Yoshimura Aya

ヨシムラアヤ | Yoshimura Aya

Affiliation and department：

Research field (2)： Environmental and pharmaceutical development resources , Bioorganic chemistry

Research keywords (5)： genome mining , membrane vesicle , cryptic biosynthetic gene cluster , Chemical Biology , Natural Product Chemistry

Research theme for competitive and other funds (6)：

2023 - 2026 多様な細胞外膜小胞の天然物生産誘導メカニズム解明による天然物探索基盤の構築
2022 - 2025 Studies on bacterial cell-to-cell communication through membrane vesicles and secondary metabolites
2020 - 2023 休眠遺伝子覚醒機構の解明と新規天然物探索基盤の確立
A rational approach to obtaining bacterial secondary metabolites by pseudo-interbacterial communication
微生物の休眠遺伝子由来天然物の開拓による抗菌性化合物ライブラリーの拡張

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Papers (11)：

Jabal Rahmat Haedar, Aya Yoshimura, Toshiyuki Wakimoto. New variochelins from soil-isolated Variovorax sp. H002. Beilstein Journal of Organic Chemistry. 2024
Aya Yoshimura, Takumi Honda, Toshiyuki Wakimoto. Five New Analogs of Streptogramin Antibiotic Viridogrisein Isolated from Streptomyces niveoruber. Chemical and Pharmaceutical Bulletin. 2024. 72. 1. 80-85
Aya Yoshimura, Rio Saeki, Ryusuke Nakada, Shota Tomimoto, Takahiro Jomori, Keisuke Suganuma, Toshiyuki Wakimoto. Membrane-Vesicle-Mediated Interbacterial Communication Activates Silent Secondary Metabolite Production. Angewandte Chemie International Edition. 2023
Kohei Fujita, Misa Ikuta, Shinichi Nishimura, Ryosuke Sugiyama, Aya Yoshimura, Hideaki Kakeya. Amphiol, an Antifungal Fungal Pigment from Pseudogymnoascus sp. PF1464. Journal of Natural Products. 2021. 84. 4. 986-992
Aya Yoshimura, Brett C. Covington, Étienne Gallant, Chen Zhang, Anran Li, Mohammad Seyedsayamdost. Unlocking Cryptic Metabolites with Mass Spectrometry-Guided Transposon Mutant Selection. ACS Chemical Biology. 2020. 15. 10. 2766-2774

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MISC (3)：

Aya Yoshimura, Dainan Mao, Rurun Wang, Mohammad Seyedsayamdost. Using Transposon Mutagenesis to Activate Cryptic Biosynthetic Gene Clusters in Burkholderia spp. 2019
吉村彩, 西村慎一, 岸本真治, 服部明, 掛谷秀昭. 1,3-Dimethyl鎖状構造の立体配置決定法の検証:tumescenamide Cとverucopeptinを例に. 日本薬学会年会要旨集(CD-ROM). 2013. 133rd
吉村彩, 大塚紗織, 西村慎一, 服部明, 長田裕之, 掛谷秀昭. 低酸素誘導因子(HIF)活性化経路を阻害するverucopeptinの化学的解析研究. 天然有機化合物討論会講演要旨集(Web). 2012. 54th

Education (1)：

Professional career (1)：

Work history (3)：

2019/09 - 現在 Hokkaido University Graduate School of Pharmaceutical Sciences Assistant Professor
2017/09 - 2019/08 Princeton University Department of Chemistry Postdoctral Fellow
2017/04 - 2017/08 Osaka University Graduate School of Pharmaceutical Sciences Postdoctral Fellow

Awards (2)：

2023/11 - Japan Symposium of Microbial Ecology & Asian Symposium of Microbial Ecology Excellent Poster Award
2022/06 - 日本薬学会生薬天然物部会生薬天然物部会奨励研究賞

Association Membership(s) (4)：

日本微生物生態学会 , 日本農芸化学会 , 日本生薬学会 , 日本薬学会

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