Rchr
J-GLOBAL ID：201901018576224461
Update date: Apr. 02, 2024
Keigo Araki
アラキ ケイゴ | Keigo Araki
Affiliation and department：
Other affiliations (1)：
Research field (1)：
Molecular biology
Research theme for competitive and other funds (3)：
- 2022 - 2025 「匂いシグナル」で制御される口腔がん細胞の細胞融合誘導機構の解析
- 2017 - 2021 Development of new therapies for malignant cancers through disruption of quality control machinery of mitochondria
- 2015 - 2017 Inhibition of G-quadruplex formation of E2F3 mRNA enhances its expression in cancer cells
Papers (20)：
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Yaxuan Zhou, Rinka Nakajima, Mashiro Shirasawa, Mariana Fikriyanti, Lin Zhao, Ritsuko Iwanaga, Andrew P Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani. Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression. Biology. 2023. 12. 12
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Rinka Nakajima, Reika Deguchi, Hideyuki Komori, Lin Zhao, Yaxuan Zhou, Mashiro Shirasawa, Arlene Angelina, Yasuko Goto, Fumiya Tohjo, Kengo Nakahashi, et al. The TFDP1 gene coding for DP1, the heterodimeric partner of the transcription factor E2F, is a target of deregulated E2F. Biochemical and Biophysical Research Communications. 2023. 663. 154-162
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Nakajima R, Zhao L, Zhou Y, Shirasawa M, Uchida A, Murakawa H, Fikriyanti M, Iwanaga R, Bradford AP, Araki K, et al. Deregulated E2F Activity as a Cancer-Cell Specific Therapeutic Tool. Genes (Basel). 2023. 14. 2. 393
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T Miyazaki, Z Zhao, Y Ichihara, D Yoshino, T Imamura, K Sawada, S Hayano, H Kamioka, S Mori, H Hirata, et al. Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity. Science advances. 2019. 5. 9. eaau7802
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Keigo Araki, Keiko Kawauchi, Wataru Sugimoto, Daisuke Tsuda, Hiroya Oda, Ryosuke Yoshida, Kiyoshi Ohtani. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Communications biology. 2019. 2. 3-3
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MISC (4)：
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Keigo Araki, Kiyoshi Ohtani. E2F3d, a novel E2F family member, contributes to mitochondrial quality control in cancer. Journal of Japanese Biochemical Society. 2019. 91. 6. 781-784
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荒木 啓吾, 服部 拓, 行本 愛, 川内 敬子, 大谷 清. アデノウィルスE1aによる転写因子E2F3の新たな発現調節機構. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [2P1084]-[2P1084]
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川内 敬子, 荒木 啓吾, 飛梅 圭, 田中 信之. p53欠損細胞のトランスフォームにおけるNF-kappaBの役割(Role of NF-kappaB for cell transformation in p53 deficient cells). 日本癌学会総会記事. 2007. 66回. 266-266
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Keigo Araki. 癌の発生と細胞周期の制御. 2003. 70. 3. 195-195
Books (2)：
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Distinct E2F-Mediated Transcriptional Mechanisms in Cell Proliferation, Endoreplication and Apoptosis
InTech Open Access Publisher 2018
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The Key Role of E2F in Tumor Suppression through Specific Regulation of Tumor Suppressor Genes in Response to Oncogenic Changes
InTech Open Access Publisher 2018
Lectures and oral presentations (1)：
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Analysis of cell-cell fusion mechanism in cervical cancers
(2023)
Education (2)：
- 1999 - 2003 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
- 1993 - 1999 Tokyo Medical and Dental University Faculty of Dentistry School of Dentistry
Professional career (1)：
Work history (5)：
- 2020/04 - 現在 Ohu University Faculty of Dentistry
- 2015/04 - 2019/03 Kwansei Gakuin University School of Science and Technology Department of Biomedical Chemistry
- 2013/07 - 2014/03 シンガポール大学 メカノバイオロジー研究所
- 2008/08 - 2013/06 シンガポール大学 がん研究所
- 2005/04 - 2007/09 Nippon Medical School
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