Kurebayashi Yutaka

クレバヤシユタカ | Kurebayashi Yutaka

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://k-ris.keio.ac.jp/html/100002179_en.html

Research field (2)： Immunology , Human pathology

Research keywords (4)： Human Immunology , Human Pathology , Immunology , Pathology

Research theme for competitive and other funds (8)：

2021 - 2025 Study of the Immune Microenvironment of Hepatocellular Carcinoma at Different Clinical Stages
2023 - 2024 肝細胞癌の特徴的な腫瘍免疫・血管微小環境の形成機序の検討
2023 - 2024 免疫応答の発達・疲弊過程の時空間的変化を反映した腫瘍免疫微小環境の分類と患者層別化への応用
2022 - 2023 肝細胞癌の特徴的な腫瘍免疫・血管微小環境の形成機序の検討
2022 - 2023 進行がんの免疫・血管微小環境の多様性に関するリバーストランスレーショナル研究

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Papers (21)：

Sota Fujimori, Po-Sung Chu, Toshiaki Teratani, Yosuke Harada, Takahiro Suzuki, Takeru Amiya, Nobuhito Taniki, Ryosuke Kasuga, Yohei Mikami, Yuzo Koda, et al. IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis. JHEP Reports. 2023. 5. 7. 100757-100757
Yutaka Kurebayashi, Hanako Tsujikawa, Katsutoshi Sugimoto, Daisuke Yunaiyama, Yoichi Araki, Kazuhiro Saito, Hiroshi Takahashi, Tatsuya Kakegawa, Takuya Wada, Yusuke Tomita, et al. Tumor Steatosis and Glutamine Synthetase Expression in Patients with Advanced HCC Receiving Atezolizumab plus Bevacizumab Therapy. Hepatology Research. 2023. Accepted
Yutaka Kurebayashi, Kosuke Matsuda, Akihisa Ueno, Hanako Tsujikawa, Ken Yamazaki, Yohei Masugi, Wit Thun Kwa, Kathryn Effendi, Yasushi Hasegawa, Hiroshi Yagi, et al. Immuno-vascular Classification of HCC Reflects Reciprocal Interaction between Immune and Angiogenic Tumor Microenvironments. Hepatology. 2022. 75. 5. 1139-1153
Hisato Iriki, Hayato Takahashi, Naoko Wada, Hisashi Nomura, Miho Mukai, Aki Kamata, Hiromi Ito, Jun Yamagami, Takeshi Matsui, Yutaka Kurebayashi, et al. Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus. Proceedings of the National Academy of Sciences. 2021. 118. 49. e2026763118-e2026763118
H. Takahashi, H. Nomura, H. Iriki, A. Kubo, K. Isami, Y. Mikami, M. Mukai, T. Sasaki, J. Yamagami, J. Kudoh, et al. Cholesterol 25-hydroxylase is a metabolic switch to constrain T cell-mediated inflammation in the skin. Science Immunology. 2021. 6. 64. eabb6444

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MISC (14)：

紅林泰. 【微小環境から読み解く肝癌】免疫・血管微小環境に基づいた肝癌分類. 肝胆膵. 2024. 88. 4. 411-419
野阪拓人, 中本安成. Tumor-associated macrophages in hepatocellular carcinoma: from mechanisms to therapeutic targets. 肝胆膵. 2023. 86. 5. 573-578
紅林泰. 【薬物療法時代の肝細胞癌診断と治療】肝細胞癌における免疫微小環境の病理学的分類. 画像診断. 2023. 43. 3
紅林泰, 坂元亨宇. 免疫微小環境からみた肝細胞癌の多様性特集:進化する肝細胞癌の薬物療法:2022 update. 肝胆膵. 2022. 85. 3. 355-362
Yutaka Kurebayashi, Michiie Sakamoto. Immune microenvironment of CTNNB1-mutated hepatocellular carcinoma. 2021. 83. 2. 189-195

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Books (1)：

Treatment of Hepatocellular Carcinoma by Atezolizumab and Bevacizumab Combination Therapy
2021

Lectures and oral presentations (40)：

肝細胞癌における抗腫瘍免疫応答の形質・空間的全体像と複合免疫療法の治療効果との関係
(第60回日本肝臓学会(熊本) 2024)
肝細胞癌における抗腫瘍免疫応答の形質・空間的全体像の解明
(第113回日本病理学会総会(名古屋) 2024)
腫瘍内脂肪化とグルタミン合成酵素発現は進行肝細胞癌に対する複合免疫療法の治療効果予測因子である
(第59回日本肝癌研究会(大阪) 2023)
肝細胞癌における免疫微小環境の発達・疲弊過程の時空間的解析と原発巣・転移巣間多様性
(第59回日本肝癌研究会(大阪) 2023)
Classification of Immune and Immunovascular Tumor Microenvironment of Hepatocellular Carcinoma through Detailed Histopathological Analysis
(14th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland (Liverpool Pathology 2023) (Liverpool, UK) 2023)

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Education (3)：

2013 - 2017 Keio University School of Medicine, Tokyo, JAPAN Department of Pathology Ph.D. course
2005 - 2011 Keio University School of Medicine, Tokyo, JAPAN M.D. course
- 2005 静岡県立清水東高等学校

Professional career (2)：

M.D. (Keio University, Tokyo, JAPAN)
Ph.D. (Keio University, Tokyo, JAPAN)

Work history (9)：

2022/04 - 現在 Keio University School of Medicine, Tokyo, JAPAN Department of Pathology Assistant Professor
2020/09 - 2022/08 National Cancer Institute, National Institutes of Health, MD, USA Molecular Imaging Branch Special Volunteer
2017/04 - 2022/03 Keio University School of Medicine, Tokyo, JAPAN Department of Pathology Research Associate
2018/09 - 2020/09 National Cancer Institute, National Institutes of Health, Bethesda, MD, USA Molecular Imaging Branch Postdoctoral Fellow
2018/04 - 2018/08 National Hospital Organization Saitama Hospital, Saitama, JAPAN Department of Pathology Staff Pathologist

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Committee career (2)：

2023 - 現在肝癌症例検討会運営委員
2021/08 - 現在日本病理学会学術評議員

Awards (5)：

2023/07 - 肝臓フォーラム(東部) 大正Award(肝臓フォーラム(東部)奨励賞)
2022/05 - Keio University School of Medicine Alumni Association Young Investigator Award
2022/03 - 日本病理学会日本病理学会学術奨励賞
2016/05 - 日本病理学会日本病理学会100周年記念病理学研究新人賞ヒト腫瘍間質における免疫反応の網羅的な解析
2010/08 - 日本免疫学会日本免疫学会 Young Investigator’s Award

Association Membership(s) (8)：

肝癌症例検討会 , THE JAPANESE SOCIETY OF PATHOLOGY , Japanese Cancer Association , The Japanese Society for Lymphoreticular Tissue Research , The Japan Society of Hepatology , 日本肝癌研究会 , The Japanese Society of Clinical Cytology , AMERICAN ASSOCIATION FOR CANCER RESEARCH

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