SHIMOKAWA Mariko

Research theme for competitive and other funds (1)：

2020 - 2021 Genetic lineage tracing in human epidermal organoids reveals the evolutionary adaptedness of epidermal stem cells to environmental factors

Papers (11)：

Yuki Ohta, Masayuki Fujii, Sirirat Takahashi, Ai Takano, Kosaku Nanki, Mami Matano, Hikaru Hanyu, Megumu Saito, Mariko Shimokawa, Shingo Nishikori, et al. Cell-matrix interface regulates dormancy in human colon cancer stem cells. Nature. 2022. 608. 7924. 784-794
Keiko Ishikawa, Shinya Sugimoto, Mayumi Oda, Masayuki Fujii, Sirirat Takahashi, Yuki Ohta, Ai Takano, Kazuhiro Ishimaru, Mami Matano, Kosuke Yoshida, et al. Identification of Quiescent LGR5+ Stem Cells in the Human Colon. Gastroenterology. 2022
Kenta Kawasaki, Kohta Toshimitsu, Mami Matano, Masashi Fujita, Masayuki Fujii, Kazuhiro Togasaki, Toshiki Ebisudani, Mariko Shimokawa, Ai Takano, Sirirat Takahashi, et al. An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping. Cell. 2020. 183. 5. 1420-1435
Kosaku Nanki, Masayuki Fujii, Mariko Shimokawa, Mami Matano, Shingo Nishikori, Shoichi Date, Ai Takano, Kohta Toshimitsu, Yuki Ohta, Sirirat Takahashi, et al. Somatic inflammatory gene mutations in human ulcerative colitis epithelium. Nature. 2020. 577. 7789. 254-259
Kosaku Nanki, Kohta Toshimitsu, Ai Takano, Masayuki Fujii, Mariko Shimokawa, Yuki Ohta, Mami Matano, Takashi Seino, Shingo Nishikori, Keiko Ishikawa, et al. Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis. Cell. 2018. 174. 4. 856-869

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