Kubota Hiroshi

クボタヒロシ | Kubota Hiroshi

Affiliation and department：

Research field (1)： Zoological sciences

Research keywords (2)：生殖系列 , 幹細胞

Research theme for competitive and other funds (9)：

2021 - 2024 機能的スクリーニングによる種特異的精子形成誘導因子の同定
2020 - 2023 トランスジェニックヌードマウスを利用した精原幹細胞異種移植法の開発
2013 - 2015 Generation of induced spermatogonial stem cells by direct reprogramming
2011 - 2014 Identification of regulatory molecules governing self-renewal versus differentiation of spermatogonial stem cells
2008 - 2010 Unraveling the molecular mechanisms of spermatogenesis using differentiation-deficient spermatogonial stem cells

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Papers (35)：

Huijuan Lin, Keren Cheng, Hiroshi Kubota, Yemin Lan, Simone S Riedel, Kazue Kakiuchi, Kotaro Sasaki, Kathrin M Bernt, Marisa S Bartolomei, Mengcheng Luo, et al. Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells. Genes & development. 2022. 36. 11-12. 752-763
Hiroshi Kubota, Kazue Kakiuchi. Long-Term Ex Vivo Expansion of Murine Spermatogonial Stem Cells in a Simple Serum-Free Medium. Methods in Molecular Biology; Stem Cells and Tissue Repair. 2020. 2155. 165-182
Kamijo A, Saitoh Y, Sakamoto T, Kubota H, Yamauchi J, Terada N. Scaffold protein Lin7 family in membrane skeletal protein complex in mouse seminiferous tubules. Histochemistry and cell biology. 2019. 152. 5. 333-343
Hiroshi Kubota. Heterogeneity of Spermatogonial Stem Cells. Advances in experimental medicine and biology; Stem Cells Heterogeneity in Different Organs. 2019. 1169. 225-242
Kazue Kakiuchi, Kazumi Taniguchi, Hiroshi Kubota. Conserved and non-conserved characteristics of porcine glial cell line-derived neurotrophic factor expressed in the testis. Scientific Reports. 2018. 8. 1. 7656

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MISC (14)：

Kubota H, Brinster RL. Germ cell transplantation. Encyclopedia of Reproduction, Second Edition. 2018. 1. 171-179
Kubota H, Brinster RL. Spermatogonial transplantation and spermatogonial stem cell competence. Encyclopedia of Reproduction, Second Edition. 2018. 3. 105-113
KUBOTA Hiroshi. 配偶子形成. 2011. 75-83
KUBOTA Hiroshi. Self-renewal and differentiation of spermatogonial stem cells derived from congenitally infertile mice. 2010. 27. 2. S5
久保田浩司. Searching for stem cell properties of mate germline-derived stem cells. Cell technology. 2007. 26. 5. 517-522

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Lectures and oral presentations (10)：

Conserved and non-conserved characteristics of spermatogonial stem cells in mammals
(Stem Cells, Germ Cells, and Epigenetics for Primate Research 2014)
精原幹細胞:基礎から応用まで非齧歯類哺乳動物の精原幹細胞培養系
(The Journal of Reproduction and Development 2011)
Self-renewal and differentiation of spermatogonial stem cells derived from congenitally infertile mice
(Journal of mammalian ova research = 日本哺乳動物卵子学会誌 2010)
精原幹細胞の自己複製と分化の制御
(第33回阿蘇シンポジウム 2009)
精原幹細胞の増殖を調節する因子
(麻布大学雑誌 2008)

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Professional career (1)：

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