Hiyoshi Hirotaka

ヒヨシヒロタカ | Hiyoshi Hirotaka

Affiliation and department：
Job title： Associate Professor
Research theme for competitive and other funds (9)：

2022 - 2025 Epidemiological and pathogenicity analyses of invasive Salmonella based on genomics approach in Asia
2021 - 2024 ネズミチフス菌のエフェロサイトーシスを利用した生存戦略
2023 - 2024 Analysis virulence factors of S Typhi by using an alternative mouse infection model
2023 - 2024 Development of a scRNA-seq technique which capable of recognizing infected and uninfected cells.
2021 - 2024 ネズミチフス菌のT3SS-2を介した新規全身感染機構の解析

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Papers (24)：

Lillian F. Zhang, Bernd Lepenies, Sayuri Nakamae, Briana M. Young, Renato L. Santos, Manuela Raffatellu, Brian A. Cobb, Hirotaka Hiyoshi, Andreas J. Bäumler. The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN. mBio. 2022. 13. 6
Megan J. Liou, Brittany M. Miller, Yael Litvak, Henry Nguyen, Dean E. Natwick, Hannah P. Savage, Jordan A. Rixon, Scott P. Mahan, Hirotaka Hiyoshi, Andrew W.L. Rogers, et al. Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes. Cell Host & Microbe. 2022. 30. 6. 836-847
Hirotaka Hiyoshi, Bevin C English, Vladimir E Diaz-Ochoa, Tamding Wangdi, Lillian F Zhang, Miako Sakaguchi, Takeshi Haneda, Renée M Tsolis, Andreas J Bäumler. Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis. Cell Host & Microbe. 2022. 30. 2. 163-170
Shigeaki Matsuda, Hirotaka Hiyoshi, Sarunporn Tandhavanant, Toshio Kodama. Advances on Vibrio parahaemolyticus research in the postgenomic era. Microbiology and immunology. 2020. 64. 3. 167-181
Shigeaki Matsuda, Ryu Okada, Sarunporn Tandhavanant, Hirotaka Hiyoshi, Kazuyoshi Gotoh, Tetsuya Iida, Toshio Kodama. Export of a Vibrio parahaemolyticus toxin by the Sec and type III secretion machineries in tandem. Nature microbiology. 2019. 4. 5. 781-788

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Lectures and oral presentations (7)：

Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding DC-SIGN.
(第96回細菌学会総会, 姫路, 3月16-18日, 2023.)
Virulence factors perforate the pathogen-containing vacuole to generate a find-me signal for efferocytosis.
(US-Japan Cooperative Medical Science Program Cholera and Other Bacterial Enteric Infections Annual Meeting, Manila, The Philippines, March 9-10, 2023.)
The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN.
(第51回免疫学会総会, 熊本, 12月7-9日, 2022.)
チフス菌のVi抗原を介した侵襲感染性発揮機構の解析.
The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN.
(The 20th Awaji International Forum on Infection and Immunity 2022Osaka, Japan, September 7-9, 2022.)

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Professional career (1)：

Work history (6)：

2023/08 - 現在 University of California at Davis Visiting Associate Professor
2022/02 - 現在 Nagasaki University Institute of Tropical Medicine Associate Professor
2020/09 - 2022/01 Nagasaki University Institute of Tropical Medicine Assistant Professor
2016/04 - 2020/08 University of California at Davis Assistant Project Scientist
2013/04 - 2016/03 University of California at Davis Postdoc

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Awards (4)：

2022 - Nagasaki University Award for impact publication
2016 - Japanese Society for Bacteriology Kuroya Award
2012 - Japanese Society for Symposium on Toxins Young Researcher’s Award
2010 - Osaka University Award for Exceptional Academic Excellence in the Doctor Course

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