Research theme for competitive and other funds (7):
2017 - 2021 Development of Proteinaceous Nanocarrier with the set time delivery address
2016 - 生物が作り出すナノバイオ材料の構造物性に着目した工学・医療への応用展開の模索
2013 - 2016 Proposal of hybrid-type chaperonin reaction mechanism in response to the intracellular environment
2010 - 2012 Elucidation of the intracellular protein folding mechanism?In vivo protein interaction analysis?
2007 - 2011 Reconstitution of prions and protein folding
2008 - 2009 Modeling of an novel reaction cycle and analyses of cellular dynamics of chaperonin GroEL
2006 - 2007 1分子・1細胞レベルでの酵母プリオンのダイナミクス観察
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Papers (32):
Hideki Taguchi, Ayumi Koike-Takeshita. In vivo client proteins of the chaperonin GroEL-GroES provide insight into the role of chaperones in protein evolution. Frontiers in Molecular Biosciences. 2023. 10
Hiromi Yoda, Ayumi Koike-Takeshita. TEM and STEM-EDS evaluation of metal nanoparticle encapsulation in GroEL/GroES complexes according to the reaction mechanism of chaperonin. Microscopy. 2020. 70. 3. 289-296
Ayumi Koike-Takeshita, Takatoshi Arakawa, Hideki Taguchi, Tatsuro Shimamura. Crystal Structure of a Symmetric Football-Shaped GroEL:GroES2-ATP14 Complex Determined at 3.8 Å Reveals Rearrangement between Two GroEL Rings. Journal of Molecular Biology. 2014. 426. 21. 3634-3641
Koike-Takeshita A, Mitsuoka K, Taguchi H. Asp52 in combination with Asp398 plays a critical role in ATP hydrolysis of chaperonin GroEL. J. Biol. Chem. 2014. 289. 43. 30005-30011
Hideshima S, Wustoni, S, Kuroiwa S, Nakanishi, T, Koike-Takeshita A, Osaka T. Monitoring Amyloid Sup35NM Growth with Label-Free Electrical Detection Using a Field-Effect Transistor Biosensor. ChemElectroChem. 2014. 1. 1. 51-54
極限環境生物学会
, The Electrochemical Society of Japan
, Protein Science Society of Japan
, 日本生物工学会
, The Japanese Biochemical Society
, The Molecular Biology Society of Japan