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J-GLOBAL ID：201901020340616185
Update date: Mar. 18, 2024
Komada Takanori
Komada Takanori
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Affiliation and department：
Jichi Medical University
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Research field (1)：
Nephrology
Research theme for competitive and other funds (6)：
2022 - 2024 低カリウム血症における自然免疫経路の役割
2021 - 2024 Role and Mechanism of a novel E3 ligase ARIH2 in Cardiovascular Disease
2021 - 2024 動脈硬化病変におけるカスパーゼ11依存的パイロトーシスの役割の解明
2020 - 2023 Acute-on-chronic腎障害における炎症細胞死の病態解明
2019 - 2022 Mechanism of NLRP3 inflammasome in CAWS-induced vasculitis
2019 - 2020 Mechanism of Acute Kidney Injury Induced by Remote organ injury
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Papers (47)：
Naoya Yamada, Tadayoshi Karasawa, Junya Ito, Daisuke Yamamuro, Kazushi Morimoto, Toshitaka Nakamura, Takanori Komada, Chintogtokh Baatarjav, Yuma Saimoto, Yuka Jinnouchi, et al. Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis. Nature communications. 2024. 15. 1. 2195-2195
Tadayoshi Karasawa, Takanori Komada, Chintogtokh Baatarjav, Emi Aizawa, Yoshiko Mizushina, Kenta Fujimura, Yoshitaka Gunji, Satoko Komori, Hidetoshi Aizawa, Cantona Billton Jing Tao, et al. Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice. Biochemical and biophysical research communications. 2023. 686. 149158-149158
Kenta Fujimura, Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Yoshiko Mizushina, Chintogtokh Baatarjav, Takayoshi Matsumura, Kinya Otsu, Norihiko Takeda, Hiroaki Mizukami, et al. NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy. Journal of molecular and cellular cardiology. 2023. 180. 58-68
Chintogtokh Baatarjav, Takanori Komada, Tadayoshi Karasawa, Naoya Yamada, Ariunaa Sampilvanjil, Takayoshi Matsumura, Masafumi Takahashi. dsDNA-induced AIM2 pyroptosis halts aberrant inflammation during rhabdomyolysis-induced acute kidney injury. Cell death and differentiation. 2022
Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Emi Aizawa, Yoshiko Mizushina, Sachiko Watanabe, Chintogtokh Baatarjav, Takayoshi Matsumura, Masafumi Takahashi. Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome. eLife. 2022. 11
ｍore...
MISC (4)：
Emi Aizawa, Tadayoshi Karasawa, Sachiko Watanabe, Takanori Komada, Hiroaki Kimura, Ryo Kamata, Homare Ito, Erika Hishida, Naoya Yamada, Tadashi Kasahara, et al. GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition. iScience. 2020. 23. 5. 101070-101070
秋山 裕輝, 増田 貴博, 岩本 澄也, 杉江 舜, 安部 翔, 松岡 諒, 宮本 友佳, 大舘 孝幸, 中川 早紀, 今井 利美, et al. 血液透析とECUMの除水量が浮腫値に及ぼす効果の比較検討. 日本透析医学会雑誌. 2019. 52. Suppl.1. 461-461
木村博昭, 木村博昭, 唐澤直義, 駒田敬則, 鎌田諒, 笠原忠, 高橋将文. 脂肪細胞分化における免疫プロテアソームの役割. 日本薬学会九州支部大会講演要旨集. 2019. 36th
Komada Takanori, Usui Fumitake, Muto Shigeaki, Nagata Daisuke, Kusano Eiji, Takahashi Masafumi. INFLAMMASOME ACTIVATION IN RENAL COLLECTING DUCT EPITHELIAL CELLS: THE POTENTIAL ROLE OF NON-IMMUNE CELLS IN RENAL INFLAMMATION AND FIBROSIS. NEPHROLOGY. 2014. 19. 30-31
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