Matsuda Jun

Affiliation and department：

Research field (2)： Cell biology , Nephrology

Research keywords (3)： Autophagy , Rho GTPase , Podocyte

Research theme for competitive and other funds (3)：

2024 - 2027 ポドサイトのGIT2に着目したネフローゼ症候群の病態解明
2021 - 2024 糸球体上皮細胞におけるRho-GTPase制御機構を解明する
2017 - 2018 慢性腎臓病に伴うサルコペニアの発症・進行におけるオートファジーの関与について

Papers (31)：

Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Shihomi Maeda, et al. Age-related TFEB downregulation in proximal tubules causes systemic metabolic disorders and occasional apolipoprotein A4-related amyloidosis. JCI insight. 2024
Sho Matsui, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba-Hamano, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Jun Nakamura, et al. Empagliflozin protects the kidney by reducing toxic ALB (albumin) exposure and preventing autophagic stagnation in proximal tubules. Autophagy. 2024
Shihomi Maeda, Shinsuke Sakai, Yoshitsugu Takabatake, Takeshi Yamamoto, Satoshi Minami, Jun Nakamura, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Hiroaki Yonishi, et al. MondoA and AKI and AKI-to-CKD Transition. Journal of the American Society of Nephrology : JASN. 2024
Satoshi Minami, Shinsuke Sakai, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Hiroaki Yonishi, Jun Nakamura, Shihomi Maeda, et al. FGF21 and autophagy coordinately counteract kidney disease progression during aging and obesity. Autophagy. 2023
Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Satoshi Minami, Atsushi Takahashi, Jun Matsuda, Shinsuke Sakai, Hiroaki Yonishi, Shihomi Maeda, et al. TFEB-mediated lysosomal exocytosis alleviates high fat diet-induced lipotoxicity in the kidney. JCI insight. 2023. 8. 4

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MISC (85)：

松田潤. 慢性腎臓病の治療を目指したポドサイトにおけるRac1制御機構の解明. 日本応用酵素協会誌. 2024. 58
松田潤, 島田直幸, 松田佳奈, 高野朋子, 猪阪善隆. Rac1抑制を介したGIT2のポドサイト保護効果. 日本腎臓学会誌(Web). 2024. 66. 4
島田直幸, 松田潤, 松田佳奈, 高野朋子, 猪阪善隆. ポドサイトのGIT2はRac1活性を制御し細胞形態と糸球体濾過バリアを維持する. 日本腎臓学会誌(Web). 2023. 65. 3
前田志穂美, 酒井晋介, 高畠義嗣, 高橋篤史, 難波倫子, 山本毅士, 松田潤, 南聡, 中村隼, 松井翔, et al. MondoAはRubiconを介して尿細管のオートファジー活性を制御し、腎保護的に働く. 日本腎臓学会誌. 2022. 64. 3. 246-246
松田潤, 高野朋子. Rac1制御因子CdGAP(ARHGAP31)はSrc依存的に接着斑を制御しポドサイト機能を維持する. 日本腎臓学会誌(Web). 2021. 63. 4

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Awards (11)：

2024/03 - 第8回ポドサイト研究会優秀演題賞
2020 - the Fonds de recherche du Québec - Santé (FRQS) Postdoctoral Fellowship Award
2019/11 - Research Institute - McGill University Health Centre (RI-MUHC) MeDIC Travel Award
2019/05 - Canadian Society of Nephrology 2019 Annual Meeting Best Abstract Award
2019 - the Uehara Memorial Foundation Research Fellowship

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