Mizutani Tomohiro

ミズタニトモヒロ | Mizutani Tomohiro

Affiliation and department：
Homepage URL (1)： https://scholar.google.com/citations?hl=ja&user=vRq2zX4AAAAJ&view_op=list_works&gmla=AJsN-F6VJ5rUI_DzIjutZvCRugn7OeIXTqyiBswzkWUK3dXgXxbc3CBQR2YiZVcKqRjqFadjOhyDuEjpXHlPpMOqSn784cKs6m3yh5A2xkbB7u2exxGsnuUWyOveC-ymwZqjk1PBGGcpMQ1twyMnW-D9yariGjH_9Sc6bGJWJX4SQjugSAql_P4sRsa3OvpxBkL6yUR60GBL5bIyU2iammBvp9TPT49gKA

Research field (1)： Gastroenterology

Research theme for competitive and other funds (7)：

2022 - 2028 上皮細胞サーキュレーションによる疾患制御イノベーション
2022 - 2025 疾患/臓器/領域レベルでのアナジー誘導性抗原提示細胞;DNT細胞研究の拡大
2022 - 2025 難治性消化管疾患に対する統合オルガノイド医療の創成
2022 - 2025 患者由来大腸オルガノイド移植法を用いたdysplasia-PDOXモデルの開発
2021 - 2024 ヒトiPS細胞由来複合型自己組織化腸管組織を用いた難治性腸炎モデルの確立

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Papers (38)：

Tomohiro Mizutani, Matteo Boretto, Sangho Lim, Jarno Drost, Diego Montiel González, Rurika Oka, Maarten H. Geurts, Harry Begthel, Jeroen Korving, Johan H. van Es, et al. Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids. Nature Cancer. 2024
Yuki Yonemoto, Yasuhiro Nemoto, Ryo Morikawa, Nana Shibayama, Shigeru Oshima, Takashi Nagaishi, Tomohiro Mizutani, Go Ito, Satoru Fujii, Ryuichi Okamoto. Single cell analysis revealed that two distinct, unique CD4+ T cell subsets were increased in the small intestinal intraepithelial lymphocytes of aged mice. Frontiers in immunology. 2024. 15. 1340048-1340048
Junichi Takahashi, Hady Yuki Sugihara, Shu Kato, Sayaka Nagata, Ryuichi Okamoto, Tomohiro Mizutani. Protocol to generate large human intestinal organoids using a rotating bioreactor. STAR protocols. 2023. 4. 3. 102374-102374
Satoshi Watanabe, Nobuhiko Ogasawara, Sakurako Kobayashi, Sakura Kirino, Masami Inoue, Yui Hiraguri, Sayaka Nagata, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, et al. Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment. Journal of gastroenterology. 2023. 58. 4. 379-393
Ryuichi Okamoto, Tomohiro Mizutani, Hiromichi Shimizu. [Pathology and treatment of inflammatory bowel disease from the perspective of stem cells]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 2023. 120. 7. 562-570

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MISC (37)：

岡本隆一, 水谷知裕, 藤井悟, 清水寛路. Regenerative medicine in inflammatory bowel disease. 月刊メディカル・サイエンス・ダイジェスト. 2024. 50. 3
岡本隆一, 水谷知裕, 清水寛路. Advancing Gastrointestinal Regenerative Medicine Through Organoids. 実験医学. 2024. 42. 5
清水寛路, 水谷知裕, 水谷知裕, 岡本隆一, 岡本隆一. 感染症を鑑別したあとは?非感染性腸炎を見極める!炎症性腸疾患治療の最新情報大腸オルガノイド移植療法の実際. 診断と治療. 2024. 112. 3
岡本隆一, 岡本隆一, 水谷知裕, 清水寛路, 清水寛路. Development of intestinal organoid-based therapy for inflammatory bowel disease. 実験医学. 2023. 41. 2
清水寛路, 水谷知裕, 岡本隆一. 炎症性腸疾患に対する再生医療の現状. 日本消化器病学会雑誌(Web). 2023. 120

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Education (2)：

- 2012 Tokyo Medical and Dental University
- 2005 東京医科歯科大学医学部医学科

Professional career (1)：

医学博士 (東京医科歯科大学)

Work history (1)：

2022/04 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences

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