Research field (3)：
Virology
, Applied biofunctional and bioprocess engineering
, Tumor biology
Research keywords (14)：
Retrovirus
, Oligosaccharides
, Biopharmaceuticals
, Transgenic chickens
, Proteases
, Topoisomerase inhibitors
, PARP inhibitors
, Cancer drugs
, DNA replication stress
, DNA replication
, DNA-protein crosslink
, Cancer
, DNA repair
, DNA damage
Research theme for competitive and other funds (2)：
2022 - 2025 近傍集積因子解析よるCRISPR-Cas3ゲノム欠失誘導機構の解明
2021 - 2024 タンパク質障害物を利用したCRISPR-Cas3による遺伝子欠損領域の制御
Papers (10)：
Yuto Kita, Yuya Okuzaki, Youichi Naoe, Joseph Lee, Uikyu Bang, Natsumi Okawa, Akane Ichiki, Tatsuya Jonouchi, Hidetoshi Sakurai, Yusuke Kojima, et al. Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived iPSCs. Stem Cell Reports. 2023
Yusuke Kojima, Yuya Okuzaki, Ken-Ichi Nishijima, Shuichiro Moriwaki, Seiya Asai, Hidenori Kaneoka, Shinji Iijima. Regulatory mechanism of chicken lysozyme gene expression in oviducts examined using transgenic technology. Journal of bioscience and bioengineering. 2021. 131. 4. 453-459
Jinzhou Huang, Qin Zhou, Ming Gao, Somaira Nowsheen, Fei Zhao, Wootae Kim, Qian Zhu, Yusuke Kojima, Ping Yin, Yong Zhang, et al. Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. Molecular Cell. 2020. 79. 5. 824-835.e5
Yusuke Kojima, Yuichi J Machida. DNA-Protein Crosslinks from Environmental Exposure: Mechanisms of Formation and Repair. Environmental and molecular mutagenesis. 2020
Yusuke Kojima, Yuka Machida, Sowmiya Palani, Thomas R Caulfield, Evette S Radisky, Scott H Kaufmann, Yuichi J Machida. FAM111A protects replication forks from protein obstacles via its trypsin-like domain. Nature communications. 2020. 11. 1. 1318-1318
Cell cycle machinery and its alterations in pancreatic cancer
Springer New York 2018
Lectures and oral presentations (11)：
FAM111A protects replication forks from protein obstacles via its trypsin-like domain
(Gordon Research Conference 2020)
FAM111A protects replication forks from protein obstacles via its trypsin-like domain
(Gordon Research Seminar 2020)
Repair of DNA-Protein Crosslinks and Its Implication for Cancer Therapies
(Visiting Faculty Seminar, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic 2020)
2012 - 2015 Nagoya University Graduate School of Engineering Chemistry and Biotechnology
2010 - 2012 Nagoya University Graduate School of Engineering Chemistry and Biotechnology
2006 - 2010 Nagoya University School of Engineering Chemistry and Biotechnology
2003 - 2006 Asahigaoka high school General course
Professional career (3)：
博士(工学) (名古屋大学大学院工学研究科)
修士(工学) (名古屋大学大学院工学研究科)
学士(工学) (名古屋大学工学部)
Work history (4)：
2021/04 - 現在 Center for iPS Cell Research and Application, Kyoto University Department of Clinical application, Hotta Lab Project-specific Research Center Assistant professor
2020/07 - 2021/03 Kyoto University CiRA Department of Clinical Application, Dr. Hotta's Lab Postdoctral Researcher
2020/03 - 2020/06 Mayo Clinic Department of Oncology Research Associate
2015/03 - 2020/03 Mayo Clinic Department of Oncology Research Fellow
Committee career (1)：
2022/06 - 2022/06 Japanese Society for Genome Editing 7th Annual Meeting Committee Member
Awards (4)：
2024/03 - The Japanese Society for Regenerative Medicine Poster Award
2023/11 - CiRA, Kyoto University CiRA 2023 International Symposium Best Poster Presentation Award
2020/03 - Nature Communications Editors' Highlights FAM111A protects replication forks from protein obstacles via its trypsin-like domain
2013/08 - Central Japan Branch of the Society for Biotechnology, Japan Presentation award
Association Membership(s) (3)：
The Molecular Biology Society of Japan
, The Japanese Society for Regenerative Medicine
, The Japanese Society for Genome Editing
