - 2015 Effects of interferential current stimulation on swallowing reflex in dysphagic patients

2012 - 2015 Elucidation of the Brain Operating Principles by Analyzing Large Scale Neuron-Astrocyte Networks with Genetic Algorithm

2012 - 2015 Physiological and mathematical modeling of periodic synchronized neural firing phenomenon by data driven approach

2011 - 2013 The elucidation of central chemosensitive respiratory regulation by TRP channels expressed in glial cell.

2011 - 2012 Astrocytes drive respiratory rhythm testing a new paradigm

2010 - 2012 Role of chitinase like protein in chronic inflammatory airway diseases

2008 - 2010 Analysis of the neuronal network that generates respiratory rhythm and pattern

2008 - 2010 Developmental changes in central respiratory rhythmogenesis

2007 - 2010 Study of Rhythm Formation Mechanism in Brainstem by Statistical Analysis of Spatio-Temporal Voltage Imaging Data

2007 - 2009 Coordination and dissociation of nonlinear oscillations in cardiomyocytes : dysfunction of holonic oscillators leading to arrhythmias

1999 - 2000 人工ニューロンネットワークを用いた機能的電気刺激による呼吸と咳の再生と協調

1996 - 1997 Acute response of lung mechanics to hypoxia and histamine

1994 - 1994 睡眠・覚醒に伴う呼吸ニューロン活動変化に起こるセロトニンニューロンの役割

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Papers (127)：

Kazuhito Nomura, Eichi Narimatsu, Yoshihiko Oke, Yoshitaka Oku. The lesion site of organophosphorus-induced central apnea and the effects of antidotes. Scientific Reports. 2023. 13. 1
Nozomu H. Nakamura, Yoshitaka Oku, Masaki Fukunaga. “Brain-breath” interactions: respiration-timing-dependent impact on functional brain networks and beyond. Reviews in the Neurosciences. 2023. 35. 2. 165-182
Ryo Kawabata, Hiroki Yamanaka, Kimiko Kobayashi, Yoshihiko Oke, Ayumi Fujita, Yoshitaka Oku, Ikuko Yao, Kohei Koga. The Anterior Cingulate Cortex is Critical for Acute Stress-induced Hypersensitivity in Mice. Neuroscience. 2023. 523. 47-60
Yoshihiko Oke, Fumikazu Miwakeichi, Yoshitaka Oku, Johannes Hirrlinger, Swen Hülsmann. Cell types and synchronous-activity patterns of inspiratory neurons in the preBötzinger complex of mouse medullary slices during early postnatal development. Scientific reports. 2023. 13. 1. 586-586
Yoshitaka Oku, Naomi Yagi, Madoka Nishino, Tadasuke Shinkawa, Yu Takata, Shinsuke Nagami, Masahiro Okada. Swallowing Dynamics and Breathing-Swallowing Coordination Are Altered in Patients with Mild Cognitive Impairment. Dementia and geriatric cognitive disorders. 2021. 50. 6. 554-558

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MISC (24)：

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