Koyama Shohei

コヤマショウヘイ | Koyama Shohei

Affiliation and department：
Job title： Chief

Research field (2)： Tumor biology , Respiratory medicine

Research keywords (1)： cancer immunology and cancer immunotherapy

Research theme for competitive and other funds (9)：

2024 - 2027 線維化を背景とした肺がん発症に関する基盤的解析
2022 - 2025 Regulation of myeloid-derived suppressor cells by palmitic acid metabolism for next-generation cancer immunotherapy
2021 - 2024 Basic evaluation and investigation of the factors linked to the long term response to immunotherapies
2020 - 2023 Development of novel cancer therapy based on promotion of tumor infiltrating lymphocyte by the immunomodulation with ultrasound technology
2020 - 2022 ダイレクトリプログラミング技術を用いた新しい線維化疾患治療法の開発

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Papers (171)：

Kosuke Tanaka, Yasuki Adachi, Miyuki Yoshiya, Takuya Owari, Tomoko Yamamori-Morita, Akihiro Ohashi, Susumu Kobayashi, Shohei Koyama, Hiroyoshi Nishikawa. Abstract 5265: Targeting mtDNA dynamics enhances immunogenicity and sensitizes KRAS mutant cancers to PD-1 blockade. Cancer Research. 2024. 84. 6_Supplement. 5265-5265
Shogo Takei, Yosuke Tanaka, Yi-Tzu Lin, Shohei Koyama, Shota Fukuoka, Hiroki Hara, Yoshiaki Nakamura, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, et al. Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal cancer. Journal for immunotherapy of cancer. 2024. 12. 2
Takashi Hirai, Yujiro Naito, Shohei Koyama, Yoshimitsu Nakanishi, Kentaro Masuhiro, Mayuko Izumi, Tomoki Kuge, Maiko Naito, Yumiko Mizuno, Yuta Yamaguchi, et al. Sema6D forward signaling impairs T cell activation and proliferation in head and neck cancer. JCI insight. 2024. 9. 3
Shingo Satoh, Kotaro Miyake, Yuichi Adachi, Kentaro Masuhiro, Shinji Futami, Yujiro Naito, Takayuki Shiroyama, Shohei Koyama, Yuta Yamaguchi, Hachiro Konaka, et al. Cancer-associated SNRPD3 mutation confers resistance to hypoxia, which is attenuated by DRP1 inhibition. Biochemical and biophysical research communications. 2024. 696. 149511-149511
刀祢麻里, 岩堀幸太, 白井雄也, 高田創, 益弘健太朗, 内藤真依子, 内藤祐二朗, 福島清春, 白山敬之, 三宅浩太郎, et al. EGFR遺伝子変異陽性肺癌患者におけるミノサイクリン内服の予後への影響. 肺癌. 2023. 63. 5. 600-600

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MISC (93)：

加藤吏恵, 宗像理紗, 青枝大貴, 小山正平, 小山正平, 小俣大樹, 鈴木悠乃, 岡田欣晃, 吉岡靖雄, 吉岡靖雄, et al. Development of effective cancer immunotherapy for Cold tumor. 日本薬学会年会要旨集(Web). 2023. 143rd
山本悠司, 平田陽彦, 白山敬之, 久下朋輝, 松本錦之介, 米田翠, 山本真, 内藤祐二朗, 菅泰彦, 福島清春, et al. Evaluation of ventilation and diffusing capacity using oscillometry in patients with idiopathic pulmonary fibrosis combined with emphysema. 日本呼吸器学会誌(Web). 2023. 12
熊谷尚悟, 小山正平, 板橋耕太, 冨樫庸介, 吉田達哉, 石井源一郎, 河津正人, 山崎直也, 坪井正博, 谷田部恭, et al. 腫瘍微小環境における制御性T細胞に特徴的な代謝学的チェックポイントの同定(Identification of a distinctive metabolic checkpoint of regulatory T cells in the tumor microenvironment). 日本癌学会総会記事. 2022. 81回. CES1-3
小山正平, 西川博嘉. 【がん免疫療法研究の進歩】がん免疫応答を制御する免疫細胞の解明制御性T細胞による免疫応答調節. 腫瘍内科. 2022. 29. 2. 168-172
宗像理紗, 小俣大樹, 小山正平, 岡田欣晃, 吉岡靖雄, 青枝大貴, 鈴木亮. Study of novel antitumor immunotherapy via immunomodulation of tumor microenvironment. 日本核酸医薬学会年会講演要旨集(CD-ROM). 2022. 7th

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Work history (2)：

2024/04 - 現在 National Cancer Center Department of Immuno-genomic Medicine, Research Institute Chief
2020/04 - 2024/04 National Cancer Center Division of Cancer Immunology, Research Institute/Exploratory Oncology Research and Clinical Trial Center Unit leader

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