Rchr
J-GLOBAL ID：202001001120768835   Update date: Oct. 28, 2024

Kanki Keita

カンキ ケイタ | Kanki Keita
Affiliation and department：
岡山理科大学 工学部 生命医療工学科

About 岡山理科大学 工学部 生命医療工学科


Job title： 准教授
Research field  (2)： Biomaterials ,  Tumor biology
Research keywords  (3)： regenerative medicine ,  cancer ,  cell differentiation
Research theme for competitive and other funds  (10)：
  • 2022 - 2025 細胞死抑制技術によるハイバイアビリティ細胞凝集体の創製と組織工学への応用
  • 2018 - 2021 立体臓器チップ構築に向けた細胞単層の自動3D化技術の基盤開発
  • 2018 - 2021 Development of anti-cancer strategy using IDH gene activation
  • 2014 - 2016 Gene expression analysis of tumor-antigen PRAME in hepatocellular carcinoma and its possible involvement in tumor progression
  • 2013 - 2015 Enhancing effect of retinoids on anti-cancerous drugs by regulating intracellular molecules
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Papers (47)：
  • Takuro Matsumura, Yasuharu Ohta, Akihiko Taguchi, Syunsuke Hiroshige, Yasuko Kajimura, Naofumi Fukuda, Kaoru Yamamoto, Hiroko Nakabayashi, Ruriko Fujimoto, Akie Yanai, et al. Liver-specific dysregulation of clock-controlled output signal impairs energy metabolism in liver and muscle. Biochemical and biophysical research communications. 2021. 534. 415-421
  • Keita Kanki, Ryota Watanabe, Le Nguyen Thai, Chun-Hao Zhao, Kyoko Naito. HDAC9 Is Preferentially Expressed in Dedifferentiated Hepatocellular Carcinoma Cells and Is Involved in an Anchorage-Independent Growth. Cancers. 2020. 12. 10
  • Kyoko Naito, Keita Kanki. Glycolytic inhibition by resveratrol prevents myoblast cell death caused by glucose deprivation and hypoxia; a possible application to the three-dimensional tissue construction. Journal of bioscience and bioengineering. 2020
  • Kensuke Harada, Ryuya Ohashi, Kyoko Naito, Keita Kanki. Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling. International journal of molecular sciences. 2020. 21. 9
  • Xian-Yang Qin, Harukazu Suzuki, Masao Honda, Hikari Okada, Shuichi Kaneko, Ikuyo Inoue, Etsuko Ebisui, Kosuke Hashimoto, Piero Carninci, Keita Kanki, et al. Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid. Proceedings of the National Academy of Sciences of the United States of America. 2018. 115. 19. 4969-4974
ｍore...
MISC (4)：
  • 太田 康晴, 田口 昭彦, 松村 卓郎, 藤本 留理子, 秋山 優, 福田 尚文, 山本 薫, 神吉 けい太, 汐田 剛史, 水上 洋一, et al. 糖尿病・糖尿病合併症発症機序における臓器連関 体内時計による代謝制御と糖尿病. 糖尿病. 2020. 63. Suppl.1. S-81
  • 太田 康晴, 松村 卓郎, 田口 昭彦, 福田 尚文, 山本 薫, 柳井 章江, 秋山 優, 藤本 留理子, 神吉 けい太, 汐田 剛史, et al. 出力系時計遺伝子E4BP4の肝特異的過剰発現は骨格筋でのインスリン感受性を低下させる. 糖尿病. 2020. 63. Suppl.1. S-342
  • 太田 康晴, 田口 昭彦, 松村 卓郎, 福田 尚文, 山本 薫, 柳井 章江, 秋山 優, 藤本 留理子, 神吉 けい太, 汐田 剛史, et al. 時間生物学からみた生活習慣病の病態 Circadian Dysregulationによるインスリン分泌不全と肝インスリン抵抗性. 糖尿病. 2018. 61. Suppl.1. S-91
  • Goshi Shiota, Hiroki Shimizu, Keita Kanki. Suppression of glycolysis by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib via AMPK activation. CANCER RESEARCH. 2015. 75
Professional career (1)：
  • 博士(理学) (北海道大学)
Work history (7)：
  • 2015/04 - 現在 Okayama University of Science Faculty of Engineering, Department of Biomedical Engineering Associate professor
  • 2010/04 - 2015/03 Tottori University Graduate School of Medical Sciences Major in Regenerative Medicine and Biofunction Assistant Professor
  • 2009/04 - 2010/03 Institute of Medical Science, the University of Tokyo Laboratory Animal Research Center Postdoctoral Researcher
  • 2006/05 - 2009/03 Musashino University Research Institute of Pharmacy Postdoctoral Researcher
  • 2006/01 - 2006/03 National Institute of Health Sciences Division of Medical Safety Science Postdoctoral Researcher
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