Tominaga Naoomi

トミナガナオオミ | Tominaga Naoomi

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://ds0n.cc.yamaguchi-u.ac.jp/~tominaganaoomi/

Research field (5)： Genomics , Molecular biology , Tumor biology , Tumor diagnostics and therapeutics , Cell biology

Research keywords (6)： Extracellular vesicles , Muscular Dystrophy , Muscle , Aging , Cell-cell communication , Cancer Biology

Research theme for competitive and other funds (5)：

2023 - 2026 出力系時計遺伝子に着目した炎症性腸疾患の病態解明と治療法の展開
2023 - 2026 ゲノム情報と創薬をつなぐ局在評価法の構築
2022 - 2025 Research of linkage of muscle-brain by extracellular vesicles in aging
2021 - 2023 A
2014 - 2016 A

Papers (24)：

Norihiro Yamada, Kana Tominaga, Naoomi Tominaga, Ayumi Kobayashi, Chihiro Niino, Yuta Miyagi, Hirotaka Yamagata, Shin Nakagawa. Glycosylation state of vWF in circulating extracellular vesicles serves as a novel biomarker for predicting depression. MedRxiv. 2024
Riko Fujioka, Takeshi Yamamoto, Akihiro Maruta, Yoshihide Nakamura, Naoomi Tominaga, Masako Inamitsu, Tetsuro Oda, Shigeki Kobayashi, Masafumi Yano. Herpud1 modulates hypertrophic signals independently of calmodulin nuclear translocation in rat myocardium-derived H9C2 cells. Biochemical and biophysical research communications. 2023. 652. 61-67
Chihiro Sakai,Mei Mikawa, Takeshi Yamamoto, Tomoyuki Uchida, Yoshihide Nakamura, Hideaki Akase, Takeshi Suetomi, Naoomi Tominaga, Masako Inamitsu, Tetsuro Oda, Takayuki Okamura, Shigeki Kobayashi, et al. Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice. Biochem Biophys Res Commun. in press. 2022. 623. 51-58
Mei Mikawa, Chihiro Sakai, Takeshi Yamamoto, Yoshihide Nakamura, Shinji Tanaka, Naoomi Tominaga, Masako Inamitsu, Tetsuro Oda, Shigeki Kobayashi, Masafumi Yano. Herpud1 suppress angiotensin II induced hypertrophy in cardiomyocytes. Biochemistry and biophysics reports. 2022. 30. 101248-101248
Naoomi Tominaga. Anti-Cancer Role and Therapeutic Potential of Extracellular Vesicles. Cancers. 2021. 13. 24

ｍore...

MISC (3)：

三河芽生, 山本健, 酒井知尋, 藤岡莉子, 丸田陽裕, 中村吉秀, 稲光正子, 富永直臣, 矢野雅文. 心筋細胞の肥大形成におけるHerpud1遺伝子の役割. 山口医学. 2021. 70. 3. 139-139
富永直臣, 小坂展慶, 落谷孝広. マイクロRNAのがん診断マーカーとしての可能性 (特集早期がん診断の研究最前線). 現代化学. 2013. 504. 37-41
The Roles of Exosome in Cancer Malignancy. 2013. 32. 1. 16-22

Patents (3)：

Books (3)：

Lectures and oral presentations (5)：

Brain metastasis mechanism of breast cancer by cancer-derived exosome through BBB breakdown
(2016)
Cancer-derived exosomes promote brain metastasis by disrupting blood-brain barrier through to change actin dynamics.
(74th Japanese Cancer Association 2015)
Cancer-Derived Extracellular Vesicles Promote Brain Metastasis
(World Preclinical Congress 2015)
Breast cancer-derived extracellular vesicles promote brain metastasis via break down BBB
(The 2015 Congress of the International Society for Extracellular Vesicles (ISEV2015) 2015)
Cancer-derived extracellular vesicles promote brain metastasis by disrupting blood-brain barrier through to change actin dynamics.
(Cold Spring Harbor Laboratory Meeting (Blood Brain Barrier) 2014)

Education (2)：

Professional career (1)：

Work history (8)：

2021/10 - 現在ライフサイクルを通した臓器間ネットワークの統合的理解研究推進体(IINL) 研究代表
2021/03 - 現在 Yamaguchi University Graduate School of Medicine Faculty of Health Sciences Assistant Professor
2017/11 - 2021/01 Massachusetts Institute of Technology Biology Postdoctoral Associate
2017/11 - 2019/10 日本学術振興会海外特別研究員
2017/09 - 2017/10 東京大学医科学研究所分子療法分野特任研究員

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Awards (3)：

2023/03 - 第3回 Yamaguchi Pitch Day in 松下村塾最優秀賞
2015/04 - International Society for Extracellular Vesicles (ISEV) 2015 Scholarship Award Breast cancer-derived extracellular vesicles promote brain metastasis via break down BBB
2013/08 - 5th Japanese Association for RNAi Best Poster Award

Association Membership(s) (5)：

International Society for Extracellular Vesicles , 日本細胞外小胞学会 , 日本癌学会 , 日本筋学会 , 日本分子細胞生物学会

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