Hiyoshi Hirotaka

ヒヨシヒロタカ | Hiyoshi Hirotaka

Affiliation and department：
Job title： Associate Professor
Research theme for competitive and other funds (12)：

2024 - 2029 ネズミチフス菌のT3SS-2を介した新規全身感染機構の解析
2024 - 2027 新規scRNA-seq技術を用いたサルモネラ3型分泌装置による宿主免疫防御機構再構成の解析
2024 - 2025 固定組織シングルセルRNA-seq技術を用いたサルモネラ病原因子による宿主免疫細胞再構成の網羅的解析
2023 - 2025 Analysis virulence factors of S Typhi by using an alternative mouse infection model
2022 - 2025 Epidemiological and pathogenicity analyses of invasive Salmonella based on genomics approach in Asia

Show all

Papers (26)：

Purity Kasiano, Masatomo Morita, Toshio Kodama, Hirotaka Hiyoshi, Susan Kavai, Susan Kiiru, Samuel Kariuki. Salmonella Typhi genotypic diversity, cluster identification and antimicrobial resistance determinants in Mukuru settlement, Nairobi Kenya. BMC Infectious Diseases. 2024. 24. 1
日吉大貴, アルカディ・ムハッマド, 山下舞花, 奥崎大介, 児玉年央. 病原体-宿主間ノン・セルフ認識の新潮流(New trends in "self- and non-self-recognition" recognition in host-pathogen interactions A new single-cell RNA-seq approach to analyze interaction of Salmonella to host immune system). 日本細菌学雑誌. 2024. 79. 2. 40-40
Lillian F. Zhang, Bernd Lepenies, Sayuri Nakamae, Briana M. Young, Renato L. Santos, Manuela Raffatellu, Brian A. Cobb, Hirotaka Hiyoshi, Andreas J. Bäumler. The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN. mBio. 2022. 13. 6
Megan J. Liou, Brittany M. Miller, Yael Litvak, Henry Nguyen, Dean E. Natwick, Hannah P. Savage, Jordan A. Rixon, Scott P. Mahan, Hirotaka Hiyoshi, Andrew W.L. Rogers, et al. Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes. Cell Host & Microbe. 2022. 30. 6. 836-847
Hirotaka Hiyoshi, Bevin C English, Vladimir E Diaz-Ochoa, Tamding Wangdi, Lillian F Zhang, Miako Sakaguchi, Takeshi Haneda, Renée M Tsolis, Andreas J Bäumler. Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis. Cell Host & Microbe. 2022. 30. 2. 163-170

ｍore...

Books (2)：

Salmonella Typhimurium hijacks host “efferocytosis” to survive in neutrophil.
The CELLL (the New Science Co., Ltd.) 2023
VopV, an F-actin-binding type III secretion effector, is required for Vibrio parahaemolyticus-induced enterotoxicity.
2011

Lectures and oral presentations (12)：

A single-cell RNA-seq approach to analyze the interaction of Salmonella with the host immune system.
(The 22nd Awaji international Forum on Infection and Immunity 2024, Kyoto, September 17-19, 2024.)
A new single-cell RNA-seq approach to analyze interaction of Salmonella to host immune system.
(第97回日本細菌学会総会, 札幌, 8月7-9日, 2024.)
Salmonella manipulates neutrophil activity and heterogeneity using the virulence factor T3SS-2.
Analysis of the host immune cell heterogeneity during Salmonella infection through single-cell RNA sequencing.
(Robert Koch Prize Symposium, USA, May 30-31, 2024.)
An alternative S. Typhi mouse infection model.
(Gordon Research Conference (GRC) Salmonella Biology and Pathogenesis, Italy, July 24-28, 2023.)

ｍore...

Professional career (1)：

博士(医学) (大阪大学)

Work history (6)：

2022/02 - 現在 Nagasaki University Institute of Tropical Medicine Associate Professor
2023/08 - 2024/05 University of California at Davis Visiting Associate Professor
2020/09 - 2022/01 Nagasaki University Institute of Tropical Medicine Assistant Professor
2016/04 - 2020/08 University of California at Davis Assistant Project Scientist
2013/04 - 2016/03 University of California at Davis Postdoc

Show all

Committee career (1)：

2024/04 - 現在長崎大学大学生物災害等防止安全運営委員会, 委員

Awards (5)：

2023 - 長崎大学インパクト論文賞
2022 - Nagasaki University Award for impact publication
2016 - Japanese Society for Bacteriology Kuroya Award
2012 - Japanese Society for Symposium on Toxins Young Researcher’s Award
2010 - Osaka University Award for Exceptional Academic Excellence in the Doctor Course

Association Membership(s) (3)：

日本免疫学会 , American Society for Microbiology , 日本細菌学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page