Nishiguchi Tsuyoshi

ニシグチツヨシ | Nishiguchi Tsuyoshi

Affiliation and department：
Job title： Postdoctoral Scholar
Other affiliations (1)：

Tottori University Department of Neuropsychiatry Assistant Professor

Homepage URL (1)： https://profiles.stanford.edu/tsuyoshi-nishiguchi

Research field (1)： Psychiatry

Research keywords (3)：せん妄 , β-ヒドロキシ酪酸 (BHB) , ストレス

Research theme for competitive and other funds (1)：

2022 - 2024 うつ病の新たな病態診断マーカーとしてのβ-ヒドロキシ酪酸の可能性

Papers (13)：

Tsuyoshi Nishiguchi, Kyosuke Yamanishi, Shivani Patel, Johnny R. Malicoat, Nathan James Phuong, Tomoteru Seki, Takaya Ishii, Bun Aoyama, Akiyoshi Shimura, Nipun Gorantla, et al. Discovery of novel protective agents for infection-related delirium through bispectral electroencephalography. Translational Psychiatry. 2024. 14. 1
Yoshitaka Nishizawa, Takehiko Yamanashi, Tsuyoshi Nishiguchi, Naofumi Kajitani, Akihiko Miura, Ryoichi Matsuo, Akimitsu Tanio, Manabu Yamamoto, Teruhisa Sakamoto, Yoshiyuki Fujiwara, et al. The Genome-wide DNA methylation changes in gastrointestinal surgery patients with and without postoperative delirium: Evidence of immune process in its pathophysiology. Journal of psychiatric research. 2024. 177. 249-255
Yoshitaka Nishizawa, Kaitlyn C Thompson, Takehiko Yamanashi, Nadia E Wahba, Taku Saito, Pedro S Marra, Takaaki Nagao, Tsuyoshi Nishiguchi, Kazuki Shibata, Kyosuke Yamanishi, et al. Epigenetic signals associated with delirium replicated across four independent cohorts. Translational psychiatry. 2024. 14. 1. 275-275
Tsuyoshi Nishiguchi, Kazuki Shibata, Kyosuke Yamanishi, Mia Nicole Dittrich, Noah Yuki Islam, Shivani Patel, Nathan James Phuong, Pedro S Marra, Johnny R Malicoat, Tomoteru Seki, et al. The bispectral electroencephalography (BSEEG) method quantifies post-operative delirium-like states in young and aged male mice after head mount implantation surgery. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences. 2024
Pedro Marra, Tomoteru Seki, Yoshitaka Nishizawa, Gloria Chang, Kyosuke Yamanishi, Tsuyoshi Nishiguchi, Kazuki Shibata, Patricia Braun, Gen Shinozaki. Genome-wide DNA methylation analysis in female veterans with military sexual trauma and comorbid PTSD/MDD. Journal of affective disorders. 2024

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MISC (15)：

Tsuyoshi Nishiguchi, Kyosuke Yamanishi, Nipun Gorantla, Akiyoshi Shimura, Tomoteru Seki, Takaya Ishii, Bun Aoyama, Johnny R. Malicoat, Nathan James Phuong, Nicole Jade Dye, et al. LPS-induced delirium-like behavior and microglial activation in mice correlate with bispectral electroencephalography (BSEEG). 2024
Tsuyoshi Nishiguchi, Kazuki Shibata, Kyosuke Yamanishi, Mia Nicole Dittrich, Noah Yuki Islam, Shivani Patel, Nathan James Phuong, Pedro S. Marra, Johnny R. Malicoat, Tomoteru Seki, et al. The bispectral EEG (BSEEG) method quantifies post-operative delirium-like states in young and aged mice after head mount implantation surgery. 2024
西口毅, 三浦明彦, 梶谷直史, 大立博昭, 太田三恵, 国分一男, 小松弘二, 友納弘樹, 辻谷直哉, 岩田正明. 治療に難渋した慢性経過の治療抵抗性統合失調症患者にルラシドンが有効であった1例. 精神神経学雑誌 (Psychiatria et Neurologia Japonica). 2023. 125. 4. 326-326
辻谷直哉, 梶谷直史, 友納弘樹, 小松弘二, 国分一男, 西口毅, 大立博昭, 山梨豪彦, 林皓章, 三浦明彦, et al. 加齢に伴い無感情症を呈した脳梁完全欠損の1例. 精神神経学雑誌. 2023. 125. 2. 167-167
西口毅, 岩田正明, 梶谷直史, 三浦明彦, 松尾諒一, 村上周明, 朴盛弘, 仲田夢人, 坪田潤, 山梨豪彦, et al. ストレス脆弱性の指標としてのβ-ヒドロキシ酪酸の可能性. 日本精神神経学会総会プログラム・抄録集 (日本精神神経学会総会抄録集). 2021. 117th. S561-S561

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Lectures and oral presentations (17)：

The Bispectral EEG (BSEEG) Method Quantifies Post-Operative Delirium-Like States in Young and Aged Mice After Head Mount Implantation Surgery
(14th Annual American Delirium Society Conference 2024)
Mouse model of LPS-induced delirium-like behavior correlates with BSEEG(bi-spectral electroencephalogram)
(13th Annual American Delirium Society Conference 2023)
治療に難渋した慢性経過の治療抵抗性統合失調症患者にルラシドンが有効であった1例
(第61回中国・四国精神神経学会・第44回中国・四国精神保健学会 2021)
Possibility of beta-hydroxybutyrate as an biomarker of stress vulnerability
(2021)
慢性期統合失調症におけるルラシドンの使用経験
(鳥取大学精神疾患研究会 2021)

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Education (2)：

2017 - 2021 Tottori University Faculty of Medicine
2008 - 2014 Hyogo College of Medicine Faculty of Medicine Department of Medicine

Professional career (1)：

the Degree of Doctor of Philosophy in Medical Science (Tottori University)

Work history (9)：

2024/05 - 現在 Stanford University School of Medicine, Psychiatry & Behavioral Sciences, Gen Shinozaki Laboratory Postdoctral Scholar
2022/05 - 2024/04 Stanford University School of Medicine, Psychiatry & Behavioral Sciences, Gen Shinozaki Laboratory Visiting Scholar
2021/10 - 2022/04 Faculty of Medicine, Tottori University Division of Psychiatry Assistant Professor
2019/07 - 2021/09 Tottori University Hospital Department of Psychiatry Clinical Fellow
2019/04 - 2019/06 Tottori University Hospital Department of Emergency Assistant Professor

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Awards (3)：

2024/05 - The Japanese Society of Neuropsychopharmacology (JSNP) NPPR Article Award 2023
2021/12 - 31st Tottori University Neuropsychiatry Alumni Award Stress increases blood beta-hydroxybutyrate levels and prefrontal cortex NLRP3 activity jointly a rodent model.
2021/08 - BPNP2021 Featured Presentation Award Verification of the relationship between the beta-hydroxybutyrate and depressive and anxious behaviors due to stress in rodent models

Association Membership(s) (4)：

The American Delirium Society , Japanese Society of Biological Psychiatry , 日本総合病院精神医学会 , 日本精神神経学会

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