Yuka Ohshiro

オオシロユカ | Yuka Ohshiro

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Pharmaceuticals - health and biochemistry

Research theme for competitive and other funds (8)：

2021 - 2024 環境中からのレアメタル回収技術を指向した微生物由来金属輸送体の機能解析
2018 - 2021 Role of Mer transporters in the transport of toxic metals and rare metal in Escherichia coli and usability for environmental purification.
2016 - 2018 Molecular breeding for controlling long-distance transport of toxic and nutritional elements in plants
2015 - 2018 Molecular breeding of Arabidopsis plants with cell-type specific promoters and a bacterial mercury transporter MerC
2015 - 2018 Role of Mer transporters in the transport of toxic metals in Escherichia coli.

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Papers (51)：

Ryosuke Nakamura, Takashi Iwai, Yasukazu Takanezawa, Tatsuya Shirahata, Naruki Konishi, Yuka Ohshiro, Shimpei Uraguchi, Mitsuo Tanabe, Yoshinori Kobayashi, Kenji Sakamoto, et al. Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice. Toxicology. 2024. 506. 153867-153867
Shimpei Uraguchi, Yuka Ohshiro, Kaede Abe, Yuta Tsuchiya, Ryosuke Nakamura, Yasukazu Takanezawa, Masako Kiyono. Root cell-type specific expressions of bacterial mercury transporter MerC and plant SNARE SYP121 fusion protein differentially affect cadmium accumulation patterns of Arabidopsis. SOIL SCIENCE AND PLANT NUTRITION. 2023
Yasukazu Takanezawa, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. Gadolinium-based contrast agents suppress adipocyte differentiation in 3T3-L1 cells. Toxicology letters. 2023. 383. 196-203
Yasukazu Takanezawa, Yui Kashiwano, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. Methylmercury drives lipid droplet formation and adipokine expression during the late stages of adipocyte differentiation in 3T3-L1 cells. Toxicology. 2023. 486. 153446-153446
Masako Kiyono, Yuka Ohshiro, Ryosuke Nakamura, Shimpei Uraguchi, Yasukazu Takanezawa. Molecular Toxicology of Methylmercury and Phytoremediation of Toxic Metals for Human Health. BPB Reports. 2023. 6. 4. 126-132

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MISC (16)：

大橋悠暉, 高根沢康一, 酒井和真, 中村亮介, 大城有香, 浦口晋平, 清野正子. Autophgy response to toxic metal exposure in SH-SY5Y neuroblastoma cells. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
高根沢康一, 柏野結, 中村亮介, 大城有香, 浦口晋平, 清野正子. Effect of autophagy on methylmercury-induced lipid droplet formation and adipokine expression in 3T3-L1 cells. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
佐藤正和, 浦口晋平, 萬代麻衣, 大城有香, 中村亮介, 高根沢康一, 清野正子. 亜ヒ酸とカドミウム毒性に対するシロイヌナズナ根端分裂組織の応答の特異性. 日本土壌肥料学会講演要旨集(Web). 2023. 69
浦口晋平, 山村有加, 菅谷翔, 佐藤正和, 大城有香, 中村亮介, 高根沢康一, 清野正子. 根端分裂組織のカドミウム・亜ヒ酸応答におけるNAC型転写因子ANAC044とANAC085の機能分化の可能性. 日本土壌肥料学会講演要旨集(Web). 2023. 69
土屋佑太, 浦口晋平, 月岡輝璃, 西田翔, 大城有香, 中村亮介, 高根沢康一, 清野正子. 微生物由来の金属輸送体MerC多重発現シロイヌナズナの確立の試み. 日本土壌肥料学会講演要旨集(Web). 2023. 69

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Lectures and oral presentations (130)：

有害金属によるオートファジー応答性の解析
(フォーラム2021:衛生薬学・環境トキシコロジー 2021)
有機水銀リアーゼ (MerB) によるメチル水銀の脱メチル化を介した微量無機水銀によるオートファジー応答の解析
(フォーラム2021:衛生薬学・環境トキシコロジー 2021)
MerCによる金属輸送メカニズムに関する研究
(フォーラム2021:衛生薬学・環境トキシコロジー 2021)
ガドリニウム造影剤の臓器蓄積性の検討
(日本薬学会第141年会 2021)
メチル水銀による小胞体ストレスはp62により緩和される
(日本薬学会第141年会 2021)

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Education (1)：

2007 - 2009 Kitasato University Graduate School, Division of Pharmaceutical Sciences Department of Public Health and Molecular Toxicology

Professional career (2)：

Association Membership(s) (1)：

The Pharmaceutical Society of Japan

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