Sasaki Takeshi

Affiliation and department：

Research field (1)： Urology

Research keywords (4)：間質細胞 , 癌微小環境 , 前立腺肥大症 , 前立腺癌

Research theme for competitive and other funds (9)：

2024 - 2027 Basic research for clinical application of patient-derived xenograft avatar model by zebrafish
2021 - 2024 Clinical application of patient-derived xenograft zebrafish model of bladder cancer for evaluating drug efficacy and discovering new seeds of treatment
2021 - 2024 Regulation of prostate cancer progression by transformation of cancer-associated fibroblasts.
2019 - 2022 Development of a novel diagnostic method for prostate cancer that targets tumor promoting fibroblast-derived exosomes
2018 - 2021 Investigation of novel prostate cancer diagnosis and treatment methods focusing lipid metabolism

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Papers (78)：

Yuki Yokoyama, Makoto Kawase, Shin Ebara, Tomoyuki Tatenuma, Takeshi Sasaki, Yoshinori Ikehata, Akinori Nakayama, Masahiro Toide, Tatsuaki Yoneda, Kazushige Sakaguchi, et al. Efficacy and safety of neoadjuvant chemohormonal therapy for high-risk prostate cancer treated with robot-assisted laparoscopic radical prostatectomy: a propensity score-matched analysis (the MSUG94 group). International urology and nephrology. 2024
Takeshi Sasaki, Takahiro Higashi, Takahiro Inoue. Urological cancer statistics on incidence from 1975 to 2019 and mortality from 1958 to 2022 in Japan. International journal of clinical oncology. 2024
Takeshi Sasaki, Ikuo Kobayashi, Katsunori Uchida, Shinichiro Higashi, Satoru Masui, Kouhei Nishikawa, Toyonori Tsuzuki, Masatoshi Watanabe, Naoto Sassa, Takahiro Inoue. Cribriform pattern 4/intraductal carcinoma of the prostate and persistent prostate-specific antigen after radical prostatectomy. BJUI compass. 2024. 5. 7. 709-717
Takahiro Inoue, Xin Bao, Takumi Kageyama, Yusuke Sugino, Sho Sekito, Shiori Miyachi, Takeshi Sasaki, Robert Getzenberg. Purine-Rich Element Binding Protein Alpha, a Nuclear Matrix Protein, Has a Role in Prostate Cancer Progression. International journal of molecular sciences. 2024. 25. 13
Remi Semba, Katsunori Uchida, Yoshihumi Hirokawa, Taizo Shiraishi, Takehisa Onishi, Takeshi Sasaki, Takahiro Inoue, Masatoshi Watanabe, Hiroshi Miyamoto. A simple risk stratification model for prostate cancer using histopathologic findings of radical prostatectomy. American journal of clinical pathology. 2024

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MISC (12)：

Mikiya Ishihara, Yasutaka Tono, Yoshihiro Miyahara, Naozumi Harada, Shinichi Kageyama, Takeshi Sasaki, Yasuhide Hori, Norihito Soga, Katsunori Uchida, Taizo Shiraishi, et al. First-in-human phase I clinical trial of NY-ESO-1 protein cancer vaccine with a novel adjuvant MIS416, NOD2 and TLR9 stimulant, for patients with NY-ESO-1 expressing solid tumors. JOURNAL OF CLINICAL ONCOLOGY. 2018. 36. 15
Manabu Kato, Takeshi Sasaki, Kenichirou Ishii, Manabu Miki, Kohei Nishikawa, Kiminobu Arima, Taizo Shiraishi, Neil Bhowmick, Yoshiki Sugimura. THE EXPLORATION OF THE ORDER IN THE HETEROGENEITY OF PROSTATE CANCER-ASSOCIATED STROMA ENVIRONMENT. JOURNAL OF UROLOGY. 2016. 195. 4. E818-E819
Takehisa Onishi, Takuji Shibahara, Satoru Masui, Yusuke Sugino, Takeshi Sasaki. RANDOMIZED CONTROLLED STUDY OF THE EFFICACY AND SAFETY OF CONTINUOUS SALINE BLADDER IRRIGATION AFTER TRANSURETHRAL RESECTION FOR THE TREATMENT OF NON-MUSCLE INVASIVE BLADDER CANCER. JOURNAL OF UROLOGY. 2016. 195. 4. E287-E287
Takeshi Sasaki, Kenichiro Ishii, Manabu Miki, Hideki Kanda, Kiminobu Arima, Taizo Shiraishi, Yoshiki Sugimura. FIBROBLASTS PROLONG SERUM PROSTATE-SPECIFIC ANTIGEN DECLINE AFTER ANDROGEN DEPRIVATION THERAPY IN PROSTATE CANCER. JOURNAL OF UROLOGY. 2016. 195. 4. E818-E818
Kenichiro Ishii, Takeshi Sasaki, Manabu Miki, Manabu Kato, Hideki Kanda, Kiminobu Arima, Taizo Shiraishi, Yoshiki Sugimura. A NEW INSIGHT OF CELL-CELL INTERACTIONS IN TUMOR STROMA OF PROSTATE CANCER. JOURNAL OF UROLOGY. 2016. 195. 4. E819-E819

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Books (4)：

PARP阻害薬と免疫チェックポイント阻害薬
臨床泌尿器科 Vol77 No.11 p. 902-907 2023
陰茎癌
泌尿器科のくすり日本医事新報社 2022
去勢抵抗性前立腺がん:新規ホルモン剤治療再燃(化学療法導入)
泌尿器Care&Cure Uro-Lo Volume 26, Issue 3, 397 - 403 2021
Male Reproductive Tract:Prostate-Overview
Encyclopedia of Reproduction (Second Edition) 2018 Volume 1, 2018, Pages 309-314 2018

Lectures and oral presentations (6)：

前立腺癌におけるイン・シリコ解析を用いたGleason scoreの生物学的特徴に関する検討
(第62回日本癌治療学会学術集会 2024)
ロボット支援根治的前立腺全摘除術の手術日再発に対する篩状癌/前立腺導管内癌(CC/IDCP)の影響に関する検討
(第111回日本泌尿器科学会総会 2024)
日本人大規模コホートにおけるRARP病理学的Grade Group5前立腺癌患者の予後因子の検討
(第61回日本癌治療学会学術集会 2023)
高-超高リスク前立腺癌における予後改善を目指した手術、周術期治療の可能性を探る
(第73回日本泌尿器科学会中部総会 2023)
三重大学医学部附属病院で施行した、去勢抵抗性前立腺癌57例の遺伝子パネル検査の検討
(第110回日本泌尿器科学会総会 2023)

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Professional career (1)：

博士(医学) (三重大学)

Committee career (1)：

2023/07 - 現在日本泌尿器科学会 International Journal of Urology Deputy Editor

Awards (7)：

2018/12 - 三医会・公益財団法人三重医学研究振興会三重医学若手研究者賞受賞
2018/05 - The 2018 American Urological Association (AUA)総会 Best of posters
2015/09 - 公益財団法人中山人間科学振興財団国際交流助成(海外渡航)受賞
2013/10 - 公益社団法人三重県医師会医学研究奨励賞受賞
2013/03 - 公益財団法人三重県健康管理事業センター学術助成金受賞

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