Uehara Ryo

ウエハラリョウ | Uehara Ryo

Affiliation and department：

Research field (1)： Cell biology

Research keywords (4)： Genome integrity , RNA , Molecular Biology , Protein Engineering

Research theme for competitive and other funds (5)：

Papers (14)：

Fumie Mitani, Jianyu Lin, Tatsuya Sakamoto, Ryo Uehara, Tomoya Hikita, Takuya Yoshida, Andi Setiawan, Masayoshi Arai, Chitose Oneyama. Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function. Scientific Reports. 2022. 12. 1. 6674
Tomoya Hikita, Ryo Uehara, Reina E. Itoh, Fumie Mitani, Mamiko Miyata, Takuya Yoshida, Rui Yamaguchi, Chitose Oneyama. MEK/ERK-mediated oncogenic signals promote secretion of extracellular vesicles by controlling lysosome function. Cancer Science. 2022. 113. 4. 1264-1276
Ryo Uehara, Nanako Dan, Hiroshi Amesaka, Takuya Yoshizawa, Yuichi Koga, Shigenori Kanaya, Kazufumi Takano, Hiroyoshi Matsumura, Shun-ichi Tanaka. Insertion loop-mediated folding propagation governs efficient maturation of hyperthermophilic Tk-subtilisin at high temperatures. FEBS Letters. 2021. 595. 4. 452-461
Ryo Uehara, Riki Iwamoto, Sayaka Aoki, Takuya Yoshizawa, Kazufumi Takano, Hiroyoshi Matsumura, Shun-ichi Tanaka. Crystal structure of a GH1 β-glucosidase from Hamamotoa singularis. Protein Science. 2020. 29. 9. 2000-2008
Misato Baba, Kenji Kojima, Takuto Nishimura, Takuya Sugiura, Teisuke Takita, Ryo Uehara, Robert J. Crouch, Kiyoshi Yasukawa. Val143 of human ribonuclease H2 is not critical for, but plays a role in determining catalytic activity and substrate specificity. PLOS ONE. 2020. 15. 2. e0228774-e0228774

ｍore...

MISC (5)：

上原了, 田中俊一. 超好熱性サチライシンをモデルにみるタンパク質フォールディングの高温環境適応戦略. 化学と生物. 2021. 59. 6. 272-274
上原了. 染色体DNAにおけるリボヌクレオチドの許容限界. 生化学. 2020. 92. 5. 744-747
Uehara Ryo, Takeuchi Yuki, Tanaka Shun-ichi, Takano Kazufumi, Koga Yuichi, Kanaya Shigenori. 3Hp02 Ca^<2+>-dependent stabilization mechanism of Tk-subtilisin from hyperthermophile. 2012. 64. 151-151
Uehara Rryo, Ueda Yasunori, Koga Yuichi, Takano Kazufumi, Kanaya Shigenori. 1Ep19 The mechanism for accelerating maturation of Tk-subtilisin. 2011. 63. 43-43
UEHARA Ryo, TANAKA Shunichi, KOGA Yuichi, TAKANO Kazufumi, KANAYA Shigenori. 2P-1100 Tk-subtilisin stabilization mechanism during maturation. 2010. 22. 33-33

Books (2)：

Biotechnology of Microbial Enzymes: Production, Biocatalysis and Industrial applications
Academic Press 2016
Serine Proteases: Mechanism, Structure and Evolution
Nova Science Publishers, Inc. 2012

Education (2)：

2008 - 2013 Osaka University Graduate School of Engineering Department of Material and Life Science
2004 - 2008 Osaka University School of Engineering Division of Applied Science

Professional career (1)：

Work history (6)：

2023/04 - 現在立命館大学生命科学部生物工学科助教
2020/04 - 2023/03 Aichi Cancer Center, Research Institute
2019/04 - 2020/03 Ritsumeikan University Ritsumeikan Global Innovation Research Organization Assistant Professor
2019/02 - 2019/03 Ritsumeikan University Ritsumeikan Global Innovation Research Organization Senior Researcher
2013/10 - 2019/01 National Institutes of Health Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development Visiting Fellow

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Awards (1)：

Association Membership(s) (3)：

日本生化学会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , PROTEIN SCIENCE SOCIETY OF JAPAN

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