Research field (5):
Plants: molecular biology and physiology
, Bioorganic chemistry
, Biochemistry
, Chemical biology
, Inorganic and coordination chemistry
Research theme for competitive and other funds (3):
2024 - 2027 Physiological significance of phenylethanoid glucosides accumulated in root parasitic plants
2022 - 2024 ケミカルバイオロジーと構造生物学の融合による花成の理解と制御
2021 - 2023 アロステリック機構に基づく14-3-3アイソフォーム選択的阻害剤の開発
Papers (7):
Kotaro Nishiyama, Yusuke Aihara, Takehiro Suzuki, Koji Takahashi, Toshinori Kinoshita, Naoshi Dohmae, Ayato Sato, Shinya Hagihara. Discovery of a Plant 14-3-3 Inhibitor Possessing Isoform Selectivity and In Planta Activity. Angewandte Chemie (International ed. in English). 2024. e202400218
Yusuke Takezawa, Keita Mori, Wei-En Huang, Kotaro Nishiyama, Tong Xing, Takahiro Nakama, Mitsuhiko Shionoya. Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases. Nature Communications. 2023. 14. 1
Kotaro Nishiyama, Keita Mori, Yusuke Takezawa, Mitsuhiko Shionoya. Metal-responsive reversible binding of triplex-forming oligonucleotides with 5-hydroxyuracil nucleobases. Chemical Communications. 2021. 57. 20. 2487-2490
Nishiyama, K, Takezawa, Y, Mashima, T, Katahira, M, Shionoya, M. Construction of metallo-DNA duplexes using 5-hydroxyuracil nucleobases as metal coordination site. Pacifichem 2015. 2015