Mizukami Shusaku

ミズカミシュウサク | Mizukami Shusaku

Affiliation and department：
Homepage URL (1)： http://www.tm.nagasaki-u.ac.jp/nekken/

Research field (1)： Immunology

Research theme for competitive and other funds (7)：

2021 - 2024 Development of innovative T cell-inducing vaccine drug based on mRNA delivery
2021 - 2024 Single cell analysis of TCR genotypes of CTL at recovery phase of acute Dengue infection
2020 - 2023 細胞内タンパク質分解に着目したデングウイルスワクチン開発のための基盤的研究
2017 - 2020 Antigenic variation can change T cell immunity in malaria?
2016 - 2019 Analysis of cellular immunity on dengue infected HLA transgenic mouse

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Papers (44)：

Awet Alem Teklemichael, Aiko Teshima, Asahi Hirata, Momoko Akimoto, Mayumi Taniguchi, Gholam Khodakaramian, Takashi Fujimura, Fuyuki Tokumasu, Kenji Arakawa, Shusaku Mizukami. Discovery of antimalarial drugs from secondary metabolites in actinomycetes culture library. Tropical Medicine and Health. 2024
Yuki Tayama, Shusaku Mizukami, Kazufumi Toume, Katsuko Komatsu, Tetsuo Yanagi, Takeshi Nara, Paul Tieu, Nguyen Tien Huy, Shinjiro Hamano, Kenji Hirayama. Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents. Tropical medicine and health. 2023. 51. 1. 12-12
Satoshi Mizuta, Farhana Mosaddeque, Mya Myat Ngwe Tun, Awet Alem Teklemichael, Mayumi Taniguchi, Masashi Hosokawa, Tomoko Yamaguchi, Juliann Makau, Nguyen Tien Huy, Shusaku Mizukami, et al. Challenges Based on Antiplasmodial and Antiviral Activities of 7-Chloro-4-aminoquinoline Derivatives. ChemMedChem. 2023
Sayuri Nakamae, Satoshi Miyagawa, Koki Ogawa, Mariko Kamiya, Mayumi Taniguchi, Akari Ono, Maho Kawaguchi, Awet Alem Teklemichael, Jiun-Yu Jian, Tamasa Araki, et al. Induction of liver-resident memory T cells and protection at liver-stage malaria by mRNA-containing lipid nanoparticles. Frontiers in immunology. 2023. 14. 1116299-1116299
Maho Kawaguchi, Marin Noda, Akari Ono, Mariko Kamiya, Makoto Matsumoto, Masako Tsurumaru, Shusaku Mizukami, Hidefumi Mukai, Shigeru Kawakami. Effect of Cholesterol Content of Lipid Composition in mRNA-LNPs on the Protein Expression in the Injected Site and Liver After Local Administration in Mice. Journal of pharmaceutical sciences. 2022

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MISC (12)：

Linh Tran, Dao Ngoc Hien Tam, Abdullah Reda, Atia Hasan Tahoon, Jeza M.Abdul Aziz, Phan Thi My Tien, Nguyen Hai Nam, Karim Mohamed Shahin, Jaffer Shah, Shusaku Mizukami, et al. A systematic review of antimalarial activities of Morinda species. South African Journal of Botany. 2022. 148. 396-406
水田賢志, FARHANA Mosaddeque, NGUYEN Tien Huy, 水上修作, 平山謙二. Drug Discovery Opportunities based on Anti-Plasmodium falciparum and anti-influenza virus A activities of quinoline derivatives. 日本薬学会年会要旨集(Web). 2022. 142nd
A. Mohammed, D. N.H. Tam, T. L.H. Vu, T. M. Tieu, M. K. Elfaituri, N. N. Trinh, E. A. Sagheir, Linh Tran, T. T.H. Loc, S. K. Low, et al. Morinda morindoides: A systematic review of its therapeutic activities. South African Journal of Botany. 2020. 131. 93-103
成瀬妙子, TEKLEMICHAEL Awet M, GITONGA Peterson M, 楢原千里, 水上修作, BENEDICTE Moni M, AVENIDO Eleonor F, MERCADO Edelwisa S, ESPINO Espelanza F, JIZ Mario, et al. Polymorphisms of the GPI8p gene of P. falciparum in Palawan Island, Philippines. 日本寄生虫学会大会プログラム・抄録集. 2020. 89th
榮川伸吾, 西田充香子, 水上修作, 山崎千尋, 國定勇希, 上原健敬, 有吉勇一, 鵜殿平一郎. 腫瘍局所における免疫疲弊CD8T細胞の機能回復を介したメトホルミンの抗腫瘍効果. 日本がん免疫学会総会プログラム・抄録集. 2013. 17th

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Lectures and oral presentations (15)：

mRNA封入脂質ナノ粒子を用いたマラリアワクチン開発研究
(2023年度遺伝子・デリバリー研究会夏期セミナー 2023)
細胞性免疫に着目した肝細胞期マラリアワクチン開発研究
(第79回HiHA Seminar 2023)
熱帯医学領域における免疫学的解析・創薬研究
(第56回 HiHA Webセミナー (Webinar) 2020)
Antigen specificity and T cell receptor profiling of dengue virus primed T cells using iPS cell derived dendritic cells.
(Asian-African Research Forum on Emerging and Reemerging Infection 2019 2019)
身近になった熱帯病〜デング熱と生体防御〜
(高校教職員のためのWinterSchool 2018@ 微研感染症とたたかう免疫のしくみ 2018)

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Education (2)：

- 2008 Nagasaki University Graduate School of Biomedical Sciences
- 2002 Nagasaki University School of Medicine

Professional career (1)：

博士(医学) (長崎大学)

Work history (7)：

2024/04 - 現在 Nagasaki University
2019/04 - 現在 Nagasaki University Institute of Tropical Medicine
2018/04 - 2019/03 Nagasaki University Research Field of Pathogenesis and Clinical Sciences, Institute of Tropical Medicine
2015/09 - 2018/03 Nagasaki University Institute of Tropical Medicine
2014/03 - 2015/08 Nagasaki University Research Field of Pathogenesis and Clinical Sciences, Institute of Tropical Medicine

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Committee career (5)：

2021/04 - 現在日本寄生虫学会評議員
2021/04 - 2023/03 長崎大学組換えDNA実験安全委員会委員長
2016/04 - 2023/03 長崎大学組換えDNA実験安全委員会委員
2019/04 - 2021/03 長崎大学組換えDNA実験安全委員会副委員長
2016/04 - 2020/03 長崎大学放射線同位元素等安全管理委員会委員

Awards (1)：

2010/07 - 日本がん免疫学会若手研究奨励賞

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