Ochi Yotaro

オチヨウタロウ | Ochi Yotaro

Affiliation and department：
Job title： Assistant professor

Research field (3)： Hematology and oncology , Tumor biology , Molecular biology

Research keywords (5)： Hematological malignancy , Epigenetics , Genetics , Cohesin , splicing

Research theme for competitive and other funds (8)：

2023 - 2030 Epigenomic heterogeneity in cancer
2024 - 2026 Elucidation of the molecular pathogenesis of leukemia based on large-scale epigenomic profiling
2023 - 2026 Development of a Cancer Therapy Platform Targeting RNA Modifications Based on Multilevel Omics Analysis in Hematopoietic Tumors
2023 - 2026 Research aimed at creating innovations such as drug discovery based on the collection and analysis of whole genome sequence data and clinical information on refractory cancers (leukemia, etc.)
2022 - 2024 Molecular Abnormalities Caused by Mutations in Epigenetic Regulators of Leukemia

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Papers (28)：

Momoko Nakamura, Kazuhisa Chonabayashi, Megumi Narita, Yasuko Matsumura, Misato Nishikawa, Yotaro Ochi, Yasuhito Nannya, Masakatsu Hishizawa, Daichi Inoue, Ruud Delwel, et al. Modelling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs. British journal of haematology. 2024
Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, et al. Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood Journal. 2024
Kazunari Aoki, Mizuki Hyuga, Yusuke Tarumoto, Gohei Nishibuchi, Atsushi Ueda, Yotaro Ochi, Seiichi Sugino, Takashi Mikami, Hirokazu Kobushi, Itaru Kato, et al. Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia. Blood. 2023
Tomomi Nishimura, Nobuyuki Kakiuchi, Kenichi Yoshida, Takaki Sakurai, Tatsuki R Kataoka, Eiji Kondoh, Yoshitsugu Chigusa, Masahiko Kawai, Morio Sawada, Takuya Inoue, et al. Evolutionary histories of breast cancer and related clones. Nature. 2023. 620. 7974. 607-614
Yotaro Ochi. [Clinical significance of clonal evolution in chronic myeloid leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2023. 64. 5. 369-375

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MISC (139)：

中村桃子, 蝶名林和久, 丹羽諒, Woltjen Knut, 越智陽太郎, 南谷泰仁, 小川誠司, 高折晃史, 吉田善紀. DDX41の病的バリアントと体細胞変異の機能的差異. 日本血液学会学術集会. 2023. 85回. 48-48
中川正宏, 稲垣良作, 黒田隆, 南谷泰仁, 趙蘭英, 越智陽太郎, 本村公則, 竹田淳恵, 戚星星, 岡崎幸治, et al. 単一細胞マルチオミクス解析によるクローン造血の病態解明. 日本血液学会学術集会. 2023. 85回. 287-287
昆彩奈, 中川正宏, 片岡圭亮, 森拓人, 垣内伸之, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, et al. 骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明. 日本血液学会学術集会. 2023. 85回. 290-290
須川正啓, 奥田瑠璃花, 越智陽太郎, 南谷泰仁, 中村航, Mateos Raul, 飯田直子, 千葉健一, 岡田愛, 木村啓佑, et al. ロングリードシークエンスを用いたder(1;7)(q10;p10)を伴う骨髄異形成症候群における染色体切断点の検索. 日本血液学会学術集会. 2023. 85回. 399-399
渡邊瑞希, 岡知美, 諫田淳也, 岩崎惇, 竹田淳恵, 岡智子, 野吾和宏, 山崎寛章, 三好隆史, 平田大二, et al. 造血器疾患患者で同定される生殖細胞系列変異の取り扱いにおける課題. 日本血液学会学術集会. 2023. 85回. 446-446

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Education (2)：

2016 - 2020 Kyoto University Graduate School of Medicine PhD (Hematology and Oncology)
2005 - 2011 Kyoto University Faculty of Medicine, Department of Medical Science MD (Medicine)

Professional career (1)：

Work history (8)：

2023/04 - 現在 Kyoto University FOREST Principal Investigator
2022/02 - 現在 Kyoto University Department of Pathology and Tumor Biology, Graduate School of Medicine Assistant Professor
2020/04 - 2022/01 Kyoto University Department of Pathology and Tumor Biology, Graduate School of Medicine Program-Specific Assistant Professor
2017/04 - 2020/03 Japan Society for the Promotion of Science Research Fellow
2016/04 - 2020/03 Kyoto University Department of Hematology and Oncology, Graduate School of Medicine Graduate Student/Clinical Fellow

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Committee career (4)：

2023/09 - 現在 Japanese Cancer Association Councilor
2023/06 - 現在 The Japanese Society of Hematology Genome Testing Guideline, Curator
2022/08 - 現在 National Cancer Center Japan Center for Cancer Genomics and Advanced Therapeutics (C-CAT), curator
2020/09 - 現在 The Japanese Society of Hematology Councilor

Awards (13)：

2022/11 - Japan Medical Association Medical Award of The Japan Medical Association
2022/10 - Japanese Cancer Association (JCA) The Young Investigator Awards of the Japanese Cancer Association
2021/09 - Japanese Society of Hematology (JSH) JSH Outstanding Paper Award for Young Investigators
2021/09 - Kyoto University Kyoto University Young Investigator Award (KMYIA
2020/11 - Japan Leukemia Research Fund (JLRF) JLRF Special Award (Clinical Medicine Special Award)

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Association Membership(s) (3)：

The Japanese Society of Internal Medicine , Japanese Cancer Association , Japanese Society of Hematology

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