Suzuki Hiroka

Affiliation and department：

Research field (1)： Pharmacology

Research keywords (2)： TRPチャネル , イオンチャネル

Research theme for competitive and other funds (6)：

2022 - 2025 Mechanical stimulation exacerbates osteoarthritis (OA) by activating synovial fibroblasts.
2020 - 2023 Mechanosensitive PIEZO channel functions in cancer cells and their pathophysiological significance
2018 - 2020 Functional analysis of Piezo1, aimed to develop new therapeutic drug of liver fibrogenesis.
2014 - 2017 Transcriptional regulation of cation channels by iPS factors and the expression deficient diseases
2011 - 2013 Degradation of cation channel and the dysfunction

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Papers (15)：

Noriyuki Hatano, Masaki Matsubara, Hiroka Suzuki, Yukiko Muraki, Katsuhiko Muraki. HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn2+ Accumulation in Inflammatory Synoviocytes. International Journal of Molecular Sciences. 2021. 22. 12. 6349-6349
Yoneda M, Suzuki H, Hatano N, Nakano S, Muraki Y, Miyazawa K, Goto S, Muraki K. PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation. International journal of molecular sciences. 2019. 20. 19
Takahisa Suzuki, Yukiko Muraki, Noriyuki Hatano, Hiroka Suzuki, Katsuhiko Muraki. PIEZO1 channel is a potential regulator of synovial sarcoma cell-viability. International Journal of Molecular Sciences. 2018. 19. 5
Katsuhiko Muraki, Kaori Ohnishi, Akiho Takezawa, Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Nurasyikin Hamzah, Richard Foster, Herbert Waldmann, Peter Nussbaumer, et al. Na+ entry through heteromeric TRPC4/C1 channels mediates (-) Englerin A-induced cytotoxicity in synovial sarcoma cells. SCIENTIFIC REPORTS. 2017. 7. 1. 16988
Katsuhiko Muraki, Takashi Sekine, Yuna Ando, Hiroka Suzuki, Noriyuki Hatano, Tadashi Hirata, Yukiko Muraki. An environmental pollutant, 9,10-phenanthrenequinone, activates human TRPA1 via critical cysteines 621 and 665. Pharmacology Research and Perspectives. 2017. 5. 4

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MISC (4)：

Katsuhiko Muraki, Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Yuka Itoh, Hidetoshi Hayashi, Kikuo Onozaki. Potent activation of TRPA1 channel by NADPH oxidase inhibitors. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 171P-171P
Noriyuki Hatano, Yuka Itoh, Hiroka Suzuki, Yukiko Muraki, Hidetoshi Hayashi, Kikuo Onozaki, Ian Wood, David Beech, Katsuhiko Muraki. Inflammatory stimulation induces expression of TRPA1 channel to regulate cytokine release. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 158P-158P
Noriyuki Hatano, Yuka Itoh, Hiroka Suzuki, Yukiko Muraki, Hidetoshi Hayashi, Kikuo Onozaki, Ian Wood, David Beech, Katsuhiko Muraki. Transcriptional regulation of transient receptor potential ankyrin 1 channel gene expression by hypoxia inducible factor-1 alpha. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 234P-234P
Noriyuki Hatano, Erika Kusugami, Erina Kamiya, Hiroka Suzuki, Yukiko Muraki, Katsuhiko Muraki. Selective and potent activation of human TRPA1 by a disease modifying anti-rheumatic drug, auranofin. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 216P-216P

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