Research keywords (4)：
Skeletal Development
, Chronic Recurrent Multifocal Osteomyelitis
, Autoinflammation
, Mouse Genetics
Research theme for competitive and other funds (7)：
2021 - 2024 Molecular dissection of bone pain using a mouse model for autoinflammatory disease
2018 - 2022 Production of humanized mouse models for chronic recurrent multifocal osteomyelitis and antiinflammatory drug development
2018 - 2021 Elucidation of the effects of assisted reproductive technology and maternal environmental factors on higher brain function and construction of its risk assessment system
2013 - 2016 Molecular analysis of mast cell activation in mouse models for autoinflammatory syndromes and its use for anti-inflammatory drug development
2010 - 2012 Analysis of the inflammatory mechanisms caused by the Ali18 mutation in molecular and cellular levels
2007 - 2009 Identification and characterization of the Ali18 mutation, which causes inflammatory arthritis in mice
1996 - 1997 Analysis of functions and differentiation of mast cells
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Papers (28)：
Ryo Yoshikawa, Koichiro Abe. The multi-kinase inhibitor dasatinib suppresses autoinflammation and increases bone density in a mouse model for chronic recurrent multifocal osteomyelitis. Cell Biochemistry and Function. 2021. 39. 4. 521-527
Helmut Fuchs, Sibylle Sabrautzki, Gerhard K H Przemeck, Stefanie Leuchtenberger, Bettina Lorenz-Depiereux, Lore Becker, Birgit Rathkolb, Marion Horsch, Lillian Garrett, Manuela A Östereicher, et al. The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations. G3 (Bethesda, Md.). 2016. 6. 12. 4035-4046
Shinji Hadano, Shun Mitsui, Lei Pan, Asako Otomo, Mizuki Kubo, Kai Sato, Suzuka Ono, Wakana Onodera, Koichiro Abe, XuePing Chen, et al. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice. Human molecular genetics. 2016. 25. 15. 3321-3340
