Rchr
J-GLOBAL ID：202001002866315727   Update date: Jul. 26, 2024

Kojima Yusuke

コジマ ユウスケ | Kojima Yusuke
Affiliation and department：
Kyoto University

About Kyoto University


Research field  (3)： Virology ,  Applied biofunctional and bioprocess engineering ,  Tumor biology
Research keywords  (14)： Retrovirus ,  Oligosaccharides ,  Biopharmaceuticals ,  Transgenic chickens ,  Proteases ,  Topoisomerase inhibitors ,  PARP inhibitors ,  Cancer drugs ,  DNA replication stress ,  DNA replication ,  DNA-protein crosslink ,  Cancer ,  DNA repair ,  DNA damage
Research theme for competitive and other funds  (6)：
  • 2024 - 2027 CRISPR-Cas3ゲノム編集に影響を与える因子に関する研究
  • 2023 - 2027 機能強化型肝臓オルガノイドを用いた UTOpiAシステムの開発
  • 2024 - 2025 近傍集積因子解析よるCRISPR-Cas3ゲノム欠失誘導機構の解明
  • 2022 - 2025 近傍集積因子解析よるCRISPR-Cas3ゲノム欠失誘導機構の解明
  • 2021 - 2024 タンパク質障害物を利用したCRISPR-Cas3による遺伝子欠損領域の制御
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Papers (10)：
  • Yuto Kita, Yuya Okuzaki, Youichi Naoe, Joseph Lee, Uikyu Bang, Natsumi Okawa, Akane Ichiki, Tatsuya Jonouchi, Hidetoshi Sakurai, Yusuke Kojima, et al. Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived iPSCs. Stem Cell Reports. 2023
  • Yusuke Kojima, Yuya Okuzaki, Ken-Ichi Nishijima, Shuichiro Moriwaki, Seiya Asai, Hidenori Kaneoka, Shinji Iijima. Regulatory mechanism of chicken lysozyme gene expression in oviducts examined using transgenic technology. Journal of bioscience and bioengineering. 2021. 131. 4. 453-459
  • Jinzhou Huang, Qin Zhou, Ming Gao, Somaira Nowsheen, Fei Zhao, Wootae Kim, Qian Zhu, Yusuke Kojima, Ping Yin, Yong Zhang, et al. Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. Molecular Cell. 2020. 79. 5. 824-835.e5
  • Yusuke Kojima, Yuichi J Machida. DNA-Protein Crosslinks from Environmental Exposure: Mechanisms of Formation and Repair. Environmental and molecular mutagenesis. 2020
  • Yusuke Kojima, Yuka Machida, Sowmiya Palani, Thomas R Caulfield, Evette S Radisky, Scott H Kaufmann, Yuichi J Machida. FAM111A protects replication forks from protein obstacles via its trypsin-like domain. Nature communications. 2020. 11. 1. 1318-1318
ｍore...
MISC (3)：
  • Moriwaki Shuichiro, Kojima Yusuke, Okuzaki Yuya, Asai Seiya, Kaneoka Hidenori, Nishijima Ken-ichi, Iijima Shinji. 3P-239 Oviduct-specific expression of therapeutic protein utilizing chicken lysozyme promoter. 2015. 67. 330-330
  • Kojima Yusuke, Kidani Shunsuke, Kaneoka Hidenori, Nishijima Ken-ichi, Iijima Shinji. 3P-241 Analyses of chicken sialyltransferases. 2015. 67. 331-331
  • Okuzaki Yuya, Kojima Yusuke, Mizutani Akifumi, Nishijima Ken-ichi, Kaneoka Hidenori, Miyake Katsuhide, Iijima Shinji. 1P-043 Analysis of Chicken Sialyltransferase. 2014. 66. 28-28
Books (2)：
  • 実験医学 特集 動き始めたゲノム編集の医療応用
    羊土社 2024 ISBN:9784758125789
  • Cell cycle machinery and its alterations in pancreatic cancer
    Springer New York 2018
Lectures and oral presentations  (14)：
  • Genome Editing in iPS Cells -Applications and Methods-
    (The 9th Annual Meeting for the Japanese Society for Genome Editing 2024)
  • HLA Genome Editing in iPS Cells by RNA-besed CRISPR-Cas3 Method
    (2024)
  • RNAベースCRISPR-Cas3法を用いたiPS細胞におけるゲノム編集
    (第46回日本分子生物学会年会 2023)
  • FAM111A protects replication forks from protein obstacles via its trypsin-like domain
    (Gordon Research Conference 2020)
  • FAM111A protects replication forks from protein obstacles via its trypsin-like domain
    (Gordon Research Seminar 2020)
ｍore...
Education (4)：
  • 2012 - 2015 Nagoya University Graduate School of Engineering Chemistry and Biotechnology
  • 2010 - 2012 Nagoya University Graduate School of Engineering Chemistry and Biotechnology
  • 2006 - 2010 Nagoya University School of Engineering Chemistry and Biotechnology
  • 2003 - 2006 Asahigaoka high school General course
Professional career (3)：
  • 博士(工学) (名古屋大学大学院工学研究科)
  • 修士(工学) (名古屋大学大学院工学研究科)
  • 学士(工学) (名古屋大学工学部)
Work history (4)：
  • 2021/04 - 現在 Center for iPS Cell Research and Application, Kyoto University Department of Clinical application, Hotta Lab Project-specific Research Center Assistant professor
  • 2020/07 - 2021/03 Kyoto University CiRA Department of Clinical Application, Dr. Hotta's Lab Postdoctral Researcher
  • 2020/03 - 2020/06 Mayo Clinic Department of Oncology Research Associate
  • 2015/03 - 2020/03 Mayo Clinic Department of Oncology Research Fellow
Committee career (1)：
  • 2022/06 - 2022/06 Japanese Society for Genome Editing 7th Annual Meeting Committee Member
Awards (4)：
  • 2024/03 - The Japanese Society for Regenerative Medicine Poster Award
  • 2023/11 - CiRA, Kyoto University CiRA 2023 International Symposium Best Poster Presentation Award
  • 2020/03 - Nature Communications Editors' Highlights FAM111A protects replication forks from protein obstacles via its trypsin-like domain
  • 2013/08 - Central Japan Branch of the Society for Biotechnology, Japan Presentation award
Association Membership(s) (3)：
The Molecular Biology Society of Japan ,  The Japanese Society for Regenerative Medicine ,  The Japanese Society for Genome Editing
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