Research field (3)：
Bioorganic chemistry
, Synthetic organic chemistry
, Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (8)：
2024 - 2027 Synthesis of P-chiral phosphorus compounds using sulfonamides with high leaving ability
2017 - 2020 Organic superbase/lithium salt-cooperative catalyst system
2014 - 2017 Domino bond-forming reactions by conjugate addition to unsaturated carbonyl compounds and the following redox reactions
2011 - 2013 Tandem bond forming reactions based on oxidative umpolung of organomeallic reagents
2008 - 2011 Asymmetric Addition of carbon, nitrogen, oxygen and sulfur nucleophiles and its application to the synthesis of biologically active compounds
2008 - 2010 Structure of reactive aggregate of lithium reagents and its application to the generation of highly-activated reagents.
2005 - 2008 Development of Efficient Cascade Reactions with Unsaturated Carbonyl
2005 - 2006 3連続不斉点構築法を鍵としたハリクロリンの全合成研究
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Papers (60)：
Yasutomo Yamamoto, Jinka Sho, Kiyoshi Tomioka. Racemic total synthesis of oxomaritidine by iodobenzene-catalyzed oxidative phenolic coupling under mild reaction conditions. Tetrahedron Green Chem. 2024. 3. 100039-100039
Yasutomo Yamamoto, Hiromi Baba, Miki Toriyama, Junpei Matsuoka, Akari Miyawaki, Kiyoshi Tomioka. Synthetic studies on javaberine A: Construction of the tetrahydroprotoberberine framework based on a double hydroamination strategy. Tetrahedron. 2024. 151. 133788-133788
Yasutomo Yamamoto, Kiyoshi Tomioka. Recent Advances in C-C Bond Formation Via Metal-Catalyzed Michael-Type Reactions. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. 2023
Junpei Matsuoka, Maki Terashita, Akari Miyawaki, Kiyoshi Tomioka, Yasutomo Yamamoto. Phosphazene base-catalyzed hydroamination of aminoalkenes for the construction of isoindoline scaffolds: Application to the total synthesis of aristocularine. Tetrahedron Letters. 2022. 89. 153599-153599
