Ise Wataru

イセワタル | Ise Wataru

Affiliation and department：
Job title： Professor
Other affiliations (3)：

Homepage URL (1)： https://sites.google.com/cider.osaka-u.ac.jp/iselab

Research field (2)： Immunology , Virology

Research keywords (3)：抗体 , プラズマ細胞 , T細胞

Research theme for competitive and other funds (11)：

2023 - 2029 防御性・病原性ヘルパー記憶T細胞レパトアの形成・生存・活性化の機構解明と新規免疫制御法の開発
2020 - 2023 プラズマ細胞の長期生存と免疫調節機能を支える分子基盤の解明
2018 - 2021 Analysis of cellular dynamics of long-lived plasma cells identified by using a novel reporter mouse system
2017 - 2020 Molecular mechanisms underlying selection and maintenance of high affinity plasma cells
2013 - 2016 Molecular mechanisms underlying the development and function of follicular helper T cells

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Papers (37)：

Wataru Ise, Tomohiro Kurosaki. Tissues of origin matter to plasma cell longevity. Nature immunology. 2024. 25. 2. 194-195
Takuya Koike, Kentaro Fujii, Kohei Kometani, Noah S Butler, Kenji Funakoshi, Shinya Yari, Junichi Kikuta, Masaru Ishii, Tomohiro Kurosaki, Wataru Ise. Progressive differentiation toward the long-lived plasma cell compartment in the bone marrow. The Journal of experimental medicine. 2023. 220. 2
Kota Itahashi, Takuma Irie, Junichiro Yuda, Shogo Kumagai, Tokiyoshi Tanegashima, Yi-Tzu Lin, Sho Watanabe, Yasushi Goto, Jun Suzuki, Keiju Aokage, et al. BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors. Science immunology. 2022. 7. 76. eabk0957
Hsiao-Wei Tsao, James Kaminski, Makoto Kurachi, R Anthony Barnitz, Michael A DiIorio, Martin W LaFleur, Wataru Ise, Tomohiro Kurosaki, E John Wherry, W Nicholas Haining, et al. Batf-mediated epigenetic control of effector CD8+ T cell differentiation. Science immunology. 2022. 7. 68. eabi4919
Michelle S J Lee, Takeshi Inoue, Wataru Ise, Julia Matsuo-Dapaah, James B Wing, Burcu Temizoz, Kouji Kobiyama, Tomoya Hayashi, Ashwini Patil, Shimon Sakaguchi, et al. B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice. The Journal of experimental medicine. 2022. 219. 2

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MISC (23)：

小池拓矢、伊勢渉. 長寿命形質細胞の同定と分化機構の解明. 臨床免疫・アレルギー科. 2023. 80. 4. 482-488
小池拓矢, 伊勢渉. B cell immunometabolism in germinal center reaction. 月刊臨床免疫・アレルギー科. 2023. 79. 4. 425-431
伊勢渉. 医学用語解説濾胞性ヘルパーT細胞. 炎症と免疫. 2022. 30. 2. 192-195
伊勢渉. 自己反応性B細胞・プラズマ細胞の分化と生存制御. 皮膚科. 2022. 1. 1. 22-29
Shinya Tanaka, Wataru Ise, Yoshihiro Baba, Tomohiro Kurosaki. Silencing and activating anergic B cells. Immunological reviews. 2021. 307. 1. 43-52

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Books (3)：

Lectures and oral presentations (14)：

持続的な抗体応答を支える長期生存プラズマ細胞の分化機構
(第32回抗ウイルス療法学会学術集会・総会 2024)
Generation of long-lived memory plasma cells for durable antibody response
(2nd UTOPIA Symposium 2024)
持続的な抗体応答を支える長期生存プラズマ細胞の分化・生存機構
(日本薬学会第144年会 2024)
Regulation of plasma cell survival and migration to the survival niches for establishing durable antibody response.
(International Symposium on Microbiology and Immunology 2024)
持続的な抗体応答を支える長期生存プラズマ細胞の分化と生存ニッチへの移動機構
(第8回日本骨免疫学会冬期学術集会 2024)

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Education (3)：

Professional career (1)：

Work history (4)：

2021/10 - 現在大阪大学感染症総合教育研究拠点生体応答学チーム教授
2011/04 - 大阪大学免疫学フロンティア研究センター特任准教授
2004/09 - Howard Hughes Medical Institute、Department of pathology and immunology , Washington University in St. Louis 研究員
2000/04 - 東京大学大学院農学生命科学研究科応用生命化学専攻助手

Awards (2)：

Association Membership(s) (3)：

日本農芸化学会 , 日本食品免疫学会 , 日本免疫学会

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