NAKAJIMA HIROYUKI

ナカジマヒロユキ | NAKAJIMA HIROYUKI

Affiliation and department：
Job title：室長

Research field (1)： Developmental biology

Research keywords (5)：血管形成 , 生体イメージング , メカニカルストレス , ゼブラフィッシュ , 血管新生

Research theme for competitive and other funds (21)：

2024 - 2028 血管-上皮相互作用による酸素交換場形成の共通原理の解析
2023 - 2028 血管が主導する新たな組織形成機構の解明
2023 - 2027 脈管系物流の破綻に伴う全身老化過程の解明
2020 - 2024 Development and validation of mathematical model of nanomedicine for cancer treatment by using zebrafish
2019 - 2024 Clarifying left-right asymmetry by imaging of cell signaling and tissue development

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Papers (29)：

Ayano Chiba, Takuya Yamamoto, Hajime Fukui, Moe Fukumoto, Manabu Shirai, Hiroyuki Nakajima, Naoki Mochizuki. Zonated Wnt/β-catenin signal-activated cardiomyocytes at the atrioventricular canal promote coronary vessel formation in zebrafish. Developmental cell. 2024
Nanami Morooka, Ning Gui, Koji Ando, Keisuke Sako, Moe Fukumoto, Urara Hasegawa, Melina Hußmann, Stefan Schulte-Merker, Naoki Mochizuki, Hiroyuki Nakajima. Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish. Development. 2024. 151. 10
Melina Hußmann, Dörte Schulte, Sarah Weischer, Claudia Carlantoni, Hiroyuki Nakajima, Naoki Mochizuki, Didier Y R Stainier, Thomas Zobel, Manuel Koch, Stefan Schulte-Merker. Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner. eLife. 2023. 12
Hiroyuki Nakajima, Hiroyuki Ishikawa, Takuya Yamamoto, Ayano Chiba, Hajime Fukui, Keisuke Sako, Moe Fukumoto, Kenny Mattonet, Hyouk-Bum Kwon, Subhra P. Hui, et al. Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish. Developmental Cell. 2023. 58. 3. 1-15
Yusuke Nishimura, Tomohiro Ishii, Koji Ando, Shinya Yuge, Hiroyuki Nakajima, Weibin Zhou, Naoki Mochizuki, Shigetomo Fukuhara. Blood Flow Regulates Glomerular Capillary Formation in Zebrafish Pronephros. Kidney360. 2022. 3. 4. 700-713

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MISC (2)：

Fukuhara Shigetomo, Yuge Shinya, Kunita Itsuki, Wakayama Yuki, Nakajima Hiroyuki, Nishiyama Koichi, Mochizuki Naoki. Role of mechanotransduction in angiogenesis. Transactions of Japanese Society for Medical and Biological Engineering. 2016. 54Annual. 28PM-Abstract. S327-S327
Vascular Maturation and Stabilization Mediated by Endothelial Cell-specific Signaling and Endothelial Cell-mediated Adhesions. 2013. 68. 12. 2615-2620

Books (8)：

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Lectures and oral presentations (45)：

Unveiling Circulatory Organ Development and Homeostasis through In Vivo Fluorescence Imaging
(2024)
Angpt1/Tie1 signaling regulates lymphatic vessel development in zebrafish
(2024)
ゼブラフィッシュ蛍光イメージングを用いた血管多様性創出機構
(第9回血管生物医学会若手研究会 2024)
小型魚類の生体イメージングを用いた循環臓器構築原理の解析
(浜松医科大学生理学セミナー 2024)
血管・上皮のin vivoイメージングによるガス交換場形成機構の解析
(第101回日本生理学会大会シンポジウム『高深度生理学~循環器編~』 2024)

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Education (2)：

Work history (9)：

2024/04 - 現在京都大学大学院薬学研究科講師(非常勤)
2017/05 - 現在 National Cerebral and Cardiovascular Center, Research Institute
2022/04 - 2022/09 京都大学大学院薬学研究科講師(非常勤)
2020/04 - 2020/09 Kyoto University
2015/04 - 2017/04 National Cerebral and Cardiovascular Center Research Institute

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Committee career (5)：

Awards (11)：

2021 - The 5th JCS Council Forum on Basic CardioVascular Research BCVR Best Abstract Award
2020 - 血管生物医学会若手優秀賞
2019 - Inaugural Joint Scientific Meeting of AVBS | ANZMS | AAVBM (Sydney) Travel Award
2019 - 血管生物医学会若手最優秀賞
2018 - International Vascular Biology Meeting 2018 (IVBM 2018) (Helsinki) JVBMO Travel Award

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Association Membership(s) (6)：

日本循環器学会 , 国際心臓研究学会(ISHR)日本部会 , 日本生化学会 , 日本血管生物医学会 , 日本細胞生物学会 , 日本分生生物学会

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