Rchr
J-GLOBAL ID:202001001320480151
Update date: May. 02, 2024
Inomata Megumi
イノマタ メグミ | Inomata Megumi
Affiliation and department:
Research field (1):
Oral medicine (pathology)
Research keywords (3):
歯周病
, 自然免疫
, オートファジー
Research theme for competitive and other funds (11):
- 2023 - 2026 Candida albicansの「形態変化」が歯周炎の病態に及ぼす影響の解析
- 2021 - 2024 長鎖ノンコーディングRNA Malat1による分枝形態形成の調節機構の解明
- 2021 - 2024 Identification of unknown virulence factors in dental plaque and elucidation of its effects on periodontitis and aspiration pneumonia
- 2018 - 2021 The effect of age-related attenuation of autophagy on pneumonia and aspiration pneumonia
- 2016 - 2019 Search and characterization of glycosylation-related enzymes of outer membrane proteins from periodantal bacteria
- 2015 - 2019 Pathogenicity of OmpA-like protein of periodontopathic bacteria to the host cells
- 2013 - 2015 The elucidation of the effect of innate immune signaling on production of antimicrobial factors by salivary glands
- 2011 - 2014 Regulatory effect of the TLR/TACI-MyD88 signaling pathway on immune responses associated with the homing of IgA-producing B cells into salivary glands
- 2011 - 2013 Post-translational modifications of proteins from periodontpathic bacteria: role of glycosylation and phosphorylation
- 2011 - 2012 The elucidation of the role of'autophagy receptor'in immune mechanism of oral epithelium cells
- 2009 - 2010 Investigation of pathological effects of periodontopathic bacteria on endothelial cells forming capillary-like tube networks
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Papers (29):
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MEGUMI INOMATA, MASAYO ABE, YASUKO KAWASE, TORU HAYASHI, SHIGERU AMANO, HIROSHI SAKAGAMI. Dectin-1/SYK Activation Induces Antimicrobial Peptide and Negative Regulator of NF-κB Signaling in Human Oral Epithelial Cells. In Vivo. 2024. 38. 3. 1042-1048
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Maki Izawa, Yusei Otaka, Hiroshi Sakagami, Sei-Ichi Tanuma, Shigeru Amano, Shin Uota, Megumi Inomata, Yuka Kato, Hiroshi Kadokura, Satoshi Yokose, et al. Comprehensive Study of Anti-UVC Activity and Cytotoxicity of Hot-water Soluble Herb Extracts. In vivo (Athens, Greece). 2023. 37. 4. 1540-1551
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Yusei Otaka, Maki Izawa, Hiroshi Sakagami, Noriyoshi Shiba, Nobutoshi Takahashi, Sei-Ichi Tanuma, Shigeru Amano, Shin Uota, Megumi Inomata, Satoshi Yokose, et al. UVC-Protective Activity of Lemongrass Among 12 Fat-soluble Herbal Extracts: Rapid Decay Due to Cytotoxicity. In vivo (Athens, Greece). 2023. 37. 6. 2464-2472
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Megumi Inomata, Shigeru Amano, Masayo Abe, Toru Hayashi, Hiroshi Sakagami. Innate immune response of human periodontal ligament fibroblasts via the Dectin-1/Syk pathway. Journal of Medical Microbiology. 2022. 71. 12
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Ayaka Shindo, Midori Kusano, Hiroshi Sakagami, Shigeru Amano, Megumi Inomata, Masayo Abe, Masashi Okazawa, Takafumi Ooka. Comparison of UVC Sensitivity and Dectin-2 Expression Between Malignant and Non-malignant Cells. In vivo (Athens, Greece). 2022. 36. 5. 2116-2125
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MISC (8):
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坂上 宏, 安部 雅世, 猪俣 恵, 魚田 慎, 天野 滋, 田沼 靖一. バニリンの卓越したUVC保護効果およびデクチン-2の発現との相関(Prominent UVC protective effect of vanillin and its relation to dectin-2 expression). Journal of Oral Biosciences Supplement. 2022. 2022. 203-203
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Analysis of mecA-positive staphylococci detected from the students of Asahi University and inferences of propagation of mecA gene among commensal staphylococci. 2020. 47. 1. 21-28
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Effect of the inhibitors for protein glycosylation-associated enzymes on the growth of the periodontopathic bacterium Porphyromonas gingivalis. 2019. 45. 3. 141-148
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OmpA-like proteins of Porphyromonas gingivalis contribute to serum resistance. 2018. 48. 2. 65-71
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Detection of mecA-positive staphylococci among the students of Asahi University and investigation of their dissemination during adolescence. 2017. 44. 1. 65-71
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Education (2):
- 2005 - 2009 愛知学院大学大学院 歯学研究科 歯周病学専攻
- 1999 - 2005 愛知学院大学 歯学部 歯学科
Work history (6):
Awards (3):
- 2020 - 日本嫌気性菌感染症学会 日本嫌気性菌感染症学会奨励賞
- 2008/09 - New Clinical Impact Award
- 2007/08 - 歯科基礎医学会 優秀ポスター賞 (微生物学部門)
Association Membership(s) (5):
日本免疫学会
, 国際歯科研究学会
, 日本歯周病学会
, 歯科基礎医学会
, 日本細菌学会
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